Treatment trials

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

This page lists the recent as well as the ongoing registered medical trials on treatments for the symptoms of myalgic encephalomyelitis (ME) and post-acute sequelae of SARS-CoV-2 infection (PASC) as well as their results - if available.

Abbreviations[edit | edit source]

The following abbreviations and symbols are used in the tables below:

Trial type (TT)
Abbreviation Meaning
NRCT Non-randomized controlled trial
OLT Open-label trial
RCT Randomized controlled trial
Condition of the trial subjects (CS)
Abbreviation Meaning
ME Myalgic encephalomyelitis
Trial phase (TP)
Abbreviation Meaning
1-4 Trial phase 1-4
n/a Trial phase not applicable
Treatment category (TC)
Abbreviation Meaning
C Complementary and alternative medicine
D Drug (pharmacotherapy)
O Other
P Psychotherapy
R Rehabilitation
S Supplements

Completed trials[edit | edit source]

Study completion TC Treatment Targeted symptoms Link / study ID Study results TT TP CS
2022-01-19 O Biosound many NCT05848401 - OLT n/a LC
2022-01-20 O Physical exercise & oxygen cardiopulmonary NCT04898205 OLT n/a LC
2022-01-21 O Virtual SFCAMINA many NCT04593225 - RCT n/a ME
2022-01-31 D Ruconest neurological NCT04705831 - RCT 4 PC
2022-01-31 D S-1226 respiratory NCT04949386 - RCT 2 PC
2022-02-14 S Formula C™ many NCT04828668 inconclusive[1] RCT n/a LC, PC
2022-02-22 D Fluvoxamine (SSRI) parosmia NCT05216614 - RCT 2 PC
2022-02-28 R Computerized cognitive training cognitive NCT05571852 OLT n/a LC, PC
2022-03-07 D Sodium pyruvate nasal spray many NCT04871815 headache-, coughing/sneezing-, hypoxemia-, dyspnea-[2] OLT 2/3 LC, PC
2022-03-10 R Inspiratory muscle training pulmonary, strength NCT04811859 RCT n/a PC
2022-03-15 S Palmitoylethanolamide & Luteolin cognitive NCT05311852 RCT n/a LC
2022-03-30 R Rehabilitation (online) respiratory, neurological NCT05074771 OLT n/a PC
2022-04-22 C Homeopathy many NCT05104749 RCT 3 LC, PC
2022-05-01 R Physical exercise (online) pain, cardiopulmonary capacity, mood, quality of life NCT04983394 RCT n/a PC
2022-06-08 D Prospekta asthenia NCT05074888 negligible improvements[3] RCT 3 PC
2022-06-29 D AXA1125 muscles, fatigue NCT05152849 fatigue-[4] RCT 2 LC
2022-07-01 R Nordic walking fatigue, quality of life NCT05453188 OLT n/a LC, PC
2022-07-18 D LYT-100 respiratory NCT04652518 - RCT 2 PC
2022-07-30 C Laser acupuncture immunological, dyspnea NCT05271500 RCT n/a PC
2022-07-31 O TDCS fatigue, cognition, depression, quality of life NCT05252481 RCT n/a PC
2022-09-01 O Self-management many NCT05268523 RCT 1/2 LC, PC
2022-10-10 S Curcumin & Boswellia serrata & Vitamin C many NCT05150782 OLT n/a LC, PC
2022-10-13 O Virtual self-management many NCT05107440 OLT n/a LC
2022-10-14 R Cardiorespiratory telerehabilitation many NCT04996212 RCT n/a LC, PC
2022-11-18 S Bioarginina C (supplement) physical exhaustion, systemic inflammation, endothelial function NCT04947488 OLT n/a PC
2022-11-20 R High tone power therapy fitness, fatigue NCT05217771 RCT n/a PC
2022-11-30 R Computerized cognitive training fatigue, cognitive NCT05582603 OLT 2 PC
