Benjamin Natelson

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Source: Pain and Fatigue Study Center

Dr. Benjamin Natelson, is a Neurologist with post-doctoral training in Behavioral Medicine. He is head of the Pain and Fatigue Study Center in New York City which specializes in treating and researching myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), and severe pain and fatigue illnesses. He is, also, an Emeritus Professor of Neurology and Neurosciences at Rutgers and Professor of Neurology at the Icahn School of Medicine at Mt. Sinai.

Awards[edit | edit source]

  • 2009, Rudy Perpich Senior Lectureship Award, presented to a distinguished CFS/FM scientist, physician or healthcare worker awarded by IACFS/ME[1]

Education[edit | edit source]

  • Medical degree: University of Pennsylvania in Philadelphia
  • Neurology Residence: The Albert Einstein College of Medicine in the Bronx
  • Post-doctoral training in Behavioral Medicine: Cornell University's New York Hospital and the Walter Reed Institute of Research (formerly) in Washington, DC

Committees[edit | edit source]

Board of Directors IACFSME[edit | edit source]

Medscape Continuing Medicine Education[edit | edit source]

IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]

  • 2015, Dr. Natelson was one of the experts on the "Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome" that was convened for the 2015 Institute of Medicine report.[4]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Notable studies[edit | edit source]

A more complete list of Dr. Natelson's ME/CFS and FM research studies can be found at The Pain and Fatigue Study Center's Scientific Publications Link.

Interviews & talks[edit | edit source]

Clinical location[edit | edit source]

Pain and Fatigue Study Center
Phillips Ambulatory Care Center, Suite 4K
Beth Israel Medical Center
10 Union Square East
New York, NY 10003-3314

Online presence[edit | edit source]

Books[edit | edit source]

References[edit | edit source]

