Gudrun Lange, PhD, is a clinical neuropsychologist who works with Dr. Benjamin Natelson at the Pain & Fatigue Study Center, New York, New York. There she heads studies on brain fog in chronic fatigue syndrome and fibromyalgia.
Committees and Boards[edit | edit source]
- Dec 2017 - Dec 2021, a voting member of the Chronic Fatigue Syndrome Advisory Committee for the U.S. Department of Health and Human Services
- 2017-2018, Chair of the CNS Imaging subgroup of the Neurologic/Cognitive/CNS Imaging Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.
Notable studies[edit | edit source]
- 2001, Health-Related Personality Variables in Chronic Fatigue Syndrome and Multiple Sclerosis(Abstract)
- 2002, A status report on chronic fatigue syndrome(Full Text)
- 2004, Cognitive Function Index for Patients with Chronic Fatigue Syndrome
- 2005, Objective evidence of cognitive complaints in Chronic Fatigue Syndrome: a BOLD fMRI study of verbal working memory(Abstract)
- 2013, Attention network test: assessment of cognitive function in chronic fatigue syndrome
- 2011, Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial
- 2015, Effect of Milnacipran Treatment on Ventricular Lactate in Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Trial(Full Text)
- 2017, Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study(Full Text)
- 2017, Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity(Full Text)
Clinic location[edit | edit source]
Talks and interviews[edit | edit source]
- 2009, 9th International IACFS/ME Research and Clinical Conference: Talk Title - Assessing ME/CFS Brain Functioning
- 11 April 2012, "Cognition & CFS: What Do We Know?" by the CFIDS Association of America with speakers Gudren Lange and Suzanne Vernon, introduced by Kim McCleary
Online presence[edit | edit source]
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- "Pain and Fatigue Study Center". www.painandfatigue.com. Retrieved Aug 14, 2018.
- (ASH), Assistant Secretary for Health (Jul 26, 2007). "Roster". HHS.gov. Retrieved Aug 14, 2018.
- "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved Oct 11, 2019.
- Johnson, Susan K.; Lange, Gudrun; Tiersky, Lana; Deluca, John; Natelson, Benjamin H. (Jan 2001). "Health-Related Personality Variables in Chronic Fatigue Syndrome and Multiple Sclerosis". Journal of Chronic Fatigue Syndrome. 8 (3-4): 41–52. doi:10.1300/j092v08n03_05. ISSN 1057-3321.
- Natelson, Benjamin H; Lange, Gudrun (2002), "A status report on chronic fatigue syndrome", Environmental Health Perspectives, 110 (Supp 4): 673–677
- Brimacombe, Michael; Lange, Gudrun; Bisuchio, Kim; Ciccone, Donald S.; Natelson, Benjamin (Jan 2004). "Cognitive Function Index for Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 12 (4): 3–23. doi:10.1300/j092v12n04_02. ISSN 1057-3321.
- Lange, G; Steffener, J; Cook, DB; Bly, BM; Christodoulou, C; Liu, WC; Deluca, J; Natelson, BH (2005), "Objective evidence of cognitive complaints in Chronic Fatigue Syndrome: a BOLD fMRI study of verbal working memory", NeuroImage, 26 (2): 513-24, doi:10.1016/j.neuroimage.2005.02.011, PMID 15907308
- Togo, Fumiharu; Lange, Gudrun; Natelson, Benjamin H.; Quigley, Karen S. (Sep 24, 2013). "Attention network test: Assessment of cognitive function in chronic fatigue syndrome". Journal of Neuropsychology. 9 (1): 1–9. doi:10.1111/jnp.12030. ISSN 1748-6645. PMID 24112872.
- Lange, Gudrun; Janal, Malvin N.; Maniker, Allen; Fitzgibbons, Jennifer; Fobler, Malusha; Cook, Dane; Natelson, Benjamin H. (September 2011), "Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial", ain Medicine (Malden, Mass.), 12 (9): 1406–1413, doi:10.1111/j.1526-4637.2011.01203.x, ISSN 1526-4637, PMID 21812908
- Natelson, B.H.; Vu, D.; Mao, X.; Weiduschat, N.; Togo, F.; Lange, G.; Blate, M.; Kang, G.; Coplan, J.D.; Shungu, D.C. (2015). "Effect of milnacipran treatment on ventricular lactate in fibromyalgia: A randomized, double-blind, placebo-controlled trial" (PDF). Journal of Pain. 16 (11): 1211–1219. doi:10.1016/j.jpain.2015.08.004.
- Unger, Elizabeth R.; Lin, Jin-Mann S.; Tian, Hao; Natelson, Benjamin H; Lange, Gudrun; Vu, Diana; Blate, Michelle; Klimas, Nancy G.; Balbin, Elizabeth G.; Bateman, Lucinda; Allen, Ali; Lapp, Charles W.; Springs, Wendy; Kogelnik, Andreas M.; Phan, Catrina C.; Danver, Joan; Podell, Richard N.; Fitzpatrick, Trisha; Peterson, Daniel L.; Gottschalk, C. Gunnar; Rajeevan, Mangalathu S.; MCAM Study Group (2017), "Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.", American Journal of Epidemiology, 1–10, doi:10.1093/aje/kwx029
- Natelson, Benjamin; Mao, Xiangling; Stegner, Aaron J; Lange, Gudrun; Vu, Diana; Blate, Michelle; Kang, Guoxin; Soto, Eli; Kapusuz, Tolga; Shungu, Dikoma C (2017), "Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity" (PDF), Journal of the Neurological Sciences, 375: 411-416, doi:10.1016/j.jns.2017.02.046
Cognition - Thought processes, including attention, reasoning, and memory.
Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.