From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Modafinil is a non-stimulant medication used to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder (SWD).[1] In the United States, it is marketed with the name Provigil.

Evidence[edit | edit source]

Modafinal is a suggested treatment for fatigue (increased energy and alertness) in the Canadian Consensus Criteria, with 100mg suggested in the morning and adding another 100mg at noon.[2]

Notable studies[edit | edit source]

  • 2000, Effect of Modafinil on Fatigue Associated with Neurological Illnesses[3]

References[edit | edit source]