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Immunoadsorption is the technique by which pathogenic substances, especially undesirable antibodies, are removed from blood plasma. Immunoadsorption is considered to have fewer adverse effects than the use of therapeutic plasma exchange.[1] Several medical conditions, such as multiple sclerosis[2] and chronic inflammatory demyelinating polyneuropathy (CIDP)[3] may use immunoadsorption as part of their medical regimen.

Theory[edit | edit source]

A number of studies have found that a subset of ME/CFS patients have abnormal autoantibodies in their blood; immunoadsorption could be used to remove these autoantibodies with the aim of improving symptoms or potentially curing ME/CFS in those patients.[4]

Evidence[edit | edit source]

  • 2018, Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME[4](Full Text)

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Pham, H. P.; Schwartz, J. (2013). "79 - Immunoadsorption". In Shaz, B. H.; Hillyer, C.D. (eds.). Transfusion medicine and hemostasis: clinical and laboratory aspects (2 ed.). Newnes. pp. 525–527. doi:10.1016/B978-0-12-397164-7.00079-3.
  2. Koziolek, Michael J.; Tampe, Desiree; Bähr, Matthias; Dihazi, Hassan; Jung, Klaus; Fitzner, Dirk; Klingel, Reinhard; Müller, Gerhard A.; Kitze, Bernd (April 26, 2012). "Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis". Journal of Neuroinflammation. 9 (1): 80. doi:10.1186/1742-2094-9-80. ISSN 1742-2094. PMC 3418188. PMID 22537481.
  3. Lehmann, Helmar C.; Hughes, Richard A. C.; Hartung, Hans-Peter (January 1, 2013). "23 - Treatment of chronic inflammatory demyelinating polyradiculoneuropathy". In Said, Gérard; Krarup, Christian (eds.). Handbook of Clinical Neurology. Peripheral Nerve Disorders. 3. 115. Elsevier. pp. 415–427. doi:10.1016/b978-0-444-52902-2.00023-0.
  4. 4.04.1 Scheibenbogen, Carmen; Loebel, Madlen; Freitag, Helma; Krueger, Anne; Bauer, Sandra; Antelmann, Michaela; Doehner, Wolfram; Scherbakov, Nadja; Heidecke, Harald (March 15, 2018). "Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME". PLOS ONE. 13 (3): e0193672. doi:10.1371/journal.pone.0193672. ISSN 1932-6203. PMC 5854315. PMID 29543914.

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

autoantibody An antibody that works against the body's own antigens, a hallmark of autoimmune diseases. Autoantibodies are the opposite of an antibodies.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.