Garth Nicolson

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Garth L. Nicolson, PhD, (b.1943), is an American biochemist. He's the Founder, President, and Chief Scientific Officer of The Institute for Molecular Medicine, Huntington Beach, California. His career has covered many scientific and medical areas, but he is best known professionally for advancing the understanding of cell membranes. Nicolson coauthored with S.J. Singer, a classic paper in cell biology,[1] titled "The fluid mosaic model of the structure of cell membranes" in 1972.[2]

Dr. Nicolson has researched the role of chronic infections in a variety of chronic illnesses, including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia, rheumatoid arthritis, Gulf War Illness, and other autoimmune diseases.[3] His extensive work on Gulf War Illness earned him the prestigious awards of an Honorary title of Colonel of the US Army Special Forces and an Honorary title of U.S. Navy SEAL.[4]

Notable studies[edit | edit source]

Book chapters and other publications[edit | edit source]

  • 2018, Mitochondrial Dysfunction and Chronic Disease: Treatment with Membrane Lipid Replacement and Other Natural Supplements[17] - (Full text)

Research Institute location[edit | edit source]

  • Institute Headquarters - Office of the President - 31677 Virginia Way P.O. Box 9355, South Laguna Beach, CA 92652
  • Department of Immunology - 16371 Gothard St., H Huntington Beach, CA, 92647

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ Curriculum Vitae, dated 11/10/15. Retrieved from http://www.immed.org/CV%20files/NOV2015CVupdates/Nicolson,GL-CV2015.5.pdf
  2. ↑ Singer SJ, Nicolson GL. (1972). The fluid mosaic model of the structure of cell membranes. Science,175(4023):720-31. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/4333397
  3. ↑ http://www.immed.org/reachus.htm
  4. ↑ Curriculum Vitae, dated 11/10/15. Retrieved from http://www.immed.org/CV%20files/NOV2015CVupdates/Nicolson,GL-CV2015.5.pdf
  5. ↑ Nicolson, Garth L.; Nasralla, Marwan; Haier, Joerg; Nicolson, Nancy L. (1998). "Diagnosis and Treatment of Chronic Mycoplasmal Infections in Fibromyalgia and Chronic Fatigue Syndromes: Relationship to Gulf War Illness" (PDF). Biomedical Therapy.
  6. ↑ Nijs, Jo; De Meirleir, Kenny L.; Coomans, Danny; De Becker, Pascale; Nicolson, Garth L. (2002), "High prevalence of Mycoplasma infections among European chronic fatigue syndrome patients. Examination of four Mycoplasma species in blood of chronic fatigue syndrome patients", FEMS Immunology and Medical Microbiology, 34 (3): 209-14, doi:10.1111/j.1574-695X.2002.tb00626.x, PMID 12423773
  7. ↑ Agadjanyan, Michael; Vasilevko, Vitaley; Ghochikyan, Anahit; Berns, Paul; Kesslak, Patrick; Nicolson, Robert A. Settineri & Garth L. (2003). "Nutritional Supplement (NT Factor™) Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Aged Subjects". Journal of Chronic Fatigue Syndrome. 11 (3): 23–36.
  8. ↑ Garth L. Nicolson, Marwan Y. Nasralla, Kenny De Meirleir, Robert Gan & Joerg Haier. (2003). Evidence for Bacterial (Mycoplasma, Chlamydia) and Viral (HHV-6) Co-Infections in Chronic Fatigue Syndrome Patients. Journal of Chronic Fatigue Syndrome, Vol. 11, Iss. 2, pp. 7-19. http://dx.doi.org/10.1300/J092v11n02_02
  9. ↑ Nijs J, Nicolson GL, De Becker P, Coomans D, De Meirleir K. (2002). High prevalence of Mycoplasma infections among European chronic fatigue syndrome patients. Examination of four Mycoplasma species in blood of chronic fatigue syndrome patients. Pathogens and Disease, Vol 34, Iss 3, pp 209-214
  10. ↑ Nijs, Jo; De Meirleir, Kenny L.; Coomans, Danny; De Becker, Pascale; Nicolson, Garth L. (2003), "Deregulation of the 2,5A Synthetase RNase L Antiviral Pathway by Mycoplasma spp. in Subsets of Chronic Fatigue Syndrome" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 37-50, doi:10.1300/J092v11n02_04
  11. ↑ Nijs, Jo; Nicolson, Garth L. (2004). "Gulf War Veterans: Evidence for Chromosome Alterations and Their Significance". Journal of Chronic Fatigue Syndrome. 12 (1): 79–83. doi:10.1300/J092v12n01_06.
  12. ↑ Nicolson, Garth L.; Ellithorpe, Rita (2006). "Lipid Replacement and Antioxidant Nutritional Therapy for Restoring Mitochondrial Function and Reducing Fatigue in Chronic Fatigue Syndrome and Other Fatiguing Illnesses". Journal of Chronic Fatigue Syndrome. 13 (1): 57–68.
  13. ↑ Nicolson, Garth L.; Nicolson, Nancy L.; Haier, Joerg (2007), "Chronic Fatigue Syndrome Patients Subsequently Diagnosed with Lyme Disease Borrelia burgdorferi: Evidence for Mycoplasma Species Coinfections", Journal of Chronic Fatigue Syndrome, 14 (4): 5-17, doi:10.3109/10573320802091809
  14. ↑ Nicolson, GL; Ash, ME (2014). "Lipid Replacement Therapy: a natural medicine approach to replacing damaged lipids in cellular membranes and organelles and restoring function". Biochimica et Biophysica Acta. 1838 (6): 1657–79. doi:10.1016/j.bbamem.2013.11.010.
  15. ↑ Nicolson, Garth L. (2014), "Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements", Integrative Medicine: A Clinician's Journal (Encinitas), 13 (4): 35–43, PMC 4566449
  16. ↑ Nicolson, Garth E.; Ash, Michael E. (September 1, 2017). "Membrane Lipid Replacement for chronic illnesses, aging and cancer using oral glycerolphospholipid formulations with fructooligosaccharides to restore phospholipid function in cellular membranes, organelles, cells and tissues". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1859 (9): 1704–1724. doi:10.1016/j.bbamem.2017.04.013. ISSN 0005-2736.
  17. ↑ Nicolson, Garth L.; Ferreira, Gonzalo; Settineri, Robert; Ellithorpe, Rita R.; Breeding, Paul; Ash, Michael E. (2018). "Mitochondrial Dysfunction and Chronic Disease: Treatment with Membrane Lipid Replacement and Other Natural Supplements". In Oliveira, Paulo J. (ed.). Mitochondrial Biology and Experimental Therapeutics. Cham: Springer. pp. 499–522. doi:10.1007/978-3-319-73344-9_22. ISBN 978-3-319-73344-9.
  18. ↑ "IIMEC4". Invest in ME Research. Retrieved February 20, 2020.

