Suzanne Vernon
Suzanne D. Vernon, PhD, is the Research Liaison at Bateman Horne Center of Excellence which specializes in treatment and research for ME/CFS and Fibromyalgia[1] and the Chief Scientific Revolutionary of The BioCollective, a collaborative that provides storage and sales of microbiome samples for research and development.[2]
From November 2007 to May 2015, Dr. Vernon was the Scientific Director of Solve ME/CFS Initiative, formerly known as CFIDS Association of America.[3] While there she recognized that access to well-characterized clinical populations was a barrier to engaging more scientists in ME/CFS research. Thus, she started the Research Institute Without Walls (RIWW), "the first nonprofit patient-centered research initiative focused on identifying diagnostic biomarkers and disease-modifying treatment for ME/CFS.[1] The core of RIWW is the SolveCFS BioBank & Patient Registry.[4]
From May 1990 to October 2007, Dr. Vernon worked for the US Centers for Disease Control, first on the team investigating the human papillomavirus as an opportunistic infection in HIV-infected woman, and then in 1997, she became the CFS research group team leader, under William Reeves, MD, the Director of the CDC Chronic Fatigue Research Program.[5][6]
In 2005, Dr Vernon was one of the authors of the CDC case definition of CFS, commonly called the Reeves criteria.[7]
Talks and interviews[edit | edit source]
- 2012, "Cognition & CFS: What Do We Know?" by the CFIDS Association of America with speakers Gudrun Lange and Suzanne Vernon, introduced by Kim McCleary
- 2014, Episode 70, ME/CFS Alert - Llewellyn King Interviews Dr. Suzanne Vernon
- 2015, Sleep and ME/CFS - Suzanne Vernon, PhD, A Bateman Horne Education Meeting
- 2015, [1]Spoonie Radio Episode 09 Guest - Dr. Suzanne Vernon Podcast and Full Text Transcript
- 2016, Precision Medicine for ME/CFS & Fibromyalgia
Studies and Articles[edit | edit source]
- 2003, Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution[8] - (Full Text)
- 2003, Integration of gene expression, clinical, and epidemiologic data to characterize Chronic Fatigue Syndrome[9] - (Full Text)
- 2004, Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome[10] - (Abstract)
- 2005, Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study[7]
- 2006, Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: Prospective cohort study[11] - (Abstract)
- 2006, Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr Virus[12] - (Full Text)
- 2008, Neuroendocrine and immune network remodeling in chronic fatigue syndrome: an exploratory analysis[13] - (Full Text)
- 2008, Evidence of inflammatory immune signaling in chronic fatigue syndrome: A pilot study of gene expression in peripheral blood.[14] - (Abstract)
- 2009, Transcriptional control of complement activation in an exercise model of chronic fatigue syndrome[15] - (Full text)
- 2012, Cytokine expression profiles of immune imbalance in post-mononucleosis chronic fatigue[16] -
- 2014, No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank[17] - (Full Text)
- 2014, Examining case definition criteria for chronic fatigue syndrome and myalgic encephalomyelitis[18] -
- 2015, Chronic fatigue syndrome versus systemic exertion intolerance disease][19] - (Abstract) -
- 2015, Comparing and contrasting consensus versus empirical domains[20] - (Abstract) -
- 2015, Changes in Gut and Plasma Microbiome following Exercise Challenge in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[21] - (Full Text)
- 2016, The utility of patient-reported outcome measures among patients with myalgic encephalomyelitis/chronic fatigue syndrome[22] - (Full Text)
- 2016, Tracking post-infectious fatigue in clinic using routine Lab tests[23] - (Full Text)
- 2016, Current therapeutic strategies for myalgic encephalomyelitis/chronic fatigue syndrome: results of an online survey[24] - (Abstract)
- 2016, Article - Uncovering Biomarkers– Fcg receptors in ME/CFS
- 2016, Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome[25] - (Full Text)
- 2017, Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[26] - (Full Text)
- 2017, Neural Consequences of Post-Exertion Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[27] - (Full Text) -
- 2018, A C-reactive protein response in patients with post-treatment Lyme Disease symptoms versus those with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[28] - (Abstract)
- 2018, Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome[29] - (Abstract)
- 2018, Letter - Markers of non-coeliac wheat sensitivity in patients with myalgic encephalomyelitis/chronic fatigue syndrome[30] - (Full Text)
- 2018, Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[31] - (Abstract)
- 2019, Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[32] - (Full text)
- 2020, Hemodynamics during the 10-minute NASA Lean Test: evidence of circulatory decompensation in a subset of ME/CFS patients[33] - (Full text)
Online presence[edit | edit source]
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- ↑ 1.0 1.1 "Suzanne D. Vernon, PhD". Bateman Horne Center. Retrieved February 2, 2019.
