Neil McGregor

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Neil R. McGregor, BDS, MDSc, PhD, is a senior researcher at the Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia and an Adjunct Professor at Victoria University, Melbourne, Australia.[1] Trained as a periodontist, he developed an interest in ME/CFS research after treating ME/CFS patients with temporomandibular dysfunction syndrome.[2] From 2003-2007, Dr. McGregor was a co-editor of the Journal of Chronic Fatigue Syndrome.[3]

Dr. McGregor is a member of the Working Group which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.[4]

Books[edit | edit source]

Notable studies[edit | edit source]

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Online presence[edit | edit source]

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References[edit | edit source]

  1. ↑ "Neil R Mcgregor". ResearchGate. Retrieved April 24, 2019.
  2. ↑ "Meet the Scientists: Dr Neil McGregor". ME Australia. August 8, 2016. Retrieved April 25, 2019.
  3. ↑ Melbourne, Florienne Loder, University of (January 9, 2017). "Chronic fatigue syndrome a kick in the guts". Pursuit. Retrieved April 25, 2019.
  4. ↑ "OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University". bos.etapestry.com. Retrieved April 25, 2019.
  5. ↑ Meirleir, K. de; McGregor, Neil R.; Van Hoof, Elke L.S. (2006). Pediatric chronic fatigue syndrome. New York: Haworth Medical Press. ISBN 9780789035318. OCLC 70874161.
  6. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in Chronic Fatigue Syndrome". Advances in Clinical Chemistry. 66. Elsevier. pp. 121–172. ISBN 9780128014011.
  7. ↑ McGregor, N.R.; Dunstan, R. H.; Zerbes, M.; Butt, H.L.; Roberts, T.K.; Klineberg, I.J. (June 1996). "Preliminary determination of the association between symptom expression and urinary metabolites in subjects with chronic fatigue syndrome". Biochemical and Molecular Medicine. 58 (1): 85–92. ISSN 1077-3150. PMID 8809350.
  8. ↑ McGregor, N.R.; Dunstan, R. H.; Butt, H.L.; Roberts, T.K.; Klineberg, I.J.; Zerbes, M. (January 1997). "A Preliminary Assessment of the Association of SCL-90-R Psychological Inventory Responses with Changes in Urinary Metabolites in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 3 (1): 17–37. doi:10.1300/J092v03n01_03. ISSN 1057-3321.
  9. ↑ Roberts, Timothy K.; McGregor, Neil R.; Dunstan, R. Hugh; Donohoe, Mark; Murdoch, Raymond N.; Zhang, S.; Hope, D.; Butt, Henry L.; Watkins, Jennifer A.; Taylor, Warren G. (1998). "Immunological and Haematological Parameters in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 4 (4): 51–65. doi:10.1300/J092v04n04_05.
  10. ↑ Richards, R.S.; Roberts, T.K.; Mathers, D.; Dunstan, R.H.; McGregor, N.R.; Butt, H.L. (January 2000). "Investigation of Erythrocyte Oxidative Damage in Rheumatoid Arthritis and Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 6 (1): 37–46. doi:10.1300/J092v06n01_04. ISSN 1057-3321.
  11. ↑ McGregor, Neil R.; Niblett, Suzanne; Bligh, Phillip Clifton; Dunstan, R. Hugh; Fulcher, Greg; Hoskin, Leigh; Butt, Henry L.; Roberts, Timothy K.; King, Katrina (January 2000). "The Biochemistry of Chronic Pain and Fatigue". Journal of Chronic Fatigue Syndrome. 7 (1): 3–21. doi:10.1300/J092v07n01_02. ISSN 1057-3321.
  12. ↑ Richards, R.S.; Roberts, T.K.; McGregor, N.R.; Dunstan, R.H.; Butt, H.L. (February 2000). "Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome". Redox Report. 5 (1): 35–41. doi:10.1179/rer.2000.5.1.35. ISSN 1351-0002.
  13. ↑ Richards, R.S.; Roberts, T.K.; Mathers, D.; Dunstan, R.H.; McGregor, N.R.; Butt, H.L. (January 2000). "Erythrocyte Morphology in Rheumatoid Arthritis and Chronic Fatigue Syndrome: A Preliminary Study". Journal of Chronic Fatigue Syndrome. 6 (1): 23–35. doi:10.1300/J092v06n01_03. ISSN 1057-3321.
  14. ↑ De Becker, P.; McGregor, N.; De Meirleir, K. (September 2001). "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome". Journal of Internal Medicine. 250 (3): 234–240. ISSN 0954-6820. PMID 11555128.
  15. ↑ Nijs, Jo; Vaes, Peter; Van Hoof, Elke; De Becker, Pascale; McGregor, Neil; De Meirleir, Kenny L. (2002), "Activity Limitations and Participation Restrictions in Patients with Chronic Fatigue Syndrome—Construction of a Disease Specific Questionnaire", Journal of Chronic Fatigue Syndrome, 10 (2): 3-23, doi:10.1300/J092v10n03_02
  16. ↑ De Becker, P.; McGregor, N.; De Meirleir, K. (January 2002). "Possible Triggers and Mode of Onset of Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 10 (2): 3–18. doi:10.1300/J092v10n02_02. ISSN 1057-3321.
  17. ↑ Nijs, Jo; De Becker, Pascale; Demanet, Christian; McGregor, Neil; Englebienne, Patrick; Verhas, Michel; De Meirleir, Kenny L. (2003), "Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations", Journal of Chronic Fatigue Syndrome, 11 (1): 117-133, doi:10.1300/J092v11n01_03
  18. ↑ Nijs, Jo; De Becker, Pascale; De Meirleir, Kenny L.; Demanet, Christian; Vincken, Walter; Schuermans, Daniel; McGregor, Neil (2003), "Associations between bronchial hyperresponsiveness and immune cell parameters in patients with chronic fatigue syndrome", Chest, 123 (4): 998-1007, PMID 12684286
