Kenny De Meirleir

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Kenny L. De Meirleir, MD, PhD, is a Belgian Internal Medicine doctor specializing in ME/CFS who currently serves as the Medical Director of Whittemore Peterson Institute, Nevada.[1] He frequently partners with numerous myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) researchers in the EU, UK, US, and Australia to further the understanding of the pathophysiology of ME/CFS. From 2000-2007, he was an editor of the now defunct research journal, Journal of Chronic Fatigue Syndrome. He participated in an earlier clinical trial of Ampligen, an immunomodulator for ME/CFS.

Clinic location[edit | edit source]

Professor De Meirleir runs the Himmunitas clinic in Brussels, Belgium and the Whittemore Peterson Institute in Reno, Nevada, in the United States.

Education[edit | edit source]

(As per bio page at Whittemore Peterson Institute)[2]

  • 1970 – 1977 Medical Education, Vrije Universiteit Brussel, Doctor in Medicine (Belgium), Magna cum Laude
  • 1977 – 1982 Internal medicine Residency, Department of Internal Medicine, university Hospital Vrije Universiteit Brussel, under supervision of Prof. Dr. R. Six. Certification in Internal Medicine
  • 1982 – 1984 Resident in Cardiology, Algemeen Ziekenhuis, Vrije Universiteit Brussel, under supervision of Prof. Dr. P. Block, interrupted by military service
  • 1985 Ph.D. in Physiology

Awards[edit | edit source]

  • Solvay Prize
  • NATO Research Award

Court case[edit | edit source]

In April 2018, Dr. Kenny De Meirleir pleaded guilty to the 2009 importation of the antiviral drug Nexavir to Belgium for use in ME/CFS and Lyme disease patients,[3] he did not receive any sentence or fine. De Meirleir was also prosecuted for carrying out illegal experiments on humans, but was found not guilty.[4]

Writing committees[edit | edit source]

Canadian Consensus Criteria[edit | edit source]

Pediatric case definition[edit | edit source]

International Consensus Criteria[edit | edit source]

Books[edit | edit source]

Notable studies[edit | edit source]

Talks and interviews[edit | edit source]

Wetenschap voor Patiënten - ME/cvs Vereniging[edit | edit source]

Invest in ME Conference Speeches[edit | edit source]

ME/CFS Alert[edit | edit source]

IACFS/ME Conference[edit | edit source]

Other[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

Whittemore Peterson Institute

References[edit | edit source]