- ↑ http://www.thebiocollective.com/about-us/
- ↑ "Suzanne D. Vernon Steps Down from Scientific Director Post". Solve ME/CFS Initiative. April 8, 2015. Retrieved February 2, 2019.
- ↑ "Advancing Science: A Case for Hope, A Look Ahead". Solve ME/CFS Initiative. Retrieved June 25, 2019.
- ↑ https://www.linkedin.com/in/suzanne-d-vernon-phd-2743a617
- ↑ Grady, Denise (August 8, 2012). "Dr. William C. Reeves, Who Sought Cause of Fatigue Syndrome, Dies at 69". The New York Times. ISSN 0362-4331. Retrieved February 2, 2019.
- ↑ 7.0 7.1 Reeves, William C; Wagner, Dieter; Nisenbaum, Rosane; Jones, James F; Gurbaxani, Brian; Solomon, Laura; Papanicolaou, Dimitris A; Unger, Elizabeth R; Vernon, Suzanne D (December 2005). "Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study". BMC Medicine. 3: 19. doi:10.1186/1741-7015-3-19. ISSN 1741-7015.
- ↑ Reeves, W.C.; Lloyd, A.; Vernon, S.D.; Klimas, N.; Jason, L.A.; Bleijenberg, G.; Evengard, B.; White, P.D.; Nisenbaum, R.; Unger, E. (2003). "Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution". BMC Health Services Research. 3: 25. doi:10.1186/1472-6963-3-25.
- ↑ Whistler, Toni; Unger, Elizabeth R.; Nisenbaum, Rosane; Vernon, Suzanne D. (December 1, 2003). "Integration of gene expression, clinical, and epidemiologic data to characterize Chronic Fatigue Syndrome". Journal of Translational Medicine. 1: 10. doi:10.1186/1479-5876-1-10. ISSN 1479-5876. PMC 305360. PMID 14641939.
- ↑ Rajeevan, Mangalathu S.; Jones, James F.; Vernon, Suzanne D.; Unger, Elizabeth R.; Steinau, Martin (November 1, 2004). "Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome". Journal of Molecular Medicine. 82 (11): 750–755. doi:10.1007/s00109-004-0586-4. ISSN 1432-1440.
- ↑ Hickie, Ian; Davenport, Tracey; Wakefield, Denis; Vollmer-Conna, Ute; Cameron, Barbara; Vernon, Suzanne D; Reeves, William C; Lloyd, Andrew (September 16, 2006). "Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study". BMJ. 333 (7568): 575–. doi:10.1136/bmj.38933.585764.ae. PMC 1569956. PMID 16950834.
- ↑ Vernon, SD; Whistler, T; Cameron, B; Hickie, IB; Reeves, WC; Lloyd, A (2006). "Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr Virus". BMC Infectious Diseases. 6 (15). doi:10.1186/1471-2334-6-15. PMID 16448567.
- ↑ Fuite, Jim; Vernon, Suzanne; Broderick, Gordon (2008). "Neuroendocrine and immune network re-modeling in chronic fatigue syndrome: an exploratory analysis". Genomics. 92 (6): 393–9. doi:10.1016/j.ygeno.2008.08.008. PMID 18775774.