  19. ↑ Nijs, Jo; Vaes, Peter; McGregor, Neil; Lambrecht, Luc; Van Hoof, Elke; De Meirleir, Kenny L. (2003), "Comparison of Activity Limitations/Participation Restrictions Among Fibromyalgia and Chronic Fatigue Syndrome Patients", Journal of Chronic Fatigue Syndrome, 11 (4): 3-18, doi:10.1300/J092v11n04_02
  20. ↑ Metcalf, Lee N.; McGregor, Neil R.; Roberts, Timothy K. (January 2004). "Membrane Damaging Toxins from Coagulase-Negative Staphylococcus Are Associated with Self-Reported Temporomandibular Disorder (TMD) in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (3): 25–43. doi:10.1300/J092v12n03_03. ISSN 1057-3321.
  21. ↑ Richards, Ross S.; McGregor, Neil R.; Roberts, Timothy K. (January 2004). "Association Between Oxidative Damage Markers and Self-Reported Temporomandibular Dysfunction Symptoms in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (3): 45–61. doi:10.1300/J092v12n03_04. ISSN 1057-3321.
  22. ↑ Suhadolnik, Robert J.; Peterson, Daniel L.; Reichenbach, Nancy L.; Roen, Gail; Metzger, Melodie; McCahan, John; O'brien, Karen; Welsch, Suzanne; Gabriel, Jerome; Gaughan, John P.; McGregor, Neil R. (2004). "Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction in the RNase L Pathway". Journal of Chronic Fatigue Syndrome. 12 (1): 5–35. doi:10.1300/J092v12n01_02.
  23. ↑ Niblett, Suzanne H.; King, Katrina E.; Dunstan, R. Hugh; Clifton-Bligh, Phillip; Hoskin, Leigh A.; Roberts, Timothy K.; Fulcher, Greg R.; McGregor, Neil R.; Dunsmore, Julie C.; Butt, Henry; Klineberg, Iven; Rothkirch, T.B. (September 2007). "Hematologic and Urinary Excretion Anomalies in Patients with Chronic Fatigue Syndrome". Experimental Biology and Medicine. 232 (8): 1041–1049. doi:10.3181/0702-rm-44. ISSN 1535-3702.
  24. ↑ Sheedy, John R.; Wettenhall, Richard E. H.; Scanlon, Denis; Gooley, Paul R.; Lewis, Donald P.; McGregor, Neil; Stapleton, David I.; Butt, Henry L.; De Meirleir, Kenny L. (July 2009). "Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome". In Vivo (Athens, Greece). 23 (4): 621–628. ISSN 0258-851X. PMID 19567398.
  25. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Sheedy, John R.; Buttfield, Ian; Butt, Henry L.; Gooley, Paul R. (October 2012). "NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome". Clinica Chimica Acta. 413 (19–20): 1525–1531. doi:10.1016/j.cca.2012.06.022.
  26. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in chronic fatigue syndrome". Advances in Clinical Chemistry. 66: 121–172. ISSN 0065-2423. PMID 25344988.
  27. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (December 2015). "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients". Metabolomics. 11 (6): 1626–1639. doi:10.1007/s11306-015-0816-5. ISSN 1573-3882.
  28. ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (July 2, 2016). "Widespread pain and altered renal function in ME/CFS patients". Fatigue: Biomedicine, Health & Behavior. 4 (3): 132–145. doi:10.1080/21641846.2016.1207400. ISSN 2164-1846.
  29. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (January 2017). "The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome". Metabolomics. 13 (1). doi:10.1007/s11306-016-1145-z. ISSN 1573-3882.
  30. ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Gooley, Paul R. (July 4, 2019). "Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases". Diagnostics. 9 (3): 70. doi:10.3390/diagnostics9030070. ISSN 2075-4418.

metabolite A chemical compound produced by, or involved in, metabolism. The term is often used to refer to the degradation products of drugs in the body.

metabolite A chemical compound produced by, or involved in, metabolism. The term is often used to refer to the degradation products of drugs in the body.

membrane The word "membrane" can have different meanings in different fields of biology. In cell biology, a membrane is a layer of molecules that surround its contents. Examples of cell-biology membranes include the "cell membrane" that surrounds a cell, the "mitochondrial membranes" that form the outer layers of mitochondria, and the "viral envelope" that surrounds enveloped viruses. In anatomy or tissue biology, a membrane is a barrier formed by a layer of cells. Examples of anatomical membranes include the pleural membranes that surrounds the lungs, the pericardium which surrounds the heart, and some of the layers within the blood-brain barrier.

The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)[1]

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

involving, related to or in the area of the kidneys[2]

renal involving, related to or in the area of the kidneys

microbiome The full collection of microscopic organisms (especially bacteria and fungi) which are present in a particular environment, particularly inside the human body.

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

metabolomics The analysis of the chemical metabolism within cells, tissues or organisms. The term is often used to refer to the full set of metabolites found in a cell in a given environment.

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