  1. NVCBR. "Kenny De Meirleir, MD, PhD". Whittemore Peterson Institute. Retrieved July 11, 2019.
  2. http://nvcbr.org/meet-the-team/?team_member=kennydemeirleir#tab-2fc81613def7f57b934
  3. "Uitstel vonnis tegen chronisch vermoeidheidssyndroom-prof". Het Nieuwsblad (in Nederlands). Retrieved March 2, 2019.
  4. NWS, VRT (April 20, 2018). "Ex-VUB-prof die omstreden medicijn invoerde krijgt geen straf". vrtnws.be (in Nederlands). Retrieved March 2, 2019.
  5. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols", Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02
  6. Jason, Leonard A; Jordan, Karen; Miike, Teruhisa; Bell, David S; Lapp, Charles; Torres-Harding, Susan; Rowe, Kathy; Gurwitt, Alan; De Meirleir, Kenny; Van Hoof, Elke LS (2006), "A Pediatric Case Definition for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 13 (2–3): 1–44, doi:10.1300/J092v13n02_01
  7. Carruthers, Bruce M.; van de Sande, Marjorie I.; De Meirleir, Kenny L.; Klimas, Nancy G.; Broderick, Gordon; Mitchell, Terry; Staines, Donald; Powles, A.C. Peter; Speight, Nigel; Vallings, Rosamund; Bateman, Lucinda; Baumgarten-Austrheim, Barbara; Bell, David; Carlo-Stella, Nicoletta; Chia, John; Darragh, Austin; Jo, Daehyun; Lewis, Donald; Light, Alan; Marshall-Gradisnik, Sonya; Mena, Ismael; Mikovits, Judy; Miwa, Kunihisa; Murovska, Modra; Pall, Martin; Stevens, Staci (August 22, 2011). "Myalgic encephalomyelitis: International Consensus Criteria". Journal of Internal Medicine. 270 (4): 327–338. doi:10.1111/j.1365-2796.2011.02428.x. ISSN 0954-6820. PMC 3427890. PMID 21777306.
  8. De Becker, Pascale; McGregor, Neil; De Meirleir, Kenny (December 2001). "A definition‐based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome". Journal of Internal Medicine. 250 (3): 234–240. doi:10.1046/j.1365-2796.2001.00890.x.
  9. Simon Roelens, C. Vincent Herst, Anne D'Haese, Karen De Smet, Marc Frémont, Kenny De Meirleir & Patrick Englebienne. (2001). G-Actin Cleavage Parallels 2-5A-Dependent RNase L Cleavage in Peripheral Blood Mononuclear Cells—Relevance to a Possible Serum-Based Screening Test for Dysregulations in the 2-5A Pathway. Journal of Chronic Fatigue Syndrome, Vol. 8, Iss. 3-4, pp. 63-82. http://dx.doi.org/10.1300/J092v08n03_07
  10. Patrick Englebienne, C. Vincent Herst, Karen De Smet, Anne D'Haese & Kenny De Meirleir. (2001). Interactions Between Rnase L Ankyrin-Like Domain and ABC Transporters as a Possible Origin for Pain, Ion Transport, CNS and Immune Disorders of Chronic Fatigue Immune Dysfunction Syndrome. Journal of Chronic Fatigue Syndrome, Vol. 8, Iss. 3-4, pp. 83-102. http://dx.doi.org/10.1300/J092v08n03_08
  11. Nijs, Jo; De Meirleir, Kenny L.; Coomans, Danny; De Becker, Pascale; Nicolson, Garth L. (2002), "High prevalence of Mycoplasma infections among European chronic fatigue syndrome patients. Examination of four Mycoplasma species in blood of chronic fatigue syndrome patients", FEMS Immunology and Medical Microbiology, 34 (3): 209-14, doi:10.1111/j.1574-695X.2002.tb00626.x, PMID 12423773
  12. Nijs, Jo; Vaes, Peter; Van Hoof, Elke; De Becker, Pascale; McGregor, Neil; De Meirleir, Kenny L. (2002), "Activity Limitations and Participation Restrictions in Patients with Chronic Fatigue Syndrome—Construction of a Disease Specific Questionnaire", Journal of Chronic Fatigue Syndrome, 10 (2): 3-23, doi:10.1300/J092v10n03_02
  13. P. De Becker, N. McGregor & K. De Meirleir. (2002). Possible Triggers and Mode of Onset of Chronic Fatigue Syndrome. Journal of Chronic Fatigue Syndrome, Vol. 10, Iss. 2, pp. 3-18. http://dx.doi.org/10.1300/J092v10n02_02
