Benjamin Natelson
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Dr. Benjamin Natelson, is a neurologist with post-doctoral training in Behavioral Medicine. He is head of the Pain and Fatigue Study Center in New York City which specializes in treating and researching ME/CFS|myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), and severe pain and fatigue illnesses. He is, also, an Emeritus Professor of Neurology and Neurosciences at Rutgers and Professor of Neurology at the Icahn School of Medicine at Mt. Sinai.[1]
Awards[edit | edit source]
- 2009, Rudy Perpich Senior Lectureship Award, presented to a distinguished CFS/FM scientist, physician or healthcare worker awarded by IACFS/ME[2]
Education[edit | edit source]
- Medical degree: University of Pennsylvania in Philadelphia
- Neurology Residence: The Albert Einstein College of Medicine in the Bronx
- Post-doctoral training in Behavioral Medicine: Cornell University's New York Hospital and the Walter Reed Institute of Research (formerly) in Washington, DC
Committees[edit | edit source]
Board of Directors IACFSME[edit | edit source]
- 2001-2003, He served as past President of the Board of Directors of the International Association for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis from 2001-2003.[3]
Medscape Continuing Medicine Education[edit | edit source]
- 2013, A Case-Based Approach to Chronic Fatigue Syndrome was a Medscape Continuing Medicine Education program co-authored by Dr Lisa Corbin, Dr Anthony Komaroff, Dr Benjamin Natelson, and Dr Peter Rowe.[4]
IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]
- 2015, Dr. Natelson was one of the experts on the "Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome" that was convened for the 2015 Institute of Medicine report.[5]
ME/CFS Common Data Element (CDE) Project[edit | edit source]
- 2018, Member of the Neurologic/Cognitive/CNS Imaging Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[6]
Notable studies[edit | edit source]
- A more complete list of Dr. Natelson's ME/CFS and FM research studies can be found at The Pain and Fatigue Study Center's Scientific Publications Link.
- 1998, Measurement of CO2 in Chronic Fatigue Syndrome Patients[7] - (Abstract)
- 1998, Relation between neuropsychological impairment and functional disability in patients with chronic fatigue syndrome[8] (Full Article)
- 1999, Impaired oxygen delivery to muscle in chronic fatigue syndrome[9] - (Full Article)
- 2000, Psychiatric Comorbidity and Somatic Distress in Sudden and Gradual Onset Chronic Fatigue Syndrome[10] - (Full Article)
- 2001, Health-Related Personality Variables in Chronic Fatigue Syndrome and Multiple Sclerosis[11] - (Abstract)
- 2001, Detection of Immunologically Significant Factors for Chronic Fatigue Syndrome Using Neural-Network Classifiers[12] - (Full Text)
- 2001, Chronic Fatigue Syndrome[13] - (Abstract)
- 2003, Perceived exertion in fatiguing illness: civilians with chronic fatigue syndrome[14] - (Abstract)
- 2004, Cognitive Function Index for Patients with Chronic Fatigue Syndrome[15] - (Abstract)
- 2004, Muscle metabolism with blood flow restriction in chronic fatigue syndrome[16] - (Full Text)
- 2005, Objective evidence of cognitive complaints in Chronic Fatigue Syndrome: a BOLD fMRI study of verbal working memory[17] - (Abstract)
- 2006, The influence of aerobic fitness and fibromyalgia on cardiorespiratory and perceptual responses to exercise in patients with chronic fatigue syndrome[18] - (Full Text)
- 2007, Hypocapnia is a biological marker for orthostatic intolerance in some patients with chronic fatigue syndrome[19] - (Full Text)
- 2010, Sleep is not disrupted by exercise in patients with chronic fatigue syndromes[20] - (Full Article)
- 2010, Cytokines across the night in chronic fatigue syndrome with and without fibromyalgia[21] - (Full Article)
- 2011, Distinct Cerebrospinal Fluid Proteomes Differentiate Post-Treatment Lyme Disease from Chronic Fatigue Syndrome[22] - (Full Article)
