Neil McGregor
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Neil R. McGregor, BDS, MDSc, PhD, is a senior researcher at the Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Australia and an Adjunct Professor at Victoria University, Melbourne, Australia.[1] Trained as a periodontist, he developed an interest in ME/CFS research after treating ME/CFS patients with temporomandibular dysfunction syndrome.[2] From 2003-2007, Dr. McGregor was a co-editor of the Journal of Chronic Fatigue Syndrome.[3]
Dr. McGregor is a member of the Working Group which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.[4]
Books[edit | edit source]
- 2006, Pediatric Chronic Fatigue Syndrome by Kenny de Meirleir, Neil McGregor, and Elke L.S. Van Hoof[5]
- 2014, Chapter Five in Advances in Clinical Chemistry, Vol. 66, published by Elsevier; "Metabolism in Chronic Fatigue Syndrome," by Christopher W. Armstrong, Neil R. McGregor, Henry L. Butt, and Paul R. Gooley[6]
Notable studies[edit | edit source]
- 1996, Preliminary determination of the association between symptom expression and urinary metabolites in subjects with chronic fatigue syndrome[7] - (Abstract)
- 1997, A Preliminary Assessment of the Association of SCL-90-R Psychological Inventory Responses with Changes in Urinary Metabolites in Patients with Chronic Fatigue Syndrome[8] - (Abstract)
- 1998, Immunological and Haematological Parameters in Patients with Chronic Fatigue Syndrome[9] - (Abstract)
- 2000, Investigation of Erythrocyte Oxidative Damage in Rheumatoid Arthritis and Chronic Fatigue Syndrome[10] - (Abstract)
- 2000, The Biochemistry of Chronic Pain and Fatigue[11] - (Abstract)
- 2000, Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome[12] - (Abstract)
- 2000, Erythrocyte Morphology in Rheumatoid Arthritis and Chronic Fatigue Syndrome: A Preliminary Study[13] - (Abstract)
- 2001, A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome[14] - (Full text)
- 2002, Activity Limitations and Participation Restrictions in Patients with Chronic Fatigue Syndrome—Construction of a Disease Specific Questionnaire[15] - (Abstract)
- 2002, Possible Triggers and Mode of Onset of Chronic Fatigue Syndrome[16] - (Abstract)
- 2003, Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations[17] - (Abstract)
- 2003, Associations between bronchial hyperresponsiveness and immune cell parameters in patients with chronic fatigue syndrome[18] - (Abstract)
- 2003, Comparison of Activity Limitations/Participation Restrictions Among Fibromyalgia and Chronic Fatigue Syndrome Patients[19] - (Abstract)
- 2004, Membrane Damaging Toxins from Coagulase-Negative Staphylococcus Are Associated with Self-Reported Temporomandibular Disorder (TMD) in Patients with Chronic Fatigue Syndrome[20] - (Abstract)
- 2004, Association Between Oxidative Damage Markers and Self-Reported Temporomandibular Dysfunction Symptoms in Patients with Chronic Fatigue Syndrome[21] - (Abstract)
- 2004, Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction in the RNase L Pathway[22] - (Full Text)
- 2007, Hematologic and urinary excretion anomalies in patients with chronic fatigue syndrome[23] - (Abstract)
- 2009, Increased d-lactic acid intestinal bacteria in patients with chronic fatigue syndrome[24] - (Full text)
- 2012, NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome[25] - (Abstract)
- 2014, Metabolism in chronic fatigue syndrome[26] - (Abstract)
- 2015, Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients[27] - (Abstract)
- 2016, Widespread pain and altered renal function in ME/CFS patients[28] - (Abstract)
- 2017, The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome[29] - (Abstract)
- 2019, Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases[30] - (Full text)
Talks and interviews[edit | edit source]
- 12 Aug 2017, Community Symposium on the Molecular Basis of ME/CFS - 2017: Speech title - Genome-wide analysis & metabolome changes in ME/CFS
- 14 Mar 2019, An Omic Analysis of ME/CFS – an Assessment of Potential Mechanisms given at the International Research Symposium, Geelong, Australia, sponsored by Emerge Australia
Online presence[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "Neil R Mcgregor". ResearchGate. Retrieved April 24, 2019.
- ↑ "Meet the Scientists: Dr Neil McGregor". ME Australia. August 8, 2016. Retrieved April 25, 2019.