2022-12-01 R Circuit training fitness NCT05323331 RCT n/a PC
2022-12-04 D Probiotic many NCT05080244 - RCT n/a LC
2022-12-05 O Vagus nerve stimulation many NCT05608629 mood+, fatigue-[5] OLT n/a ME
2022-12-10 R Diagrammatic breathing & resistance training many NCT05543551 OLT n/a PC
2022-12-20 R Whole body vibration training fitness, many NCT05119634 RCT n/a PC
2022-12-20 D Emoxypine & Meldonium fatigue NCT05939622 fatigue-[6] RCT 4 PC
2022-12-30 O Pulsed ectromagnetic field / pulmonary rehabilitation pulmonary NCT05379517 RCT n/a PC
2022-12-30 R Physiotherapy (online) fitness, quality of life NCT04742946 OLT n/a LC
2022-12-31 D Oxaloacetate fatigue NCT05273372 fatigue--[7] RCT n/a ME
2022-12-31 R Multidisciplinary rehabilitation (online) many NCT04961333 RCT n/a LC
2022-12-31 O Stellate ganglion block many NCT05812209 OLT n/a LC
2023-01-04 O Vagus nerve stimulation fatigue NCT05679505 RCT n/a PC
2023-01-06 D Medical marijuana (CBD) safety of CBD NCT04997395 CBD is safe[8] OLT 2 LC
2023-01-12 C Homeopathy cough, dyspnea, fatigue NCT05715554 OLT n/a PC
2023-01-15 D Loratidine many CTRI/ 2022/07/043679 - RCT 4 LC
2023-01-23 D Low dose naltrexone & NAD+ fatigue NCT04604704 - OLT 2 PC
2023-01-31 R Balneotherapy & aquatic exercise many NCT05765591 RCT n/a PC
2023-01-31 S Quercetin many NCT05730660 fatigue-, sleep issues-[9] RCT n/a ME
2023-01-31 S ImmunoVita (supplement) many NCT04301609 no significant improvements[10] RCT n/a ME
2023-01-31 R Inspiratory muscle training many NCT05196529 - OLT n/a PC, ME
2023-02-01 R Robotic assisted hand rehabilitation health, independence, range of motion NCT06137716 OLT n/a PC, ME
2023-02-02 R Diaphragmatic exercises / incentive spirometer pulmonary NCT05787275 RCT n/a PC
2023-02-22 D Vortioxetine (SSRI) cognitive NCT05047952 cognitive=[11] RCT 2 PC
2023-02-28 R Pulmonary rehabilitation pulmonary NCT05496842 OLT n/a PC
2023-03-02 O Portable oxygen concentrator pulmonary NCT05212831 OLT n/a LC
2023-03-23 R Pulmonary rehabilitation pulmonary NCT05402007 RCT n/a LC, PC
2023-03-30 O Vagus nerve stimulation neuropsychological NCT05389592 RCT n/a LC, PC
2023-03-31 O Vagus nerve stimulation pain NCT05205577 OLT n/a LC
2023-03-31 D RSLV-132 fatigue NCT04944121 - RCT 2 PC
2023-04-21 S Omega 3 many NCT05121766 RCT 1 PC
2023-05-18 D Dextroamphetamine fog NCT05597722 - RCT 4 PC
2023-05-23 O Hydrogen water & biofeedback many NCT05397626 OLT 1 ME
2023-05-31 R Cardiopulmonary exercise many NCT05035628 RCT n/a LC
2023-05-31 R Physical exercise many NCT05204511 OLT 1 LC, PC
2023-05-31 R Physical exercise many NCT06016192 OLT n/a PC
2023-06-01 C Cupping therapy immunological NCT05901337 OLT n/a PC
2023-06-01 O Hyperbaric oxygen therapy pulmonary NCT05977166 OLT n/a PC
2023-06-06 O Plasma Exchange Therapy many NCT05445674 RCT 2 PC
2023-06-30 P Mindfulness many NCT05566379 OLT n/a LC, PC
2023-06-30 P Adhera (fatigue digital program) many NCT05483829


OLT n/a LC
2023-07-06 R Osteopathy & Physiotherapy fatigue NCT05012826 RCT n/a LC
2023-07-21 S Lithium fatigue, fog NCT05618587 RCT 2 LC
2023-07-27 D TNX-102 SL pain NCT05472090 - RCT 2 PC