- ↑ Aspler, AL; Bolshin, C; Vernon, SD; Broderick, G (2008). "Evidence of inflammatory immune signaling in chronic fatigue syndrome: A pilot study of gene expression in peripheral blood". Behavioral and Brain Functions. 4: 44. doi:10.1186/1744-9081-4-44.
- ↑ Sorensen, Bristol; Jones, James F; Vernon, Suzanne D; Rajeevan, Mangalathu S (January 2009). "Transcriptional Control of Complement Activation in an Exercise Model of Chronic Fatigue Syndrome". Molecular Medicine. 15 (1–2): 34–42. doi:10.2119/molmed.2008.00098. PMC 2583111. PMID 19015737.
- ↑ Broderick, Gordon; Katz, Ben Z; Fernandes, Henrique; Fletcher, Mary Ann; Klimas, Nancy; Smith, Frederick A; O'Gorman, Maurice RG; Vernon, Suzanne D; Taylor, Renee (2012). "Cytokine expression profiles of immune imbalance in post-mononucleosis chronic fatigue". Journal of Translational Medicine. 10: 191. doi:10.1186/1479-5876-10-191.
- ↑ Irlbeck, David M.; Vernon, Suzanne D.; McCleary, K. Kimberly; Bateman, Lucinda; Klimas, Nancy G.; Lapp, Charles W.; Peterson, Daniel L.; Brown, James R.; Remlinger, Katja S.; Wilfret, David A.; Gerondelis, Peter (2014). "No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank". BMC Research Notes. 7: 461. doi:10.1186/1756-0500-7-461.
- ↑ Jason, Leonard A.; Sunnquist, Madison; Brown, Abigail; Evans, Meredyth; Vernon, Suzanne D.; Furst, Jacob D.; Simonis, Valerie (2014). "Examining case definition criteria for chronic fatigue syndrome and myalgic encephalomyelitis". Fatigue: Biomedicine, Health & Behavior. 2 (1): 40–56. doi:10.1080/21641846.2013.862993. PMC 3912876.
- ↑ Jason, L.A.; Sunnquist, M.; Brown, A.; Newton, J.L.; Strand, E.B.; Vernon, S.D. (2015). "Chronic fatigue syndrome versus systemic exertion intolerance disease". Fatigue: Biomedicine, Health & Behavior. 3 (3): 127–141. doi:10.1080/21641846.2015.1051291.
- ↑ Jason, LA; Kot, B; Sunnquist, M; Brown, A; Reed, J; Furst, J; Newton, JL; Strand, EB; Vernon, SD (2015). "Comparing and Contrasting Consensus versus Empirical Domains". Fatigue: biomedicine, health & behavior. 3 (2): 63–74. doi:10.1080/21641846.2015.1017344. PMID 26977374.
- ↑ Shukla, SK; Cook, DB; Meyer, J; Vernon, SD; Le, T; Clevidence, D; Robertson, CE; Schrodi, SJ; Yale, S; Frank, DN (2015). "Changes in Gut and Plasma Microbiome following Exercise Challenge in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)". PLoS One. 10 (12): e0145453. doi:10.1371/journal.pone.0145453. PMC 468420.
- ↑ Murdock, KW; Wang, XS; Shi, Q; Cleeland, CS; Fagundes, CP; Vernon, Suzanne D. (2016). "The utility of patient-reported outcome measures among patients with myalgic encephalomyelitis/chronic fatigue syndrome". Quality of Life Research. 26: 913–921. doi:10.1007/s11136-016-1406-3. PMC 5336422. PMID 27600520.
- ↑ Harvey, Jeanna M.; Broderick, Gordon; Bowie, Alanna; Barnes, Zachary M.; Katz, Ben Z.; O'Gorman, Maurice R.G.; Vernon, Suzanne D.; Fletcher, Mary Ann; Klimas, Nancy G. (April 26, 2016). "Tracking post-infectious fatigue in clinic using routine Lab tests". BMC Pediatrics. 15: 54. doi:10.1186/s12887-016-0596-8. ISSN 1471-2431. PMC 4847210. PMID 27118537.
