Probiotics are microorganisms that are believed to provide health benefits when consumed.
- 1 Health effects
- 2 Efficacy
- 3 Evidence for Commercial Probiotics
- 4 Evidence for specific strains
- 5 Commercial probiotics without evidence
- 6 Suspected to be effective but lacking studies
- 7 Notable studies
- 8 Learn more
- 9 See also
- 10 References
Health effects[edit | edit source]
- Some bacteria species have been shown to inhibit pathogens in the gut through competition or by producing their own antibiotics.
- Probiotics can reduce histamines levels, or increase them.
Efficacy[edit | edit source]
Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.
Evidence for Commercial Probiotics[edit | edit source]
E. Coli Nissle 1917 (Mutaflor)
E. Coli G1-G10 6 species
Prescript Assist[edit | edit source]
Prescript Assist is a commercial probiotic containing 28 soil based bacteria.
Miyarisan[edit | edit source]
Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3[edit | edit source]
Align[edit | edit source]
Bifidobacterium infantis 35624
Culturelle[edit | edit source]
Lactobacillus Rhamnosus GG
Bifido/Maximus[edit | edit source]
Enterogermina[edit | edit source]
Bacillus clausii
Yakult[edit | edit source]
Lactobacillus casei Shirota
DanActive[edit | edit source]
Lactobacillus casei Danone
Bioflorin[edit | edit source]
Enterococcus faecium SF 68
BioGaia[edit | edit source]
Evidence for specific strains[edit | edit source]
Bifidobacteria[edit | edit source]
Cost per Billion CFU can vary from 1 cent to $1.62. A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).
Bifidobacterium infantis 35624[edit | edit source]
One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in chronic fatigue syndrome patients. Another found that B. infantis boosted serotonin levels in the brain.
Commercial probiotics without evidence[edit | edit source]
These are likely harmful because they are known to kill E. coli that is very low in CFS patients.
Common Yogurts[edit | edit source]
Lactobacillus Acidophilus
Suspected to be effective but lacking studies[edit | edit source]
GeneralBiotics Equilibrium 115 strains - none are lactobacillus or bifidobacteria.
Typical Probiotics sold in Health Food Stores[edit | edit source]
Lactobacillus Acidophilus - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.
Megasporebiotic[edit | edit source]
Not sufficient research published
GcMAF Bravo[edit | edit source]
"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains
Lactobacillus[edit | edit source]
Notable studies[edit | edit source]
- 2018, Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review.(Abstract)
- 2018, A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME).(Abstract)
Learn more[edit | edit source]
- 2016, Probiotics cured my chronic fatigue syndrome (Cort Johnson, January 7)
- 2013, A Person with Chronic Fatigue Syndrome Recovers and….a Gut Series Begins
- CFS Remission - Survey of Probiotics Responses
See also[edit | edit source]
References[edit | edit source]
- Travers, Marie-Agnès; Florent, Isabelle; Kohl, Linda; Grellier, Philippe (September 28, 2011). "Probiotics for the Control of Parasites: An Overview". Journal of Parasitology Research. Retrieved March 2, 2021.
- Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M. M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110
- Roman, P.; Carrillo-Trabalón, F.; Sánchez-Labraca, N.; Cañadas, F.; Estévez, A.F.; Cardona, D. (June 15, 2018). "Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review". Beneficial Microbes. 9 (4): 603–611. doi:10.3920/bm2017.0125. ISSN 1876-2883.
- Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8
microbiome The full collection of microscopic organisms (especially bacteria and fungi) which are present in a particular environment, particularly inside the human body.
myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.