2023-07-30 R Physiotherapy with neuromodulation fatigue, sleep, quality of life NCT05681455 RCT n/a PC
2023-07-31 D Valacyclovir & Celecoxib (IMC-2) fatigue, pain, POTS Virios PR CTA - OLT 2 PC
2023-07-31 R Resistance exercise fitness, fatigue NCT04900961 OLT n/a LC
2023-07-31 O TDCS many NCT05780450 OLT n/a LC, PC
2023-08-01 R Physical exercise (online) fitness, sleep, anxiety, depression NCT05381675 RCT n/a PC
2023-08-02 R Cardiorespiratory rehabilitation (online) fatigue, PEM, fitness NCT05973136 OLT n/a PC
2023-08-10 C Homeopathy many NCT06002230 OLT n/a LC
2023-08-11 D PRS-220 pulmonary fibrosis NCT05473533 - RCT 1 n/a
2023-08-30 R Sensory re-education training disability, tactile sensation, handgrip strength NCT05911113 RCT n/a PC
2023-08-30 R Physical exercise many NCT05961462 RCT n/a LC
2023-08-31 R Rehabilitation fatigue NCT05599906 OLT n/a LC
2023-08-31 D Montelukast respiratory NCT04695704 - RCT 3 LC
2023-09-01 S Magnesium & Vitamin D many NCT05630339 RCT n/a PC
2023-09-12 D Metoprolol (beta blocker) tachycardias, POTS, hypertension NCT05096884 - OLT 1 PC
2023-09-12 D Nirmatrelvir & ​Ritonavir (Paxlovid) many NCT05576662 - RCT 2 PC
2023-09-22 R Inspiratory & expiratory muscle training many NCT05597774 RCT n/a LC
2023-09-30 R Physical exercise physical & mental fitness NCT05848518 RCT n/a LC, PC
2023-09-30 P Active coping pain NCT05894629 RCT n/a PC
2023-09-30 D Sulfureous water cardiopulmonary, inflammation NCT06294756 RCT n/a LC, PC
2023-10-01 O GET & CBT many NCT05534997 OLT n/a PC
2023-10-01 D Meplazumab many NCT05813587 RCT 3 PC
2023-10-04 D Somatropin (growth hormone) hormonal NCT03554265 NRCT 3 PC
2023-10-18 D Zofin many NCT05228899 RCT 2 LC
2023-10-30 D Vericiguat fatigue, PEM NCT05697640 RCT 2 PC
2023-10-31 D Medical marijuana many NCT05467904 RCT n/a LC
2023-11-01 D IV Rintatolimod (Ampligen) many NCT05592418 RCT 2 PC, ME
2023-11-03 D Probiotic: VSL#3® many NCT05874089 RCT n/a LC
2023-11-06 O Triphala & HIIT immune system, oxidative stress NCT06208761 inconclusive[12] RCT 2 LC
2023-11-14 R Physical and respiratory rehabilitation many NCT05629884 OLT n/a LC, PC
2023-11-30 R Telerehabilitation many NCT05817032 OLT n/a LC
2023-11-30 P Cognitive training cognitive, anxiety, depression NCT05629897 OLT n/a LC, PC
2023-11-30 P CBT & mindfulness pain, anxiety, depression, insomnia NCT05815693 OLT n/a LC, PC
2023-11-30 C Acupuncture fog, cognitive NCT06144320 RCT n/a PC
2023-11-30 R Physiotherapy many NCT05040893 OLT n/a LC
2023-12-01 D Pimozide tinitus NCT05507372 OLT n/a PC
2023-12-11 D Probiotic many NCT05975034 RCT n/a LC
2023-12-28 C Tai chi strength NCT05501067 RCT n/a PC
2023-12-30 D Fampridine cognitive NCT05274477 RCT n/a PC
2023-12-30 O Stellate ganglion block & Bupivacaine many NCT05638620 OLT 1 LC, PC
2023-12-30 C Yoga & self-management many NCT05697042 OLT n/a LC
2023-12-30 R Rehabilitation fatigue NCT04836351 OLT n/a PC
2023-12-31 O Electrical stimulation pain, fatigue, strength, endurance NCT05200858 RCT n/a LC, PC
2023-12-31 D Niagen cognitive, depression, anxiety NCT04809974 RCT 4 LC