- 2011, Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial[23]
- 2012, Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology[24] - (Full Text)
- 2013, Is chronic fatigue syndrome the same illness as fibromyalgia: evaluating the ‘single syndrome’ hypothesis[25] - (Full Text)
- 2013, Attention network test: assessment of cognitive function in chronic fatigue syndrome[26]
- 2013, Exercise and sleep deprivation do not change cytokine expression levels in patients with chronic fatigue syndrome[27] - (Full Article)
- 2015, Effect of Milnacipran Treatment on Ventricular Lactate in Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Trial[28](Full Text)
- 2015, Chronic fatigue syndrome and fibromyalgia in diagnosed sleep disorders: a further test of the 'unitary' hypothesis.[29] - (Full Text)
- 2017, Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study[30] - (Full Text)
- 2017, Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia[31] - (Full text)
- 2017, Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity[32] - (Full Text)
- 2018, Balance deficits in Chronic Fatigue Syndrome with and without fibromyalgia[33] - (Abstract)
- 2019, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences[34]
- 2019, The effect of comorbid medical and psychiatric diagnoses on chronic fatigue syndrome[35] - (Abstract)
Interviews & talks[edit | edit source]
Clinical location[edit | edit source]
- Pain and Fatigue Study Center
- Phillips Ambulatory Care Center, Suite 4K
- Beth Israel Medical Center
- 10 Union Square East
- New York, NY 10003-3314
- 212-844-6665
Online presence[edit | edit source]
Books[edit | edit source]
- 1998, Facing and Fighting Fatigue: A Practical Approach
- 2007, Your Symptoms Are Real: What to Do When Your Doctor Says Nothing Is Wrong
- 2008, Fatigue Science for Human Health, edited by Yatanabe, Y., Evengard, B., Natelson, B.H., Jason, L.A., & Kuratsune, H.
References[edit | edit source]
- ↑ "Pain and Fatigue Study Center - Welcome". Retrieved April 23, 2020.
- ↑ "IACFS/ME Awardees". IACFS/ME. Retrieved April 23, 2020.
- ↑ http://iacfsme.org/Organization/Committees-of-the-IACFS-ME.aspx
- ↑ Corbin, Lisa; Komaroff, Anthony L.; Natelson Peter C. Rowe, Benjamin H.; Rowe, Peter. "A Case-Based Approach to Chronic Fatigue Syndrome". Medscape. Retrieved October 11, 2019.
- ↑ http://www.ncbi.nlm.nih.gov/books/NBK284904/
- ↑ "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
- ↑ Marc H. Lavietes, Michael T. Bergen, and Benjamin H. Natelson. (1998). Measurement of CO2 in Chronic Fatigue Syndrome Patients. Journal of Chronic Fatigue Syndrome, Vol. 4, Iss. 3, pp. 3-11 . http://dx.doi.org/10.1300/J092v04n03_02
- ↑ Christodoulou, C., DeLuca, J., Lange, G., Johnson, S., Sisto, S. A., Korn, L., & Natelson, B. (1998). Relation between neuropsychological impairment and functional disability in patients with chronic fatigue syndrome. Journal of Neurology, Neurosurgery, and Psychiatry, 64(4), 431–434.
- ↑ Kevin K. McCully and Benjamin H. Natelson. (1999). Impaired oxygen delivery to muscle in chronic fatigue syndrome. Clinical Science (London). 1999 Nov;97(5):603-8. PMID: 10545311
- ↑ Cukor, Daniel; Sky, Lana Tier; Natelson, Benjamin H. (2000), "Psychiatric Comorbidity and Somatic Distress in Sudden and Gradual Onset Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 7 (4): 33–44, doi:10.1300/J092v07n04_04
- ↑ Johnson, Susan K.; Lange, Gudrun; Tiersky, Lana; Deluca, John; Natelson, Benjamin H. (2001). "Health-Related Personality Variables in Chronic Fatigue Syndrome and Multiple Sclerosis". Journal of Chronic Fatigue Syndrome. 8 (3–4): 41-52. doi:10.1300/J092v08n03_05.
- ↑ Hanson, S.J.; Gause, W.; Natelson, B. (May 1, 2001). "Detection of Immunologically Significant Factors for Chronic Fatigue Syndrome Using Neural-Network Classifiers". Clinical and Diagnostic Laboratory Immunology. 8 (3): 658–662. doi:10.1128/CDLI.8.3.658-662.2001. ISSN 1556-6811. PMID 11329477.
- ↑ Natelson, BH (May 2001). "Chronic Fatigue Syndrome". JAMA. 285 (20): 2557–2559. Retrieved May 7, 2020.