  14. Nijs, Jo; De Becker, Pascale; Demanet, Christian; McGregor, Neil; Englebienne, Patrick; Verhas, Michel; De Meirleir, Kenny L. (2003), "Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations", Journal of Chronic Fatigue Syndrome, 11 (1): 117-133, doi:10.1300/J092v11n01_03
  15. Nijs, Jo; De Becker, Pascale; De Meirleir, Kenny L.; Demanet, Christian; Vincken, Walter; Schuermans, Daniel; McGregor, Neil (2003), "Associations between bronchial hyperresponsiveness and immune cell parameters in patients with chronic fatigue syndrome", Chest, 123 (4): 998-1007, PMID 12684286
  16. Garth L. Nicolson, Marwan Y. Nasralla, Kenny De Meirleir, Robert Gan & Joerg Haier. (2003). Evidence for Bacterial (Mycoplasma, Chlamydia) and Viral (HHV-6) Co-Infections in Chronic Fatigue Syndrome Patients. Journal of Chronic Fatigue Syndrome, Vol. 11, Iss. 2, pp. 7-19
  17. Nijs, Jo; Vaes, Peter; McGregor, Neil; Lambrecht, Luc; Van Hoof, Elke; De Meirleir, Kenny L. (2003), "Comparison of Activity Limitations/Participation Restrictions Among Fibromyalgia and Chronic Fatigue Syndrome Patients", Journal of Chronic Fatigue Syndrome, 11 (4): 3-18, doi:10.1300/J092v11n04_02
  18. Elke Van Hoof, Danny Coomans, Pascale De Becker, Romain Meeusen, Raymond Cluydts & Kenny De Meirleir. (2003). Hyperbaric Therapy in Chronic Fatigue Syndrome Journal of Chronic Fatigue Syndrome, Vol. 11, Iss. 3, pp. 37-49. DOI:10.1300/J092v11n03_04
  19. Nijs, Jo; De Meirleir, Kenny L.; Coomans, Danny; De Becker, Pascale; Nicolson, Garth L. (2003), "Deregulation of the 2,5A Synthetase RNase L Antiviral Pathway by Mycoplasma spp. in Subsets of Chronic Fatigue Syndrome" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 37-50, doi:10.1300/J092v11n02_04
  20. Nijs, Jo; Coomans, Danny; Nicolson, Garth L.; De Becker, Pascale; Christian, Demanet; De Meirleir, Kenny L. (2003), "Immunophenotyping Predictive of Mycoplasma Infection in Patients with Chronic Fatigue Syndrome?", Journal of Chronic Fatigue Syndrome, 11 (2): 51-69, doi:10.1300/J092v11n02_05
  21. Van Hoof, Elke; De Meirleir, Kenny; Cluydts, Raymond; Coomans, Danny (2003), "The Symptoms and Psychiatric Status of the Bijlmermeer Plane Crash Disaster: Similarities with Chronic Fatigue Syndrome and Gulf War Syndrome", Journal of Chronic Fatigue Syndrome, 11 (3): 3-21, doi:10.1300/J092v11n03_02
  22. Van Hoof, Elke; De Meirleir, Kenny (2004), "The Influence of Chronic Fatigue Syndrome on the Personality Profile: A Case Report", Journal of Chronic Fatigue Syndrome, 12 (3): 63-71, doi:10.1300/J092v12n03_05
  23. Van Hoof, Elke; Coomans, Danny; Cluydts, Raymond; De Meirleir, Kenny (January 2004). "Association Between Fennell Phase Inventory Scores and Immune and RNase-L Parameters in Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (2): 19–34. doi:10.1300/J092v12n02_03. ISSN 1057-3321.
  24. Van Hoof, Elke; Coomans, Danny; Cluydts, Raymond; De Meirleir, Kenny (2004). "The Fennell Phase Inventory in a Belgian Sample". Journal of Chronic Fatigue Syndrome. 12 (1): 53–69. doi:10.1300/J092v12n01_04.
  25. Van Hoof, E; De Becker, P; De Meirleir, K (2006), "Pediatric Chronic Fatigue Syndrome and Munchausen-By-Proxy: A Case Study", Journal of Chronic Fatigue Syndrome, 13 (2–3): 45-53, doi:10.1300/J092v13n02_02