2023-12-31 R Physical exercise cardiopulmonary NCT05566483 OLT n/a LC
2023-12-31 C Yoga & breathing & meditation many NCT05139979 RCT n/a LC, PC
2023-12-31 D Pre-probiotic fatigue NCT06013072 RCT n/a PC
2023-12-31 D Remdesivir many NCT04978259 OLT 4 LC
2023-12-31 D CI-581a, CI-581b (glutamate modulator) depression NCT05690503 RCT 2 PC
2023-12-31 C TaiChi-DTx (software) cognitive, physical activity NCT05419219 OLT n/a LC
2023-12-31 O Hyperbaric oxygen therapy pulmonary NCT04905888 open RCT 2 LC
2023-12-31 R Respiratory music therapy pulmonary, many NCT05231512 OLT n/a PC
2023-12-31 S Creatine many NCT02374112 RCT n/a ME
2024-01-30 O Omega 3 & Telerehabilitation fatigue, fitness, depression, anxiety NCT06063031 RCT n/a PC
2024-01-31 D Beclomethasone hyposmia NCT05970731 RCT 2 LC, PC
2024-01-31 D Bupivacaine many NCT05664711 OLT 1 ME
2024-01-31 R Online respiratory physiotherapy pulmonary NCT05572346 OLT n/a LC
2024-01-31 R Sub-symptom threshold Aerobic rehabilitation many NCT06172803 RCT n/a LC
2024-02-01 C Chinese herbal medicine fatigue NCT05684952 RCT 2 LC
2024-02-01 O Autologous stem-cell transplantation many NCT05669261 OLT 1 LC, PC
2024-02-01 P Psychology sleep, anxiety, depression NCT05951803 RCT n/a LC
2024-02-01 D Solriamfetol fatigue, cognitive NCT04622293 RCT 4 ME
2024-02-29 R Home-based physical training fitness, fatigue, cognitive NCT05360563 OLT n/a PC
2024-02-29 R Cognitive rehabilitation many NCT05731570 OLT n/a LC
2024-02-29 P Self-management many NCT05658536 RCT n/a PC
2024-02-29 O Vagus nerve stimulation dysautonomia, fatigue, dyspnea, PEM, quality of life NCT05630040 RCT n/a LC
2024-02-29 R Physical exercise / incentive spirometry pulmonary, fitness NCT06191367 RCT n/a PC
2024-03-31 R Heart rate variability & biofeedback many NCT05228665 general symptoms- [13] OLT n/a LC

Ongoing trials[edit | edit source]

Estimated study completion TC Treatment Targeted symptoms Link / study ID TT TP CS
2024-03-27 R Rehabilitation many NCT05855356 RCT n/a PC
2024-03-30 P Psychology & breathing exercises many NCT05705154 RCT 1/2 LC
2024-03-31 P Cognitive behavioral therapy fitness, fatigue, anxiety, depression NCT05196451 RCT n/a PC
2024-03-31 D Nirmatrelvir & Ritonavir many NCT05823896 RCT 2 LC
2024-03-31 R Virtual home-based rehabilitation many NCT05298878 OLT n/a LC
2024-03-31 O Nutrition & chronobiology & physical exercise many NCT05719493 OLT n/a ME
2024-03-31 O Low carb diet many NCT05836402 RCT n/a LC
2024-03-31 O Nutrition & physical rehabilitation many NCT05254301 OLT n/a PC
2024-03-31 O Immunoadsorption many NCT05841498 RCT n/a PC
2024-03-31 D BIO 300 respiratory NCT04482595 RCT 2 PC
2024-04-06 O IVIG (immunotherapy) neurological NCT05350774 RCT 2 PC
2024-04-20 R Inspiratory muscle training health parameters, fatigue NCT06091358 OLT n/a LC
2024-04-30 S Oxaloacetate fatigue NCT05840237 RCT n/a LC
2024-04-30 C Bright light fatigue, insomnia, anxiety, depression NCT05677932 RCT n/a LC
2024-04-30 R Home-based physical exercise strength, fatigue, dyspnoea NCT06073002 OLT n/a LC
2024-05-31 P Psychoeducation cognitive NCT05167266 OLT n/a LC
2024-05-31 O Hydroxy gas many NCT06159296 RCT n/a LC