- ↑ Cook, DB; Nagelkirk, PR; Peckerman, A; Poluri, A; Lamanca, JJ; Natelson, BH (2003), "Perceived exertion in fatiguing illness: civilians with chronic fatigue syndrome", Med Sci Sports Exerc., 35 (4): 563-8, doi:10.1249/01.MSS.0000058360.61448.6C, PMID 12673137
- ↑ Michael Brimacombe, Gudrun Lange, Kim Bisuchio, Donald S. Ciccone & Benjamin Natelson. (2004). Cognitive Function Index for Patients with Chronic Fatigue Syndrome. Journal of Chronic Fatigue Syndrome, Vol. 12, Iss. 4, pp. 3-23. http://dx.doi.org/10.1300/J092v12n04_02
- ↑ McCully, Kevin K.; Smith, Sinclair; Rajaei, Sheeva; Leigh, John S.; Natelson, Benjamin H. (March 2004). "Muscle metabolism with blood flow restriction in chronic fatigue syndrome". Journal of Applied Physiology (Bethesda, Md.: 1985). 96 (3): 871–878. doi:10.1152/japplphysiol.00141.2003. ISSN 8750-7587. PMID 14578362.
- ↑ Cook, DB; Nagelkirk, PR; Peckerman, A; Poluri, A; Mores, J; Natelson, BH (2005), "Exercise and cognitive performance in chronic fatigue syndrome", Medicine and Science in Sports and Exercise, 37 (9): 1460–7, PMID 16177595
- ↑ Cook, Dane B.; Nagelkirk, Paul R.; Poluri, Ashok; Mores, John; Natelson, Benjamin H. (October 2006). "The influence of aerobic fitness and fibromyalgia on cardiorespiratory and perceptual responses to exercise in patients with chronic fatigue syndrome". Arthritis & Rheumatism. 54 (10): 3351–3362. doi:10.1002/art.22124. ISSN 0004-3591.
- ↑ Natelson, Benjamin H; Intriligator, Roxann; Cherniack, Neil S; Chandler, Helena K; Stewart, Julian M (2007). "Hypocapnia is a biological marker for orthostatic intolerance in some patients with chronic fatigue syndrome". Dynamic Medicine. 6 (1): 2. doi:10.1186/1476-5918-6-2. ISSN 1476-5918. PMID 17263876.
- ↑ Togo, F; Natelson, BH; Cherniack, NS; Rapoport, DM; Klapholz, M; Cook, DB (2010), "Sleep is not disrupted by exercise in patients with chronic fatigue syndrome", Medicine and Science in Sports and Exercise, 42 (1): 16-22, doi:10.1249/MSS.0b013e3181b11bc7, PMID 20010134
- ↑ Nakamura, T; Schwander, S; Donnelly, R; Ortega, F; Togo, F; Broderick, G; Yamamoto, Y; Cherniack, NS; Rapoport, D; Natelson, BH (2010), "Cytokines across the Night in Chronic Fatigue Syndrome with and without Fibromyalgia", Clinical and Vaccine Immunology, 17 (4): 582–587, doi:10.1128/CVI.00379-09
- ↑ Schutzer, Steven E; Angel, Thomas E.; Liu, Tao; Schepmoes, Athena A.; Clauss, Therese R.; Adkins, Joshua N.; Camp, David G.; Holland, Bart K.; Bergquist, Jonas; Coyle, Patricia K.; Smith, Richard D.; Fallon, Brian A.; Natelson, Benjamin (2011), "Distinct Cerebrospinal Fluid Proteomes Differentiate Post-Treatment Lyme Disease from Chronic Fatigue Syndrome", PLOS ONE, 6 (2), doi:10.1371/journal.pone.0017287
- ↑ Lange, Gudrun; Janal, Malvin N.; Maniker, Allen; Fitzgibbons, Jennifer; Fobler, Malusha; Cook, Dane; Natelson, Benjamin H. (September 2011), "Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial", Pain Medicine (Malden, Mass.), 12 (9): 1406–1413, doi:10.1111/j.1526-4637.2011.01203.x, ISSN 1526-4637, PMID 21812908
- ↑ Shungu, Dikoma C.; Weiduschat, Nora; Murrough, James W.; Mao, Xiangling; Pillemer, Sarah; Dyke, Jonathan P.; Medow, Marvin S.; Natelson, Benjamin H.; Stewart, Julian M. (January 27, 2012). "Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology". NMR in Biomedicine. 25 (9): 1073–1087. doi:10.1002/nbm.2772. ISSN 0952-3480. PMID 22281935.