  26. Frémont, Marc; Vaeyens, Freya; Herst, C. Vincent; De Meirleir, Kenny; Englebienne, Patrick (2006), "Antiviral Pathway Deregulation of Chronic Fatigue Syndrome Induces Nitric Oxide Production in Immune Cells That Precludes a Resolution of the Inflammatory Response", Journal of Chronic Fatigue Syndrome, 13 (4): 17-28, doi:10.1300/J092v13n04_03
  27. Javierre, Casimiro; Alegre, José; Ventura, José Luis; García-Quintana, Ana; Segura, Ramon; Suarez, Andrea; Morales, Alberto; Comella, Agusti; De Meirleir, Kenny L. (2007), "Physiological Responses to Arm and Leg Exercise in Women Patients with Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 14 (1): 43-53, doi:10.1300/J092v14n01_05
  28. Van Hoof, E; De Becker, P; Lapp, C; Cluydts, R; De Meirleir, K (2007), "Defining the Occurrence and Influence of Alpha-Delta Sleep in Chronic Fatigue Syndrome", The American Journal of the Medical Sciences, 333 (2): 78-84, PMID 17301585
  29. Frémont, Marc; Metzger, Kristine; Rady, Hamada; Hulstaert, Jan; De Meirleir, Kenny (2009), "Detection of Herpesviruses and Parvovirus B19 in Gastric and Intestinal Mucosa of Chronic Fatigue Syndrome Patients", In Vivo, 23 (2): 209-213
  30. Sheedy, John R.; Wettenhall, Richard E.H.; Scanlon, Denis; Gooley, Paul R.; Lewis, Donald P.; McGregor, Neil; Stapleton, David; Butt, Henry L.; De Meirleir, Kenny L. (2009), "Increased D-Lactic Acid Intestinal Bacteria in Patients with Chronic Fatigue Syndrome", In Vivo, 23 (4): 621-628, PMID 19567398
  31. Jason, Leonard; Porter, Nicole; Shelleby, E; Till, L; Bell, David S; Lapp, Charles W; Rowe, Kathy; De Meirleir, Kenny (2009), "Severe versus Moderate criteria for the new pediatric case definition for ME/CFS", Child Psychiatry and Human Development, 40 (4): 609-20, doi:10.1007/s10578-009-0147-8
  32. De Meirleir, KL; Khaiboullina, SF; Frémont, M; Hulstaert, J; Rizvanov, AA; Palotás, A; Lombardi, VC (2013), "Plasmacytoid Dendritic Cells in the Duodenum of Individuals Diagnosed with Myalgic Encephalomyelitis Are Uniquely Immunoreactive to Antibodies to Human Endogenous Retroviral Proteins", In Vivo, 27 (2): 177–187, PMID 23422476
  33. Khaiboullina, Svetlana F.; DeMeirleir, Kenny L.; Rawat, Shanti; Berk, Grady S.; Gaynor-Berk, Rory S.; Mijatovic, Tatjana; Blatt, Natalia; Rizvanov, Albert A.; Young, Sheila G.; Lombardi, Vincent C. (March 1, 2015). "Cytokine expression provides clues to the pathophysiology of Gulf War illness and myalgic encephalomyelitis". Cytokine. 72 (1): 1–8. doi:10.1016/j.cyto.2014.11.019. ISSN 1043-4666. PMC 4410698.
  34. Singh, Sahajpreet; Stafford, Phillip; Schlauch, Karen A.; Tillett, Richard R.; Gollery, Martin; Johnston, Stephen Albert; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Mijatovic, Tatjana; Subramanian, Krishnamurthy; Palotás, András; Lombardi, Vincent C. (2016), "Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity", Molecular Neurobiology, doi:10.1007/s12035-016-0334-0
  35. Schlauch, Karen A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Petereit, J; Rizvanov, Albert A; Blatt, Nataliya; Mijatovic, Tatjana; Kulick, D; Palotás, András; Lombardi, Vincent C. (2016), "Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome", Translational Psychiatry, 6 (2): e730, doi:10.1038/tp.2015.208
  36. De Meirleir, Kenny L.; Mijatovic, Tatjana; Subramanian, Krishnamurthy; Schlauch, Karen A.; Lombardi, Vincent C. (2018), "Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis", Journal of Translational Medicine, 16 (1): 322, doi:10.1186/s12967-018-1696-z
  37. http://www.investinme.org/IIMEC2.shtml#agenda
  38. http://www.investinme.org/IIMEC4.shtml#agenda
  39. http://www.investinme.org/IIMEC6.shtml#agenda