Probiotic

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Probiotics are microorganisms that are believed to provide health benefits when consumed.

Health effects[edit | edit source]

  • Some bacteria species have been shown to inhibit pathogens in the gut[1] through competition or by producing their own antibiotics.
  • Probiotics can reduce histamines levels, or increase them.[2]
  • CFS Remission - Survey of Probiotics Responses[3]

Efficacy[edit | edit source]

Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.[4].

Evidence for Commercial Probiotics[edit | edit source]

Mutaflor[edit | edit source]

E. Coli Nissle 1917[5]

Symbioflor-2[edit | edit source]

E. Coli G1-G10 6 species[6]

Prescript Assist[edit | edit source]

Prescript Assist is a commercial probiotic containing 28 soil based bacteria.[7]

Miyarisan[edit | edit source]

Miyarisan is a Japanese probiotic containing clostridium butyricum,[8] a species that consumes lactic acid and produces butyrate.[citation needed]

Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3[edit | edit source]

Clostridium butyricum, Streptococcus faecalis, Bacillus mesentericus[9]

Align[edit | edit source]

Bifidobacterium infantis 35624[10][11]

Culturelle[edit | edit source]

Lactobacillus Rhamnosus GG[12]

Bifido|Maximus[edit | edit source]

Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus gasseri[13]

See also Bifidobacteria

Enterogermina[edit | edit source]

Bacillus clausii [14]

Yakult[edit | edit source]

Lactobacillus casei Shirota

DanActive[edit | edit source]

Lactobacillus casei Danone

Bioflorin[edit | edit source]

Enterococcus faecium SF 68[15]

BioGaia[edit | edit source]

Lactobacillus reuteri[16][17] = Produces B12

Suspected to be effective but lacking studies[edit | edit source]

GeneralBiotics Equilibrium[18] 115 strains - none are lactobacillus or bifidobacteria.

Commercial probiotics without evidence[edit | edit source]

These are likely harmful because they are known to kill E. coli that is very low in CFS patients.

Common Yogurts[edit | edit source]

Lactobacillus Acidophilus[19]

Typical Probiotics sold in Health Food Stores[edit | edit source]

Lactobacillus Acidophilus[19] - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.

Megasporebiotic[edit | edit source]

Not sufficient research published[20]

GcMAF Bravo[edit | edit source]

"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains[21]

Species and Strains[edit | edit source]

Evidence for specific strains[edit | edit source]

Bifidobacteria[edit | edit source]

Cost per Billion CFU can vary from 1 cent to $1.62.[22] A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).[23]

Bifidobacterium infantis 35624[edit | edit source]

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in chronic fatigue syndrome patients.[24] Another found that B. infantis boosted serotonin levels in the brain.[citation needed]

Lactobacillus[edit | edit source]


Notable studies[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Hindawi - List of probiotics tested on different eukaryotic pathogens
  2. CFS Remission - Probiotics and histamines
  3. CFS Remission - Survey of Probiotics Responses
  4. CFS Remission - When to take probiotics? - an actual study
  5. CFS Remission - My favorite probiotic: E. Coli Nissle 1917 (Mutaflor)
  6. CFS Remission - Symbioflor-2: Another E. Coli Probiotic
  7. CFS Remission - Prescript-Assist Broad Spectrum Probiotic Prebiotic Complex
  8. CFS Remission - Miyarisan clostridium butyricum revisited
  9. CFS Remission - A new probiotic: Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3
  10. CFS Remission - Align – Bifidobacterium infantis 35624 – a demonstrated probiotic for IBS
  11. CFS Remission - Bifidobacteriun Infantis – another interesting probiotic
  12. CFS Remission - Lactobacillus Rhamnosis: One of the good ones...
  13. CFS Remission - Bifido|Maximus Histamine-Free and D-Lactate Free Probiotic – Review
  14. CFS Remission - Enterogermina – Four Bacillus clausii strains
  15. CFS Remission - Bioflorin – Enterococcus faecium SF 68
  16. CFS Remission - Lactobacillus Reuteri and recommendations on how to take it
  17. CFS Remission - Lactobacillus Reuteri for B12 production
  18. CFS Remission - GeneralBiotics probiotics
  19. 19.019.1 CFS Remission - Should CFS Patients use Lactobacillus Acidophilus? - Probably not
  20. CFS Remission - Megasporebiotic – Preliminary Review
  21. CFS Remission - GcMAF – Bravo Probiotic – a review
  22. CFS Remission - Bifidobacteria probiotics – best bang for the buck!
  23. CFS Remission - Commercial Bifidobacteria probiotics
  24. Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M. M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, doi:10.4161/gmic.25487, ISSN 1949-0984, PMID 23842110 
  25. Roman P, Carrillo-Trabalón F, Sánchez-Labraca N, Cañadas F, Estévez AF, Cardona D. Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review. Benef Microbes. 2018 Apr 26:1-10. doi: 10.3920/BM2017.0125.
  26. Corbitt, M; Campagnolo, N; Staines, D; Marshall-Gradisnik, S (2018), "A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)", Probiotics Antimicrob Proteins, doi:10.1007/s12602-018-9397-8 

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.