- ↑ Abbi, B.; Natelson, B.H. (January 1, 2013). "Is chronic fatigue syndrome the same illness as fibromyalgia: evaluating the 'single syndrome' hypothesis". QJM: An International Journal of Medicine. 106 (1): 3–9. doi:10.1093/qjmed/hcs156. ISSN 1460-2725. PMID 22927538.
- ↑ Togo, F., G. Lange, B.H. Natelson, and K.S. Quigley. Attention network test: assessment of cognitive function in chronic fatigue syndrome. Journal of Neuropsychology, 2013 Sep 24. doi: 10.1111/jnp.12030.
- ↑ Nakamura, T; Schwander, S; Donnelly, R; Cook, DB; Ortega, F; Togo, F; Yamamoto, Y; Cherniack, NS; Klapholz, M; Rapoport, D; Natelson, BH (2013), "Exercise and sleep deprivation do not change cytokine expression levels in patients with chronic fatigue syndrome", Clinical and Vaccine Immunology, 20 (11): 1736–1742, doi:10.1128/CVI.00527-13
- ↑ Natelson, B.H.; Vu, D.; Mao, X.; Weiduschat, N.; Togo, F.; Lange, G.; Blate, M.; Kang, G.; Coplan, J.D.; Shungu, D.C. (2015). "Effect of milnacipran treatment on ventricular lactate in fibromyalgia: A randomized, double-blind, placebo-controlled trial" (PDF). Journal of Pain. 16 (11): 1211–1219. doi:10.1016/j.jpain.2015.08.004.
- ↑ Pejovic, Slobodanka; Natelson, Benjamin H; Basta, Maria; Fernandez-Mendoza, Julio; Mahr, Fauzia; Vgontzas, Alexandros N (April 12, 2015). "Chronic fatigue syndrome and fibromyalgia in diagnosed sleep disorders: a further test of the 'unitary' hypothesis". BMC Neurology. 15 (1). doi:10.1186/s12883-015-0308-2. ISSN 1471-2377. PMID 25884538.
- ↑ Unger, Elizabeth R.; Lin, Jin-Mann S.; Tian, Hao; Natelson, Benjamin H; Lange, Gudrun; Vu, Diana; Blate, Michelle; Klimas, Nancy G.; Balbin, Elizabeth G.; Bateman, Lucinda; Allen, Ali; Lapp, Charles W.; Springs, Wendy; Kogelnik, Andreas M.; Phan, Catrina C.; Danver, Joan; Podell, Richard N.; Fitzpatrick, Trisha; Peterson, Daniel L.; Gottschalk, C. Gunnar; Rajeevan, Mangalathu S.; MCAM Study Group (2017), "Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.", American Journal of Epidemiology, 185 (8): 617–626, doi:10.1093/aje/kwx029, PMC 5565838, PMID 28338983
- ↑ Natelson, Benjamin; Vu, Diana; Coplan, Jeremy D.; Mao, Xiangling; Blate, Michelle; Kang, Guoxin; Soto, Eli; Tolga Kapusuz, Tolga; Shungu, Dikoma (2017), "Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia", Fatigue: Biomedicine, Health & Behavior, 5 (1): 15–20, doi:10.1080/21641846.2017.1280114, PMC 5754037, PMID 29308330
- ↑ Natelson, Benjamin; Mao, Xiangling; Stegner, Aaron J; Lange, Gudrun; Vu, Diana; Blate, Michelle; Kang, Guoxin; Soto, Eli; Kapusuz, Tolga; Shungu, Dikoma C (2017), "Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity", Journal of the Neurological Sciences, 375: 411-416, doi:10.1016/j.jns.2017.02.046
- ↑ Serrador, Jorge M.; Quigley, Karen; Zhao, Caixiab; Findley, Thomas; Natelson, Benjamin H. (2018), "Balance deficits in Chronic Fatigue Syndrome with and without fibromyalgia", NeuroRehabilitation, 42 (2): 235–246, doi:10.3233/NRE-172245
- ↑ Natelson, Benjamin H. (February 2019). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences". Clinical Therapeutics. doi:10.1016/j.clinthera.2018.12.016.
- ↑ Natelson, Benjamin H.; Lin, Jin-Mann S.; Lange, Gudrun; Khan, Sarah; Stegner, Aaron (November 2019). "The effect of comorbid medical and psychiatric diagnoses on chronic fatigue syndrome". Annals of Medicine. doi:10.1080/07853890.2019.1683601.