- ↑ Melbourne, Florienne Loder, University of (January 9, 2017). "Chronic fatigue syndrome a kick in the guts". Pursuit. Retrieved April 25, 2019.
- ↑ "OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University". bos.etapestry.com. Retrieved April 25, 2019.
- ↑ Meirleir, K. de; McGregor, Neil R.; Van Hoof, Elke L.S. (2006). Pediatric chronic fatigue syndrome. New York: Haworth Medical Press. ISBN 9780789035318. OCLC 70874161.
- ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in Chronic Fatigue Syndrome". Advances in Clinical Chemistry. 66. Elsevier. pp. 121–172. ISBN 9780128014011.
- ↑ McGregor, N.R.; Dunstan, R. H.; Zerbes, M.; Butt, H.L.; Roberts, T.K.; Klineberg, I.J. (June 1996). "Preliminary determination of the association between symptom expression and urinary metabolites in subjects with chronic fatigue syndrome". Biochemical and Molecular Medicine. 58 (1): 85–92. ISSN 1077-3150. PMID 8809350.
- ↑ McGregor, N.R.; Dunstan, R. H.; Butt, H.L.; Roberts, T.K.; Klineberg, I.J.; Zerbes, M. (January 1997). "A Preliminary Assessment of the Association of SCL-90-R Psychological Inventory Responses with Changes in Urinary Metabolites in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 3 (1): 17–37. doi:10.1300/J092v03n01_03. ISSN 1057-3321.
- ↑ Roberts, Timothy K.; McGregor, Neil R.; Dunstan, R. Hugh; Donohoe, Mark; Murdoch, Raymond N.; Zhang, S.; Hope, D.; Butt, Henry L.; Watkins, Jennifer A.; Taylor, Warren G. (1998). "Immunological and Haematological Parameters in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 4 (4): 51–65. doi:10.1300/J092v04n04_05.
- ↑ Richards, R.S.; Roberts, T.K.; Mathers, D.; Dunstan, R.H.; McGregor, N.R.; Butt, H.L. (January 2000). "Investigation of Erythrocyte Oxidative Damage in Rheumatoid Arthritis and Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 6 (1): 37–46. doi:10.1300/J092v06n01_04. ISSN 1057-3321.
- ↑ McGregor, Neil R.; Niblett, Suzanne; Bligh, Phillip Clifton; Dunstan, R. Hugh; Fulcher, Greg; Hoskin, Leigh; Butt, Henry L.; Roberts, Timothy K.; King, Katrina (January 2000). "The Biochemistry of Chronic Pain and Fatigue". Journal of Chronic Fatigue Syndrome. 7 (1): 3–21. doi:10.1300/J092v07n01_02. ISSN 1057-3321.
- ↑ Richards, R.S.; Roberts, T.K.; McGregor, N.R.; Dunstan, R.H.; Butt, H.L. (February 2000). "Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome". Redox Report. 5 (1): 35–41. doi:10.1179/rer.2000.5.1.35. ISSN 1351-0002.
- ↑ Richards, R.S.; Roberts, T.K.; Mathers, D.; Dunstan, R.H.; McGregor, N.R.; Butt, H.L. (January 2000). "Erythrocyte Morphology in Rheumatoid Arthritis and Chronic Fatigue Syndrome: A Preliminary Study". Journal of Chronic Fatigue Syndrome. 6 (1): 23–35. doi:10.1300/J092v06n01_03. ISSN 1057-3321.
- ↑ De Becker, P.; McGregor, N.; De Meirleir, K. (September 2001). "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome". Journal of Internal Medicine. 250 (3): 234–240. ISSN 0954-6820. PMID 11555128.
- ↑ Nijs, Jo; Vaes, Peter; Van Hoof, Elke; De Becker, Pascale; McGregor, Neil; De Meirleir, Kenny L. (2002), "Activity Limitations and Participation Restrictions in Patients with Chronic Fatigue Syndrome—Construction of a Disease Specific Questionnaire", Journal of Chronic Fatigue Syndrome, 10 (2): 3-23, doi:10.1300/J092v10n03_02
- ↑ De Becker, P.; McGregor, N.; De Meirleir, K. (January 2002). "Possible Triggers and Mode of Onset of Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 10 (2): 3–18. doi:10.1300/J092v10n02_02. ISSN 1057-3321.