2024-06-01 D Low dose naltrexone (oral) pain, inflammation, fatigue NCT05430152 RCT 2 PC
2024-06-01 D Sirolimus pulmonary fibrosis NCT04948203 OLT 3 COVID
2024-06-07 R Pulmonary rehabilitation (online) / physical activity fitness NCT05299333 RCT n/a PC
2024-06-15 P Amygdala & insula retraining fatigue NCT05851846 OLT n/a LC
2024-06-28 O TDCS & Chlorella Pyreinodosa biomarkers (B12, metilmalonic acid, homocysteine) NCT06255600 RCT n/a LC
2024-06-28 O TDCS many NCT06074848 OLT 2 PC
2024-06-30 O TDCS fatigue, cognition, depression, sleep, pain NCT05753202 OLT n/a PC
2024-06-30 O Faecal microbiota transplantation sleep, anxiety, fatigue NCT05556733 OLT n/a LC, PC
2024-06-30 S Vitamin K2 & D3 biomarkers NCT05356936 OLT n/a LC, PC
2024-06-30 D Temelimab neuropsychiatric NCT05497089 RCT 2 PC
2024-06-30 O Hyperbaric oxygen therapy many NCT04842448 RCT 2 PC
2024-06-30 D LAU-7b many NCT05999435 RCT 2/3 LC
2024-06-30 R Breathing techniques & yoga pulmonary, fatigue NCT05732571 RCT n/a PC
2024-06-30 O Self-management many NCT06208696 NRCT n/a LC
2024-07-01 D Nirmatrelvir & ​Ritonavir (Paxlovid) many NCT05595369 RCT 2 COVID, LC
2024-07-30 R Qigong physical health NCT05675995 OLT n/a LC, PC
2024-07-30 S Lithium many NCT06108297 OLT 1 LC
2024-07-30 S Resveratrol & Quercetin asthma, breathing NCT05601180 RCT n/a LC
2024-07-31 O External encounter counterpulsation fatigue NCT05668039 RCT n/a LC
2024-07-31 O Vagus nerve stimulation many NCT05445427 OLT n/a PC
2024-07-31 R Incentive spirometry many NCT05813873 RCT n/a LC
2024-08-01 O GWAS (Genome-wide association study) many DecodeME GWAS n/a ME
2024-08-31 O Hyperbaric oxygen therapy many NCT06159309 OLT n/a PC
2024-08-31 C Acupuncture & TCM cognitive NCT06042777 RCT n/a LC
2024-08-31 D Cetirizine / Famotidine many NCT05946551 RCT 3 LC
2024-09-01 D Ivabradin POTS NCT05481177 RCT 4 LC, PC
2024-09-01 R Pulmonary rehabilitation pulmonary NCT05244044 RCT n/a LC
2024-09-01 R Diaphragmatic breathing many NCT06330376 RCT n/a PC
2024-09-25 O Ultrasound fatigue NCT06189066 OLT n/a PC
2024-09-30 P Psychotherapeutic intervention many NCT05453201 OLT n/a LC, PC
2024-09-30 O Electronic case management (software) many NCT05019963 RCT n/a LC
2024-09-30 R Cognitive training cognitive NCT05338749 OLT n/a LC, PC
2024-10-08 R Physical exercise (online) fitness, cardiopulmonary, sleep NCT05205460 RCT n/a PC
2024-10-31 R Inspiratory muscle training fitness, blood pressure, neurovascular ctrl. NCT06091384 RCT n/a PC
2024-10-31 D Nirmatrelvir & ​Ritonavir (Paxlovid) many NCT05668091 RCT 2 LC
2024-10-31 O RegeneCyte many NCT05682560 RCT 2 LC
2024-10-31 R Physical exercise cardiopulmonary NCT06065033 OLT n/a LC, PC
2024-10-31 R Multi-disciplinary recovery program many NCT05167227 RCT n/a LC
2024-10-31 D Valacyclovir & Celecoxib fatigue NCT06316843 RCT 2 LC, PC
2024-11-30 D Efgartigimod POTS NCT05633407 RCT 2 PC
2024-11-30 O Hydrogen water fatigue, physical function, stress NCT06227273 OLT n/a ME
2024-12-01 R NeuroFlex (brain training software) cognitive, fatigue, depression NCT05705193 OLT n/a LC
2024-12-01 R Cognitive rehabilitation cognitive NCT0567604 OLT n/a LC
