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Probiotics are microorganisms that are believed to provide health benefits when consumed.

Health effects[edit | edit source]

  • Some bacteria species have been shown to inhibit pathogens in the gut[1] through competition or by producing their own antibiotics.
  • Probiotics can reduce histamines levels, or increase them.[2]
  • CFS Remission - Survey of Probiotics Responses[3]

Efficacy[edit | edit source]

Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.[4].

Evidence for Commercial Probiotics[edit | edit source]

Mutaflor[edit | edit source]

E. Coli Nissle 1917[5]

Symbioflor-2[edit | edit source]

E. Coli G1-G10 6 species[6]

Prescript Assist[edit | edit source]

Prescript Assist is a commercial probiotic containing 28 soil based bacteria.[7]

Miyarisan[edit | edit source]

Miyarisan is a Japanese probiotic containing clostridium butyricum,[8] a species that consumes lactic acid and produces butyrate.[citation needed]

Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3[edit | edit source]

Clostridium butyricum, Streptococcus faecalis, Bacillus mesentericus[9]

Align[edit | edit source]

Bifidobacterium infantis 35624[10][11]

Culturelle[edit | edit source]

Lactobacillus Rhamnosus GG[12]

Bifido|Maximus[edit | edit source]

Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus gasseri[13]

See also Bifidobacteria

Enterogermina[edit | edit source]

Bacillus clausii [14]

Yakult[edit | edit source]

Lactobacillus casei Shirota

DanActive[edit | edit source]

Lactobacillus casei Danone

Bioflorin[edit | edit source]

Enterococcus faecium SF 68[15]

BioGaia[edit | edit source]

Lactobacillus reuteri[16][17] = Produces B12

Suspected to be effective but lacking studies[edit | edit source]

GeneralBiotics Equilibrium[18] 115 strains - none are lactobacillus or bifidobacteria.

Commercial probiotics without evidence[edit | edit source]

These are likely harmful because they are known to kill E. coli that is very low in CFS patients.

Common Yogurts[edit | edit source]

Lactobacillus Acidophilus[19]

Typical Probiotics sold in Health Food Stores[edit | edit source]

Lactobacillus Acidophilus[19] - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.

Megasporebiotic[edit | edit source]

Not sufficient research published[20]

GcMAF Bravo[edit | edit source]

"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains[21]

Species and Strains[edit | edit source]

Evidence for specific strains[edit | edit source]

Bifidobacteria[edit | edit source]

Cost per Billion CFU can vary from 1 cent to $1.62.[22] A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).[23]

Bifidobacterium infantis 35624[edit | edit source]

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in chronic fatigue syndrome patients.[24] Another found that B. infantis boosted serotonin levels in the brain.[citation needed]

Lactobacillus[edit | edit source]

Notable studies[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Hindawi - List of probiotics tested on different eukaryotic pathogens
  2. CFS Remission - Probiotics and histamines
  3. CFS Remission - Survey of Probiotics Responses
  4. CFS Remission - When to take probiotics? - an actual study
  5. CFS Remission - My favorite probiotic: E. Coli Nissle 1917 (Mutaflor)
  6. CFS Remission - Symbioflor-2: Another E. Coli Probiotic
  7. CFS Remission - Prescript-Assist Broad Spectrum Probiotic Prebiotic Complex
  8. CFS Remission - Miyarisan clostridium butyricum revisited
  9. CFS Remission - A new probiotic: Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3
  10. CFS Remission - Align – Bifidobacterium infantis 35624 – a demonstrated probiotic for IBS
  11. CFS Remission - Bifidobacteriun Infantis – another interesting probiotic
  12. CFS Remission - Lactobacillus Rhamnosis: One of the good ones...
  13. CFS Remission - Bifido|Maximus Histamine-Free and D-Lactate Free Probiotic – Review
  14. CFS Remission - Enterogermina – Four Bacillus clausii strains
  15. CFS Remission - Bioflorin – Enterococcus faecium SF 68
  16. CFS Remission - Lactobacillus Reuteri and recommendations on how to take it
  17. CFS Remission - Lactobacillus Reuteri for B12 production
  18. CFS Remission - GeneralBiotics probiotics
  19. 19.019.1 CFS Remission - Should CFS Patients use Lactobacillus Acidophilus? - Probably not
  20. CFS Remission - Megasporebiotic – Preliminary Review
  21. CFS Remission - GcMAF – Bravo Probiotic – a review
  22. CFS Remission - Bifidobacteria probiotics – best bang for the buck!
  23. CFS Remission - Commercial Bifidobacteria probiotics
  24. Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M. M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110 
  25. Roman P, Carrillo-Trabalón F, Sánchez-Labraca N, Cañadas F, Estévez AF, Cardona D. Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review. Benef Microbes. 2018 Apr 26:1-10. doi: 10.3920/BM2017.0125.
  26. Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8 

Myalgic encephalomyelitis or M.E. has different diagnostic criteria to chronic fatigue syndrome; neurological symptoms are required but fatigue is an optional symptom.<ref name="ICP2011primer">{{Citation

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.