Fatigue

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Source: Chronic fatigue syndrome: A review (Balachander et al.) 2014.[1]

Fatigue is a feeling of subjective feeling of tiredness, often called by other names including exhaustion. Persistent physical fatigue is a core symptom of chronic fatigue syndrome and a common symptom in many other chronic health conditions.[2][3]

Types of fatigue[edit | edit source]

Desc-i.svg
1.Post-exertional   2.Wired but tired   3.Brain fog
4.Lack of energy for daily life   5. Flu-like fatigue
Source: Jason et al 2009, Disability Studies Quarterly 29(3).[4]

A number of different types of fatigue have been described in people with ME/CFS:

  1. Post-exertional fatigue
  2. Wired fatigue (wired but tired)
  3. Brain fog
  4. Lack of energy for daily living activities
  5. Flu-like fatigue[4]


Prevalence[edit | edit source]

Symptom recognition[edit | edit source]

Persistent fatigue which is not relieved by rest, not life-long, persists over the long term, and does not result from another health condition is a compulsory symptom of chronic fatigue syndrome in the Fukuda criteria.[5]

Multiple types of fatigue are common but optional symptoms of the International Consensus Criteria and Canadian Consensus Criteria for Myalgic Encephalomyelitis.[3]

Fatigue is one of the most common Long COVID symptoms.[6]

Notable studies[edit | edit source]

  • 2016, The aetiopathogenesis of fatigue: unpredictable, complex and persistent[7] (Full Text)
  • 2018, Association of sleep disorders, chronic pain, and fatigue with survival in patients with chronic kidney disease: A meta-analysis of clinical trials[8] (Full Text)

Potential treatments[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 Singh, Shubh Mohan; Sarkar, Siddharth; Rao, Pradyumna; Balachander, Srinivas (July 1, 2014). "Chronic fatigue syndrome: A review". Medical Journal of Dr.D.Y. Patil University. 7 (4): 415. doi:10.4103/0975-2870.135252. ISSN 0975-2870.
  2. ↑ 2.0 2.1 2.2 Jason, Leonard A.; Boulton, Aaron; Porter, Nicole S.; Jessen, Tricia; Njoku, Mary Gloria (2010). "Classification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Types of Fatigue". Behavioral medicine (Washington,D.C.). 36 (1): 24–31. doi:10.1080/08964280903521370. ISSN 0896-4289. PMC 4852700. PMID 20185398.
  3. ↑ 3.0 3.1 Carruthers, B.M.; van de Sande, M.I.; De Meirleir, K.L.; Klimas, N.G.; Broderick, G.; Mitchell, T.; Staines, D.; Powles, A.C.P.; Speight, N. (October 1, 2011). "Myalgic encephalomyelitis: International Consensus Criteria". Journal of Internal Medicine. 270 (4). doi:10.1111/j.1365-2796.2011.02428.x/full. ISSN 1365-2796.
  4. ↑ 4.0 4.1 4.2 Jason, Leonard; Jessen, Tricia; Porter, Nicole; Boulton, Aaron; Njoku, Mary Gloria (July 16, 2009). "Examining Types of Fatigue Among Individuals with ME/CFS". Disability Studies Quarterly. 29 (3). ISSN 2159-8371.
  5. ↑ Fukuda, K.; Straus, S.E.; Hickie, I.; Sharpe, M. C.; Dobbins, J. G.; Komaroff, A. (December 15, 1994). "The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group" (PDF). Annals of Internal Medicine. American College of Physicians. 121 (12): 953–959. ISSN 0003-4819. PMID 7978722.
  6. ↑ Soriano, Joan B.; Allan, Maya; Alsokhn, Carine; Alwan, Nisreen A.; Askie, Lisa; Davis, Hannah E.; Diaz, Janet V.; Dua, Tarun; de Groote, Wouter; Jakob, Robert; Lado, Marta; Marshall, John; Murthy, Srin; Preller, Jacobus; Relan, Pryanka; Schiess, Nicoline; Seahwag, Archana (October 6, 2021), A clinical case definition of post COVID-19 condition by a Delphi consensus, World Health Organization (WHO) clinical case definition working group on post COVID-19 condition, World Health Organization
  7. ↑ Clark, James E.; Fai Ng, W.; Watson, Stuart; Newton, Julia L. (March 2016). "The aetiopathogenesis of fatigue: unpredictable, complex and persistent". British Medical Bulletin. 117 (1): 139–148. doi:10.1093/bmb/ldv057. ISSN 0007-1420. PMC 4782751. PMID 26872857.
  8. ↑ Yang, Xiu Hong; Zhang, Bao Long; Gu, Yan Hong; Zhan, Xiao Li; Guo, Li Li; Jin, Hui Min (November 1, 2018). "Association of sleep disorders, chronic pain, and fatigue with survival in patients with chronic kidney disease: a meta-analysis of clinical trials". Sleep Medicine. 51: 59–65. doi:10.1016/j.sleep.2018.06.020. ISSN 1389-9457.
  9. ↑ Sigurdsson MD, Alex F. (November 8, 2017). "19 Important Causes of Fatigue - Tiredness and Chronic Fatigue Explained". docsopinion.com. Retrieved January 30, 2019.
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