- ↑ Nijs, Jo; De Becker, Pascale; Demanet, Christian; McGregor, Neil; Englebienne, Patrick; Verhas, Michel; De Meirleir, Kenny L. (2003), "Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations", Journal of Chronic Fatigue Syndrome, 11 (1): 117-133, doi:10.1300/J092v11n01_03
- ↑ Nijs, Jo; De Becker, Pascale; De Meirleir, Kenny L.; Demanet, Christian; Vincken, Walter; Schuermans, Daniel; McGregor, Neil (2003), "Associations between bronchial hyperresponsiveness and immune cell parameters in patients with chronic fatigue syndrome", Chest, 123 (4): 998-1007, PMID 12684286
- ↑ Nijs, Jo; Vaes, Peter; McGregor, Neil; Lambrecht, Luc; Van Hoof, Elke; De Meirleir, Kenny L. (2003), "Comparison of Activity Limitations/Participation Restrictions Among Fibromyalgia and Chronic Fatigue Syndrome Patients", Journal of Chronic Fatigue Syndrome, 11 (4): 3-18, doi:10.1300/J092v11n04_02
- ↑ Metcalf, Lee N.; McGregor, Neil R.; Roberts, Timothy K. (January 2004). "Membrane Damaging Toxins from Coagulase-Negative Staphylococcus Are Associated with Self-Reported Temporomandibular Disorder (TMD) in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (3): 25–43. doi:10.1300/J092v12n03_03. ISSN 1057-3321.
- ↑ Richards, Ross S.; McGregor, Neil R.; Roberts, Timothy K. (January 2004). "Association Between Oxidative Damage Markers and Self-Reported Temporomandibular Dysfunction Symptoms in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (3): 45–61. doi:10.1300/J092v12n03_04. ISSN 1057-3321.
- ↑ Suhadolnik, Robert J.; Peterson, Daniel L.; Reichenbach, Nancy L.; Roen, Gail; Metzger, Melodie; McCahan, John; O'brien, Karen; Welsch, Suzanne; Gabriel, Jerome; Gaughan, John P.; McGregor, Neil R. (2004). "Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction in the RNase L Pathway". Journal of Chronic Fatigue Syndrome. 12 (1): 5–35. doi:10.1300/J092v12n01_02.
- ↑ Niblett, Suzanne H.; King, Katrina E.; Dunstan, R. Hugh; Clifton-Bligh, Phillip; Hoskin, Leigh A.; Roberts, Timothy K.; Fulcher, Greg R.; McGregor, Neil R.; Dunsmore, Julie C.; Butt, Henry; Klineberg, Iven; Rothkirch, T.B. (September 2007). "Hematologic and Urinary Excretion Anomalies in Patients with Chronic Fatigue Syndrome". Experimental Biology and Medicine. 232 (8): 1041–1049. doi:10.3181/0702-rm-44. ISSN 1535-3702.
- ↑ Sheedy, John R.; Wettenhall, Richard E. H.; Scanlon, Denis; Gooley, Paul R.; Lewis, Donald P.; McGregor, Neil; Stapleton, David I.; Butt, Henry L.; De Meirleir, Kenny L. (July 2009). "Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome". In Vivo (Athens, Greece). 23 (4): 621–628. ISSN 0258-851X. PMID 19567398.
- ↑ Armstrong, Christopher W.; McGregor, Neil R.; Sheedy, John R.; Buttfield, Ian; Butt, Henry L.; Gooley, Paul R. (October 2012). "NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome". Clinica Chimica Acta. 413 (19–20): 1525–1531. doi:10.1016/j.cca.2012.06.022.
- ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in chronic fatigue syndrome". Advances in Clinical Chemistry. 66: 121–172. ISSN 0065-2423. PMID 25344988.
- ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (December 2015). "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients". Metabolomics. 11 (6): 1626–1639. doi:10.1007/s11306-015-0816-5. ISSN 1573-3882.
- ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (July 2, 2016). "Widespread pain and altered renal function in ME/CFS patients". Fatigue: Biomedicine, Health & Behavior. 4 (3): 132–145. doi:10.1080/21641846.2016.1207400. ISSN 2164-1846.
- ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (January 2017). "The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome". Metabolomics. 13 (1). doi:10.1007/s11306-016-1145-z. ISSN 1573-3882.
- ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Gooley, Paul R. (July 4, 2019). "Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases". Diagnostics. 9 (3): 70. doi:10.3390/diagnostics9030070. ISSN 2075-4418.