cell membrane A very thin membrane, composed of lipids and protein, that surrounds the cytoplasm of a cell and controls the passage of substances into and out of the cell.

chronic illness any long-term illness, regardless of the severity. Chronic illnesses are typically incurable, requiring long-term management.

chronic fatigue (CF) - Persistent and abnormal fatigue is a symptom, not an illness. It may be caused by depression, multiple sclerosis, fibromyalgia, chronic fatigue syndrome or many other illnesses. The term "chronic fatigue" should never be confused with the disease chronic fatigue syndrome.

mitochondria Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.

membrane The word "membrane" can have different meanings in different fields of biology. In cell biology, a membrane is a layer of molecules that surround its contents. Examples of cell-biology membranes include the "cell membrane" that surrounds a cell, the "mitochondrial membranes" that form the outer layers of mitochondria, and the "viral envelope" that surrounds enveloped viruses. In anatomy or tissue biology, a membrane is a barrier formed by a layer of cells. Examples of anatomical membranes include the pleural membranes that surrounds the lungs, the pericardium which surrounds the heart, and some of the layers within the blood-brain barrier.

chronic disease a disease or condition that usually lasts for 3 months or longer and may get worse over time. Chronic diseases are long-term (typically incurable and requiring long-term management) but are not necessarily severe.

membrane The word "membrane" can have different meanings in different fields of biology. In cell biology, a membrane is a layer of molecules that surround its contents. Examples of cell-biology membranes include the "cell membrane" that surrounds a cell, the "mitochondrial membranes" that form the outer layers of mitochondria, and the "viral envelope" that surrounds enveloped viruses. In anatomy or tissue biology, a membrane is a barrier formed by a layer of cells. Examples of anatomical membranes include the pleural membranes that surrounds the lungs, the pericardium which surrounds the heart, and some of the layers within the blood-brain barrier.

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