Adrenaline rush

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
(Redirected from Wired but tired)

Adrenaline rush, also called adrenaline crash, and adrenaline surge is a physiological state described by some people with ME/CFS and Long COVID.

Although the word "adrenaline" is used by patients to describe the phenomenon, it is unknown if the release of adrenaline (epinephrine) is the cause of the phenomenon, which is described as being characterised by:[1][2][3]

Prevalence[edit | edit source]

Symptom recognition[edit | edit source]

An adrenaline rush is similar to the state of being "wired but tired", however tiredness is not necessarily a feature of an adrenaline rush.[4] It is not to be confused with a panic attack, as a panic attack has a psychological cause, whilst an adrenaline rush has an organic cause.[5]

Notable studies[edit | edit source]

Possible causes[edit | edit source]

Adrenaline rushes have been described in some patients during and after overexertion, but before post-exertional malaise (or a crash) begins.[1][2]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 Stussman, Barbara; Williams, Ashley; Snow, Joseph; Gavin, Angelique; Scott, Remle; Nath, Avindra; Walitt, Brian (September 18, 2020). "Characterization of Post–exertional Malaise in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Neurology. 11: 1025. doi:10.3389/fneur.2020.01025. ISSN 1664-2295. PMC 7530890. PMID 33071931.
  2. 2.0 2.1 Bested, Alison; Marshall, Lynn (August 18, 2015). "Review of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: an evidence-based approach to diagnosis and management by clinicians". Review of Environmental Health. 30 (4): 223–249.
  3. Dryden, Jim (March 10, 2021). "Podcast: Loss of smell, heart problems common symptoms for long-haulers". Washington University School of Medicine in St. Louis. Retrieved May 2, 2024.
  4. "Chronische Erschöpfung bedeutet nicht, einfach nur müde zu sein". springermedizin.de (in Deutsch). doi:10.1007/s15014-022-4043-z. PMC 9203140. Retrieved May 2, 2024.
  5. "Panic Disorder: When Fear Overwhelms". National Institute of Mental Health. Retrieved May 2, 2024.

‎‎‎‎‎‎‎‎‎‎‎‎‎‎‎‎‎‎‎