Gene expression

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Upregulated genes in ME/CFS in one study
Author: Sweetman et al. Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics 2019 9(3) 73. License: CC-BY-4.0

The National Center for Biotechnology Information at the US National Institutes of Health (NIH) defines gene expression as "the phenotypic manifestation of a gene or genes by the processes of genetic transcription and genetic translation."[1] Gene expression takes place in two stages. The first is transcription: the base sequence on DNA is copied to a molecule of mRNA. Next, translation: the mRNA molecule leaves the cell nucleus for the cytoplasm and specifies the particular amino acids that will make up individual proteins in the process of protein synthesis.[1]

Gene expression analysis examines patterns of gene expression in transcription, whether under specific conditions or in certain kinds of cells.[1]

Notable studies[edit | edit source]

  • 2009, A gene signature for post-infectious chronic fatigue syndrome[2]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 "Gene Expression". ncbi.nlm.nih.gov. Retrieved January 31, 2019.
  2. ↑ Gow, John W; Hagan, Suzanne; Herzyk, Pawel; Cannon, Celia; Behan, Peter O; Chaudhuri, Abhijit (June 25, 2009). "A gene signature for post-infectious chronic fatigue syndrome". BMC Medical Genomics. 2: 38. doi:10.1186/1755-8794-2-38. ISSN 1755-8794. PMC 2716361. PMID 19555476.
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