2024-12-01 O Sauna many NCT05931497 OLT n/a LC
2024-12-15 S ImmuneRecov (proteins & supplements) pulmonary NCT06166030 OLT 3 PC
2024-12-30 R Breathing exercises blood oxygen level NCT06165835 OLT n/a LC, PC
2024-12-31 C Multimodal integrative naturopathic therapy many NCT04927403 OLT n/a PC
2024-12-31 O Mindfulness with Muse S™ Headband stress, anxiety NCT05199233 OLT n/a PC
2024-12-31 S Prednisolone & Vitamin B1, B6 and B12 many NCT05638633 RCT 3 PC
2024-12-31 O Photobiomodulation oral complaints NCT05760092 RCT 2 LC
2024-12-31 R Inspiratory muscle training dyspnea NCT05024474 RCT n/a LC, PC
2024-12-31 R Cognitive trainig & physical activity & mindfulness many NCT05846126 RCT n/a LC, PC
2024-12-31 D Metformin many NCT06147050 RCT 3 PC
2024-12-31 D Atorvastatin neurocognitive NCT04904536 OLT 3 LC
2024-12-31 D Prednisolone cognitive NCT05986422 RCT 2 PC
2024-12-31 S Cacao flavonoid fatigue, handgrip strength, perceived wellbeing NCT06064838 OLT n/a LC
2024-12-31 S Melatonin & Zinc many NCT05454683 RCT n/a ME
2024-12-31 R Cardiopulmonary exercise cardiopulmonary NCT05539950 RCT n/a PC, ME
2024-12-31 S Sodium citrate parosmia NCT06204432 RCT 2 PC
2024-12-31 R Physical exercise many NCT05094622 OLT n/a PC, ME
2024-12-31 S Floradapt Intensive GI (Probiotic) GI inflammation, many NCT06211062 RCT 2 ME
2024-12-31 R Interrupted sitting PEM, cognitive, quality of life NCT05453175 RCT n/a LC
2025-01-15 R Chiropractic fatigue NCT05693064 RCT n/a LC
2025-01-30 O Repeat immunoadsorption many NCT05629988 OLT n/a PC, ME
2025-01-31 O CPAP fog, neuropsychological NCT06052514 OLT n/a PC
2025-01-31 S Nicotinamide riboside & MBRT many NCT05703074 RCT 2 LC
2025-01-31 O TDCS many NCT05791812 OLT n/a ME
2025-02-15 O Umbilical cord mesenchymal stem cell therapy caugh NCT05808400 NRCT n/a LC
2025-02-28 O Immunoadsorption many NCT05710770 RCT 2 PC, ME
2025-02-28 S Nitrate physical fatigue NCT05618574 OLT 3 LC
2025-02-28 D DAOIB cognitive NCT05764538 OLT 2 LC
2025-03-01 O Vagus nerve stimulation many NCT05918965 OLT n/a LC
2025-03-30 P CBT & CRT many NCT05732285 OLT n/a many
2025-03-31 O Mild hyperthermia many NCT06204458 RCT n/a PC
2025-03-31 S Immulina TM (supplement) many NCT05524532 RCT n/a PC, ME
2025-03-31 O Apollo wearable many NCT06097442 OLT n/a LC
2025-04-15 P Vimida (app) fatigue, depression, anxiety, quality of life, ... NCT06251518 RCT n/a PC
2025-04-30 C Electro-acupuncture many NCT05890508 RCT n/a LC
2025-04-30 P Mindfulness mental health NCT05676008 OLT n/a LC
2025-04-30 S N-acetylcysteine many NCT0454216 RCT 2 ME
2025-05-15 D Amantadine cognitive, mood NCT06055244 OLT 1 PC
2025-05-15 D Fluvoxamine many NCT05874037 RCT 2/3 LC
2025-05-18 D Fluvoxamine & Metformin fatigue NCT06128967 RCT 3 LC
2025-05-31 D BC007 many NCT05911009 RCT 2 PC
2025-05-31 D Efgartigimod POTS NCT05918978 OLT 2 PC
2025-06-01 S Pycnogenol many NCT05890534 RCT 3 PC
2025-06-01 R Physical exercise many NCT05877534 RCT n/a PC
2025-06-30 R Physical exercise cardiovascular NCT06168006 RCT n/a PC
2025-07-19 C Acupuncture fatigue NCT05212688 RCT 2 LC
