From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Probiotics are microorganisms that are believed to provide health benefits when consumed.

Health effects[edit | edit source]

  • Some bacteria species have been shown to inhibit pathogens in the gut[1] through competition or by producing their own antibiotics.
  • Probiotics can reduce histamines levels, or increase them.[citation needed]

Efficacy[edit | edit source]

Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.[citation needed]

Evidence for Commercial Probiotics[edit | edit source]

Mutaflor[edit | edit source]

E. Coli Nissle 1917 (Mutaflor)[citation needed]

Symbioflor-2[edit | edit source]

E. Coli G1-G10 6 species[citation needed]

Prescript Assist[edit | edit source]

Prescript Assist is a commercial probiotic containing 28 soil based bacteria.[citation needed]

Miyarisan[edit | edit source]

Miyarisan is a Japanese probiotic containing clostridium butyricum,[citation needed] a species that consumes lactic acid and produces butyrate.[citation needed]

Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3[edit | edit source]

Clostridium butyricum, Streptococcus faecalis, Bacillus mesentericus[citation needed]

Align[edit | edit source]

Bifidobacterium infantis 35624[citation needed]

Culturelle[edit | edit source]

Lactobacillus Rhamnosus GG[citation needed]

Bifido/Maximus[edit | edit source]

Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus gasseri[citation needed]

Enterogermina[edit | edit source]

Bacillus clausii[citation needed]

Yakult[edit | edit source]

Lactobacillus casei Shirota

DanActive[edit | edit source]

Lactobacillus casei Danone

Bioflorin[edit | edit source]

Enterococcus faecium SF 68[citation needed]

BioGaia[edit | edit source]

Lactobacillus reuteri[citation needed] produces vitamin B12

Evidence for specific strains[edit | edit source]

Bifidobacteria[edit | edit source]

Cost per Billion CFU can vary from 1 cent to $1.62.[citation needed] A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).[citation needed]

Bifidobacterium infantis 35624[edit | edit source]

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in chronic fatigue syndrome patients.[2] Another found that B. infantis boosted serotonin levels in the brain.[citation needed]

Commercial probiotics without evidence[edit | edit source]

These are likely harmful because they are known to kill E. coli that is very low in CFS patients.

Common Yogurts[edit | edit source]

Lactobacillus Acidophilus[citation needed]

Suspected to be effective but lacking studies[edit | edit source]

GeneralBiotics Equilibrium[citation needed] 115 strains - none are lactobacillus or bifidobacteria.

Typical Probiotics sold in Health Food Stores[edit | edit source]

Lactobacillus Acidophilus[citation needed] - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.

Megasporebiotic[edit | edit source]

Not sufficient research published[citation needed]

GcMAF Bravo[edit | edit source]

"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains[citation needed]

Lactobacillus[edit | edit source]

Notable studies[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Travers, Marie-Agnès; Florent, Isabelle; Kohl, Linda; Grellier, Philippe (September 28, 2011). "Probiotics for the Control of Parasites: An Overview". Journal of Parasitology Research. Retrieved March 2, 2021.
  2. Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M.M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110
  3. Roman, P.; Carrillo-Trabalón, F.; Sánchez-Labraca, N.; Cañadas, F.; Estévez, A.F.; Cardona, D. (June 15, 2018). "Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review". Beneficial Microbes. 9 (4): 603–611. doi:10.3920/bm2017.0125. ISSN 1876-2883.
  4. Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8