Probiotic

Probiotics are microorganisms that are believed to provide health benefits when consumed.

Health effects

Some bacteria species have been shown to inhibit pathogens in the gut^[1] through competition or by producing their own antibiotics.
Probiotics can reduce histamines levels, or increase them.^{[citation needed]}

Efficacy

Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.^{[citation needed]}

Evidence for Commercial Probiotics

Mutaflor

E. Coli Nissle 1917 (Mutaflor)^{[citation needed]}

Symbioflor-2

E. Coli G1-G10 6 species^{[citation needed]}

Prescript Assist

Prescript Assist is a commercial probiotic containing 28 soil based bacteria.^{[citation needed]}

Miyarisan

Miyarisan is a Japanese probiotic containing clostridium butyricum,^{[citation needed]} a species that consumes lactic acid and produces butyrate.^{[citation needed]}

Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3

Clostridium butyricum, Streptococcus faecalis, Bacillus mesentericus^{[citation needed]}

Align

Bifidobacterium infantis 35624^{[citation needed]}

Culturelle

Lactobacillus Rhamnosus GG^{[citation needed]}

Bifido/Maximus

Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus gasseri^{[citation needed]}

Main article: Bifidobacteria

Enterogermina

Bacillus clausii^{[citation needed]}

Yakult

Lactobacillus casei Shirota

DanActive

Lactobacillus casei Danone

Bioflorin

Enterococcus faecium SF 68^{[citation needed]}

BioGaia

Lactobacillus reuteri^{[citation needed]} produces vitamin B12

Evidence for specific strains

Bifidobacteria

Main article: Bifidobacteria

Cost per Billion CFU can vary from 1 cent to $1.62.^{[citation needed]} A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).^{[citation needed]}

Bifidobacterium infantis 35624

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in chronic fatigue syndrome patients.^[2] Another found that B. infantis boosted serotonin levels in the brain.^{[citation needed]}

Commercial probiotics without evidence

These are likely harmful because they are known to kill E. coli that is very low in CFS patients.

Common Yogurts

Lactobacillus Acidophilus^{[citation needed]}

Suspected to be effective but lacking studies

GeneralBiotics Equilibrium^{[citation needed]} 115 strains - none are lactobacillus or bifidobacteria.

Typical Probiotics sold in Health Food Stores

Lactobacillus Acidophilus^{[citation needed]} - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.

Megasporebiotic

Not sufficient research published^{[citation needed]}

GcMAF Bravo

"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains^{[citation needed]}

Lactobacillus

Main article: Lactobacillus

Notable studies

2018, Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review.^[3] (Abstract)
2018, A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME).^[4] (Abstract)

Learn more

References

↑ Travers, Marie-Agnès; Florent, Isabelle; Kohl, Linda; Grellier, Philippe (September 28, 2011). "Probiotics for the Control of Parasites: An Overview". Journal of Parasitology Research. Retrieved March 2, 2021.
↑ Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M.M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110
↑ Roman, P.; Carrillo-Trabalón, F.; Sánchez-Labraca, N.; Cañadas, F.; Estévez, A.F.; Cardona, D. (June 15, 2018). "Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review". Beneficial Microbes. 9 (4): 603–611. doi:10.3920/bm2017.0125. ISSN 1876-2883.
↑ Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8

[Travers2011-1] Travers, Marie-Agnès; Florent, Isabelle; Kohl, Linda; Grellier, Philippe (September 28, 2011). "Probiotics for the Control of Parasites: An Overview". Journal of Parasitology Research. Retrieved March 2, 2021.

[Groeger2013-2] Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M.M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110

[Roman2018-3] Roman, P.; Carrillo-Trabalón, F.; Sánchez-Labraca, N.; Cañadas, F.; Estévez, A.F.; Cardona, D. (June 15, 2018). "Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review". Beneficial Microbes. 9 (4): 603–611. doi:10.3920/bm2017.0125. ISSN 1876-2883.

[Corbitt,_2018-4] Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8

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