  3. Corbin, Lisa; Komaroff, Anthony L.; Natelson Peter C. Rowe, Benjamin H.; Rowe, Peter. "A Case-Based Approach to Chronic Fatigue Syndrome". Medscape. Retrieved Oct 11, 2019. 
  5. "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved Oct 11, 2019. 
  6. Marc H. Lavietes, Michael T. Bergen, and Benjamin H. Natelson. (1998). Measurement of CO2 in Chronic Fatigue Syndrome Patients. Journal of Chronic Fatigue Syndrome, Vol. 4, Iss. 3, pp. 3-11 .
  7. Christodoulou, C., DeLuca, J., Lange, G., Johnson, S., Sisto, S. A., Korn, L., & Natelson, B. (1998). Relation between neuropsychological impairment and functional disability in patients with chronic fatigue syndrome. Journal of Neurology, Neurosurgery, and Psychiatry, 64(4), 431–434.
  8. Kevin K. McCully and Benjamin H. Natelson. (1999). Impaired oxygen delivery to muscle in chronic fatigue syndrome. Clinical Science (London). 1999 Nov;97(5):603-8. PMID: 10545311
  9. Cukor, Daniel; Sky, Lana Tier; Natelson, Benjamin H. (2000), "Psychiatric Comorbidity and Somatic Distress in Sudden and Gradual Onset Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 7 (4): 33-44, doi:10.1300/J092v07n04_04 
  10. Johnson, Susan K.; Lange, Gudrun; Tiersky, Lana; Deluca, John; Natelson, Benjamin H. (2001). "Health-Related Personality Variables in Chronic Fatigue Syndrome and Multiple Sclerosis". Journal of Chronic Fatigue Syndrome. 8 (3-4): 41-52. doi:10.1300/J092v08n03_05. 
  11. Hanson, S. J.; Gause, W.; Natelson, B. (May 1, 2001). "Detection of Immunologically Significant Factors for Chronic Fatigue Syndrome Using Neural-Network Classifiers". Clinical and Diagnostic Laboratory Immunology. 8 (3): 658–662. doi:10.1128/CDLI.8.3.658-662.2001. ISSN 1556-6811. PMID 11329477. 
  12. Cook, DB; Nagelkirk, PR; Peckerman, A; Poluri, A; Lamanca, JJ; Natelson, BH (2003), "Perceived exertion in fatiguing illness: civilians with chronic fatigue syndrome", Med Sci Sports Exerc., 35 (4): 563-8., doi:10.1249/01.MSS.0000058360.61448.6C, PMID 12673137 
  13. Michael Brimacombe, Gudrun Lange, Kim Bisuchio, Donald S. Ciccone & Benjamin Natelson. (2004). Cognitive Function Index for Patients with Chronic Fatigue Syndrome. Journal of Chronic Fatigue Syndrome, Vol. 12, Iss. 4, pp. 3-23.
  14. McCully, Kevin K.; Smith, Sinclair; Rajaei, Sheeva; Leigh, John S.; Natelson, Benjamin H. (Mar 2004). "Muscle metabolism with blood flow restriction in chronic fatigue syndrome". Journal of Applied Physiology (Bethesda, Md.: 1985). 96 (3): 871–878. doi:10.1152/japplphysiol.00141.2003. ISSN 8750-7587. PMID 14578362. 
  15. Cook, DB; Nagelkirk, PR; Peckerman, A; Poluri, A; Mores, J; Natelson, BH (2005), "Exercise and cognitive performance in chronic fatigue syndrome", Medicine and Science in Sports and Exercise, 37 (9): 1460-7, PMID 16177595 
  16. Cook, Dane B.; Nagelkirk, Paul R.; Poluri, Ashok; Mores, John; Natelson, Benjamin H. (Oct 2006). "The influence of aerobic fitness and fibromyalgia on cardiorespiratory and perceptual responses to exercise in patients with chronic fatigue syndrome". Arthritis & Rheumatism. 54 (10): 3351–3362. doi:10.1002/art.22124. ISSN 0004-3591. 
  17. Natelson, Benjamin H; Intriligator, Roxann; Cherniack, Neil S; Chandler, Helena K; Stewart, Julian M (2007). "Hypocapnia is a biological marker for orthostatic intolerance in some patients with chronic fatigue syndrome". Dynamic Medicine. 6 (1): 2. doi:10.1186/1476-5918-6-2. ISSN 1476-5918. PMID 17263876. 
  18. Togo, F; Natelson, BH; Cherniack, NS; Rapoport, DM; Klapholz, M; Cook, DB (2010), "Sleep is not disrupted by exercise in patients with chronic fatigue syndrome", Medicine and Science in Sports and Exercise, 42 (1): 16-22, doi:10.1249/MSS.0b013e3181b11bc7, PMID 20010134 
  19. Nakamura, T; Schwander, S; Donnelly, R; Ortega, F; Togo, F; Broderick, G; Yamamoto, Y; Cherniack, NS; Rapoport, D; Natelson, BH (2010), "Cytokines across the Night in Chronic Fatigue Syndrome with and without Fibromyalgia", Clinical and Vaccine Immunology, 17 (4): 582–587, doi:10.1128/CVI.00379-09 