2025-07-30 O Diet & fasting many NCT06214455 OLT n/a LC
2025-07-31 D AER002 many NCT05877508 RCT 2 LC
2025-07-31 R Physical exercise (sensors + app) fitness, quality of life NCT05922865 OLT n/a LC
2025-08-31 O Vagus nerve stimulation fatigue NCT06170645 RCT n/a ME
2025-08-31 O Hyperbaric oxygen therapy neurocognitive NCT06118138 OLT n/a PC
2025-08-31 D Anakinra respiratory NCT05926505 RCT 2/3 LC, PC
2025-08-31 O Stellate ganglion block parosmia NCT06255600 RCT 2 PC
2025-09-01 D VIX001 cognitive, neurological NCT05947617 OLT 1 LC, PC
2025-09-01 R Physical exercise fatigue, fitness NCT06142240 OLT n/a LC
2025-09-30 P Balance acceptance and commitment many NCT06231238 RCT 2 LC, PC
2025-09-30 R Supervised computerized active program cognitive, emotional, functional NCT06315894 OLT n/a LC, PC
2025-11-01 S Ciwujia granules many NCT06245642 RCT 4 ME
2025-11-01 S Testofen many NCT05795816 RCT 3 LC
2025-12-01 R Physical and cognitive exercising many NCT05218174 RCT n/a LC, PC
2025-12-01 D Amantadine cognitive, fatigue, anxiety, depression NCT06234462 RCT 2 LC
2025-12-01 D Remdesivir many NCT05911906 RCT 4 LC
2025-12-20 O HB-adMSCs (allogeneic) many NCT05126563 RCT 2 PC
2025-12-30 O Hyperbaric oxygen therapy many NCT06082518 OLT n/a PC
2025-12-31 O IVIG many NCT06159283 RCT 2 LC, PC
2025-12-31 R Water-based activity fatigue, cognitive NCT06142253 OLT n/a LC
2025-12-31 D Imatinib / Infliximab many NCT05220280 OLT 4 LC
2025-12-31 R Rehabilitation & exercise fatigue NCT06156176 RCT n/a LC, PC
2025-12-31 D Ensitrelvir many NCT06161688 RCT 2 LC
2025-12-31 C Complementary & Integrative medicine online many NCT06004362 RCT n/a PC
2025-12-31 D Ibudilast many NCT05513560 RCT 3 PC
2026-01-31 P Mind body intervention many NCT06045338 OLT n/a LC
2026-02-28 C TCM many NCT06095258 RCT 2 LC
2026-02-28 O Stem cell therapy neurological NCT06156241 OLT 1 LC
2026-03-01 S MCTs & Safflower oil fog NCT05705648 RCT n/a PC
2026-03-30 R Comprehensive rehabilitation fatigue NCT06156202 RCT n/a LC
2026-03-31 D AT1001 (Larazotide) many NCT05747534 RCT 2 LC
2026-03-31 D Lp299v many NCT05227170 RCT n/a LC, PC
2026-04-01 O Hyperbaric oxygen therapy many NCT06267300 RCT 3 PC
2026-04-01 P Lightning Process many NCT05236465 OLT n/a ME
2026-04-28 D Nirmatrelvir & ​Ritonavir (Paxlovid) many NCT05852873 RCT 3 PC
2026-05-15 O Stellate ganglion block parosmia NCT06055270 RCT 3 PC
2026-06-01 R Breath control technique many NCT05851859 OLT n/a LC
2026-06-11 D Rapamycin many NCT06257420 OLT n/a ME
2026-08-01 R Incentive spirometrer respiratory training respiratory NCT06231225 OLT n/a LC
2026-12-01 O Diet & self-management (online) many NCT05057676 OLT n/a many
2026-12-31 D Low dose naltrexone POTS NCT05363514 RCT 4 n/a
2028-01-31 R Smell training and trigeminal nerve stimulation parosmia NCT05855369 RCT 2/3 LC, PC
2028-03-01 D Pregabalin many NCT05967052 RCT 2 ME
2028-09-30 O Weight loss fitness NCT05880108 RCT n/a LC
2028-09-30 O Anti-inflammatory diet fatigue, fitness NCT05977179 RCT n/a LC, PC
2029-03-31 R Cognitive rehabilitation many NCT06086379 RCT n/a LC, PC
2029-12-30 D Baricitinib cognitive NCT05858515 RCT 2 PC