Isoleucine
Isoleucine (Ile) or L-isoleucine or L-iso-leucine is one of the nine essential amino acids for humans,[1] and is also available in branched chain amino acid (BCAA) supplements.[2]
Purpose
Isoleucine is essential for forming hemoglobin, regulating blood sugar levels and energy levels, it also helps with wound healing, removal of nitrogenous wastes, stimulates the immune system, and helps with secreting several hormones.[3]
Isoleucine is a saccharomyces cerevisiae (yeast) metabolite and an E. coli (bacteria) metabolite.[1]
Isoleucine is concentrated in muscle tissues in humans, and like other BCAAs it is mostly oxidized in skeletal muscles rather than the liver.[3][2]
Isoleucine, once catalyzed, contributes to ATP production, which is vital when moving from rest to exercise.[2]
Sources
Dietary sources of isoleucine include meats, fish, cheese, eggs, most seeds, and nuts.[1]
Evidence
ME/CFS
Costs and availability
Available over the counter.
Branch-Chain Amino Acids
Isoleucine is branched chain amino acid (BCAA) and found in BCAA supplements, along with leucine and valine.[2]
AXA1125
Isoleucine is one of a number of amino acids in AXA1125, which is undergoing clinical trials for a number of uses.
Risks and safety
See also
Learn more
- Isoleucine - PubChem
References
- ↑ 1.0 1.1 1.2 PubChem. "Isoleucine". pubchem.ncbi.nlm.nih.gov. Retrieved October 31, 2021.
- ↑ 2.0 2.1 2.2 2.3 van der Poll, MCG; Luiking, YC; Dejong, CHC; Soeters, PB (September 2, 2009). "Amino Acids". In Caballero, Benjamin (ed.). Guide to Nutritional Supplements. Oxford, UK: Academic Press. pp. 7–8. ISBN 978-0-12-375661-9.
- ↑ 3.0 3.1 "Isoleucine | NCI Thesaurus". National Cancer Institute. Retrieved November 1, 2021.