  20. Schutzer, Steven E; Angel, Thomas E.; Liu, Tao; Schepmoes, Athena A.; Clauss, Therese R.; Adkins, Joshua N.; Camp, David G.; Holland, Bart K.; Bergquist, Jonas; Coyle, Patricia K.; Smith, Richard D.; Fallon, Brian A.; Natelson, Benjamin (2011), "Distinct Cerebrospinal Fluid Proteomes Differentiate Post-Treatment Lyme Disease from Chronic Fatigue Syndrome", PLOS ONE, 6 (2), doi:10.1371/journal.pone.0017287 
  21. Lange, Gudrun; Janal, Malvin N.; Maniker, Allen; Fitzgibbons, Jennifer; Fobler, Malusha; Cook, Dane; Natelson, Benjamin H. (September 2011), "Safety and efficacy of vagus nerve stimulation in fibromyalgia: a phase I/II proof of concept trial", Pain Medicine (Malden, Mass.), 12 (9): 1406–1413, doi:10.1111/j.1526-4637.2011.01203.x, ISSN 1526-4637, PMID 21812908 
  22. Shungu, Dikoma C.; Weiduschat, Nora; Murrough, James W.; Mao, Xiangling; Pillemer, Sarah; Dyke, Jonathan P.; Medow, Marvin S.; Natelson, Benjamin H.; Stewart, Julian M. (Jan 27, 2012). "Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology". NMR in Biomedicine. 25 (9): 1073–1087. doi:10.1002/nbm.2772. ISSN 0952-3480. PMID 22281935. 
  23. Abbi, B.; Natelson, B. H. (Jan 1, 2013). "Is chronic fatigue syndrome the same illness as fibromyalgia: evaluating the 'single syndrome' hypothesis". QJM: An International Journal of Medicine. 106 (1): 3–9. doi:10.1093/qjmed/hcs156. ISSN 1460-2725. PMID 22927538. 
  24. Togo, F., G. Lange, B.H. Natelson, and K.S. Quigley. Attention network test: assessment of cognitive function in chronic fatigue syndrome. Journal of Neuropsychology, 2013 Sep 24. doi: 10.1111/jnp.12030.
  25. Nakamura, T; Schwander, S; Donnelly, R; Cook, DB; Ortega, F; Togo, F; Yamamoto, Y; Cherniack, NS; Klapholz, M; Rapoport, D; Natelson, BH (2013), "Exercise and sleep deprivation do not change cytokine expression levels in patients with chronic fatigue syndrome", Clinical and Vaccine Immunology, 20 (11): 1736-1742, doi:10.1128/CVI.00527-13 
  26. Natelson, B.H.; Vu, D.; Mao, X.; Weiduschat, N.; Togo, F.; Lange, G.; Blate, M.; Kang, G.; Coplan, J.D.; Shungu, D.C. (2015). "Effect of milnacipran treatment on ventricular lactate in fibromyalgia: A randomized, double-blind, placebo-controlled trial" (PDF). Journal of Pain. 16 (11): 1211–1219. doi:10.1016/j.jpain.2015.08.004. 
  27. Pejovic, Slobodanka; Natelson, Benjamin H; Basta, Maria; Fernandez-Mendoza, Julio; Mahr, Fauzia; Vgontzas, Alexandros N (Apr 12, 2015). "Chronic fatigue syndrome and fibromyalgia in diagnosed sleep disorders: a further test of the 'unitary' hypothesis". BMC Neurology. 15 (1). doi:10.1186/s12883-015-0308-2. ISSN 1471-2377. PMID 25884538. 
  28. Unger, Elizabeth R.; Lin, Jin-Mann S.; Tian, Hao; Natelson, Benjamin H; Lange, Gudrun; Vu, Diana; Blate, Michelle; Klimas, Nancy G.; Balbin, Elizabeth G.; Bateman, Lucinda; Allen, Ali; Lapp, Charles W.; Springs, Wendy; Kogelnik, Andreas M.; Phan, Catrina C.; Danver, Joan; Podell, Richard N.; Fitzpatrick, Trisha; Peterson, Daniel L.; Gottschalk, C. Gunnar; Rajeevan, Mangalathu S.; MCAM Study Group (2017), "Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.", American Journal of Epidemiology, 1–10, doi:10.1093/aje/kwx029 
  29. Natelson, Benjamin; Vu, Diana; Coplan, Jeremy D.; Mao, Xiangling; Blate, Michelle; Kang, Guoxin; Soto, Eli (2017), "Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia", Fatigue: Biomedicine, Health & Behavior, doi:10.1080/21641846.2017.1280114 
  30. Natelson, Benjamin; Mao, Xiangling; Stegner, Aaron J; Lange, Gudrun; Vu, Diana; Blate, Michelle; Kang, Guoxin; Soto, Eli; Kapusuz, Tolga; Shungu, Dikoma C (2017), "Multimodal and simultaneous assessments of brain and spinal fluid abnormalities in chronic fatigue syndrome and the effects of psychiatric comorbidity", Journal of the Neurological Sciences, 375: 411-416, doi:10.1016/j.jns.2017.02.046 
  31. Serrador, Jorge M.; Quigley, Karen; Zhao, Caixiab; Findley, Thomas; Natelson, Benjamin H. (2018), "Balance deficits in Chronic Fatigue Syndrome with and without fibromyalgia", NeuroRehabilitation, 42 (2): 235-246, doi:10.3233/NRE-172245 
  32. Natelson, Benjamin H. (Feb 2019). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences". Clinical Therapeutics. doi:10.1016/j.clinthera.2018.12.016. 

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

Cognition - Thought processes, including attention, reasoning, and memory.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.