- ↑ Deftereos, S. N.; Vernon, S. D.; Persidis, A. (2016). "Current therapeutic strategies for myalgic encephalomyelitis/chronic fatigue syndrome: results of an online survey". Fatigue: Biomedicine, Health & Behavior. 4 (1): 39–51. doi:10.1080/21641846.2015.1126025.
- ↑ Landi, Abdolamir; Broadhurst, David; Vernon, Suzanne D.; Tyrrell, D. Lorne J.; Houghton, Michael (February 2016). "Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome". Cytokine. 78: 27–36. doi:10.1016/j.cyto.2015.11.018.
- ↑ de Vega, Wilfred C.; Herrera, Santiago; Vernon, Suzanne D.; McGowan, Patrick O. (2017). "Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)". BMC Med Genomics. 10: 11. doi:10.1186/s12920-017-0248-3. PMC 5324230.
- ↑ Cook, Dane B.; Light, Alan R.; Light, Kathleen C.; Broderick, Gordon; Shields, Morgan R.; Dougherty, Ryan J.; Meyer, Jacob D.; VanRiper, Stephanie; Stegner, Aaron J.; Ellingson, Laura D.; Vernon, Suzanne D. (2017). "Neural Consequences of Post-Exertion Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Brain, Behavior, and Immunity. 62: 87–99. doi:10.1016/j.bbi.2017.02.009.
- ↑ Uhde, M; Indart, AC; Fallon, BA; Wormser, GP; Marques, AR; Vernon, SD; Alaedini, A (2018). "C-reactive protein response in patients with post-treatment Lyme Disease symptoms versus those with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Clin Infect Dis. 67 (8): 1309–1310. doi:10.1093/cid/ciy299. PMC 6160605. PMID 29741589.
- ↑ de Vega, Wilfred C.; Erdman, Lauren; Vernon, Suzanne D.; Goldenberg, Anna; McGowan, Patrick O. (2018). "Integration of DNA methylation & health scores identifies subtypes in myalgic encephalomyelitis/chronic fatigue syndrome". Epigenomics. 10 (5): 539–557. doi:10.2217/epi-2017-0150.
- ↑ Uhde, M; Indart, AC; Yu, XB; Jang, SS; De Giorgio, R; Green, PHR; Volta, U; Vernon, SD; Alaedini, A (2018). "Markers of non-coeliac wheat sensitivity in patients with myalgic encephalomyelitis/chronic fatigue syndrome". Gut. 68: 377–378. doi:10.1136/gutjnl-2018-316133.
- ↑ Herrera, S; de Vega, WC; Ashbrook, D; Vernon, SD; McGowan, PO (December 2018). "Genome-epigenome interactions associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Epigenetics. 13 (12): 1174–1190. doi:10.1080/15592294.2018.1549769. PMID 30516085.
- ↑ Karhan, Ece; Gunter, Courtney L; Ravanmehr, Vida; Horne, Meghan; Kozhaya, Lina; Renzullo, Stephanie; Placek, Lindsey; George, Joshy; Robinson, Peter N; Vernon, Suzanne D.; Bateman, Lucinda; Unutmaz, Derya (December 26, 2019). "Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)". biorxiv. doi:10.1101/2019.12.23.887505.
- ↑ Lee, Jihyun; Vernon, Suzanne D.; Jeys, Patricia; Ali, Weam; Campos, Andrea; Unutmaz, Derya; Yellman, Brayden; Bateman, Lucinda (December 2020). "Hemodynamics during the 10-minute NASA Lean Test: evidence of circulatory decompensation in a subset of ME/CFS patients". Journal of Translational Medicine. 18 (1): 314. doi:10.1186/s12967-020-02481-y. ISSN 1479-5876. PMC 7429890. PMID 32799889.