AXA1125
AXA1125 or LIVRQNac is a new drug developed by Axcella Therapeutics which is currently in clinical trials for post-exertional fatigue caused by Long COVID.[1][2] AXA1125 has been described as a "novel composition of amino acids" and a "metabolic modulator" and consists of five amino acids (arginine, glutamine, isoleucine, leucine, and valine) and N-acetylcysteine (NAC).[3]
Contents
Theory[edit | edit source]
AXA1125 is a endogenous metabolic modulator, which means it consists of naturally occurring substances that act in a way that modulates energy metabolism.[3] AXA1125 was designed to treat non-alcoholic liver conditions.[3]
Amino acids and precusors[edit | edit source]
AXA1125 consists of a combination of:
- Arginine
- Glutamine
- Isoleucine
- Leucine
- Valine
- N-acetylcysteine (NAC), a precursor to several amino acids[3]
Evidence[edit | edit source]
Clinicians[edit | edit source]
Risks and safety[edit | edit source]
Costs and availability[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
- Oxford test potential treatment for fatigue in long COVID patients - Oxford University
- Poster: Mechanistic Insights Into AXA1125, a Novel Endogenous Metabolic Modulator Composition, Targeting Multiple NASH Drivers - Axcella Health Inc.
References[edit | edit source]
- ↑ "Oxford to test potential treatment for fatigue in long COVID patients". University of Oxford. Retrieved October 31, 2021.
- ↑ "Axcella commences trial of AXA1125 for Long COVID treatment". clinicaltrialsarena.com. Retrieved October 31, 2021.
- ↑ 3.03.13.23.3 Hamill, Michael J.; Nadine Daou; Arianna Nitzel; Lorena Pantano; Margaret Koziel; Manu V. Chakravarthy (March 2021). "Mechanistic Insights Into AXA1125, a Novel Endogenous Metabolic Modulator Composition, Targeting Multiple NASH Drivers" (PDF). Axcella Health Inc.
endogenous Growing or originating from within an organism.
Oxford University a prestigious university located in Oxford, England renowned for its teaching and research in health and medicine
Oxford University a prestigious university located in Oxford, England renowned for its teaching and research in health and medicine
The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.
