Julia Newton

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Julia L. Newton is a Clinical Professor of Ageing and Medicine at the University of Newcastle in the United Kingdom. She has published a number of ME/CFS studies focusing on autonomic nervous system dysfunction[1] and the role of inflammation in fatigue. She is a member of the UK CFS/ME Collaborative and is the Joint Medical Adviser of the charity Action for ME.

She is Director of the Newcastle Fatigue Research Group [2] and Associate Medical Director for Research for Newcastle upon Tyne Hospitals NHS Foundation Trust.

Notable studies[edit | edit source]

Talks & interviews[edit | edit source]

Talks for Dutch ME/CFS Society

2014, Playlist on YouTube containing:

Invest in ME International ME Conferences

  • 2008, Speaker at the 3rd Invest in ME International ME Conference on Autonomic Dysfunction: Identification of aetiologically distinct subject groups within ME/CFS[52]DVD available
  • 2014, Speaker at the 9th Invest in ME International ME Conference [53]DVD available

Learn more[edit | edit source]

Online presence[edit | edit source]

References[edit | edit source]

  1. "Staff Profile - Institute of Cellular Medicine - Newcastle University". www.ncl.ac.uk. Retrieved Aug 10, 2018. 
  2. "Fatigue Research - Faculty of Medical Sciences - Newcastle University". www.ncl.ac.uk. Retrieved Aug 10, 2018. 
  3. Hoad, A.; Spickett, G.; Elliott, J.; Newton, J. (2008). "Postural orthostatic tachycardia syndrome is an under-recognized condition in chronic fatigue syndrome". QJM: monthly journal of the Association of Physicians. 101 (12): 961–965. doi:10.1093/qjmed/hcn123. ISSN 1460-2393. PMID 18805903. 
  4. Newton, Julia L.; Sheth, Amish; Shin, Jane; Pairman, Jessie; Wilton, Katharine; Burt, Jennifer A.; Jones, David E. J. (Apr 2009). "Lower Ambulatory Blood Pressure in Chronic Fatigue Syndrome". Psychosomatic Medicine. 71 (3): 361–365. doi:10.1097/psy.0b013e31819ccd2a. ISSN 0033-3174. 
  5. Hollingsworth, Kieren G.; Jones, David E. J.; Taylor, Roy; Blamire, Andrew M.; Newton, Julia L. (May 17, 2010). "Impaired cardiovascular response to standing in Chronic Fatigue Syndrome". European Journal of Clinical Investigation. 40 (7): 608–615. doi:10.1111/j.1365-2362.2010.02310.x. ISSN 0014-2972. 
  6. Newton, JL; Mabillard, H; Scott, A; Hoad, A; Spickett, G (Dec 1, 2010). "The Newcastle NHS Chronic Fatigue Syndrome Service: not all fatigue is the same" (PDF). The Journal of the Royal College of Physicians of Edinburgh. 40 (4): 304–307. doi:10.4997/jrcpe.2010.404. ISSN 1478-2715. 
  7. Jones, David E. J.; Hollingsworth, Kieren G.; Jakovljevic, Djordje G.; Fattakhova, Gulnar; Pairman, Jessie; Blamire, Andrew M.; Trenell, Michael I.; Newton, Julia L. (2011), "Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case–control study", European Journal of Clinical Investigation, 42 (2), doi:10.1111/j.1365-2362.2011.02567.x 
  8. Hollingsworth, KG; Hodgson, T; MacGowan, GA; Blamire, AM; Newton, JL (2012), "Impaired cardiac function in chronic fatigue syndrome measured using magnetic resonance cardiac tagging", Journal of Internal Medicine, 271: 264–270, doi:10.1111/j.1365-2796.2011.02429.x 
  9. Frith, J.; Zalewski, P.; Klawe, J. J.; Pairman, J.; Bitner, A.; Tafil-Klawe, M.; Newton, J. L. (Sep 1, 2012). "Impaired blood pressure variability in chronic fatigue syndrome—a potential biomarker". QJM: An International Journal of Medicine. 105 (9): 831–838. doi:10.1093/qjmed/hcs085. ISSN 1460-2725. 
  10. He, Jiabao; Hollingsworth, Kieren G.; Newton, Julia L.; Blamire, Andrew M. (2013), "Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation", NeuroImage: Clinical, 2: 168-173, doi:10.1016/j.nicl.2012.12.006 
  11. Jason, LA; Brown, A; Evans, M; Sunnquist, M; Newton, JL (2013), "Contrasting chronic fatigue syndrome versus myalgic encephalomyelitis/chronic fatigue syndrome", Fatigue: Biomedicine, Health & Behavior, 1 (3): 168-183, doi:10.1080/21641846.2013.774556 
  12. Gotts, Z.M.; Ellis, J. G.; Newton, Julia L.; Deary, V. (2014), "The role of sleep in chronic fatigue syndrome: a narrative review", Fatigue: Biomedicine, Health & Behavior, 2 (3): 163-184, doi:10.1080/21641846.2014.935607 
  13. Robinson, L. J., Durham, J., MacLachlan, L. L., & Newton, J. L. (2015). Autonomic function in chronic fatigue syndrome with and without painful temporomandibular disorder. Fatigue: Biomedicine, Health & Behavior, 3(4), 205-219.
  14. Jason, L.A.; Sunnquist, M.; Brown, A.; Newton, J.L.; Strand, E.B.; Vernon, S.D. (2015), "Chronic fatigue syndrome versus systemic exertion intolerance disease", Fatigue: Biomedicine, Health & Behavior, 3 (3): 127-141, doi:10.1080/21641846.2015.1051291 
  15. Jason, Leonard A; Sunnquist, Madison; Brown, Abigail; Furst, Jacob; Cid, Marjoe; Farietta, Jillianna; Kot, Bobby; Bloomer, Craig; Nicholson, Laura; Williams, Yolonda; Jantke, Rachel; Newton, Julia L; Strand, Elin Bolle (2015), "Factor Analysis of the DePaul Symptom Questionnaire: Identifying Core Domains", Journal of Neurology and Neurobiology, 1 (4), doi:10.16966/2379-7150.114 
  16. Brown, Audrey E.; Jones, David E.; Walker, Mark; Newton, Julia L. (2015), "Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome", PLoS One, 10 (4), doi:10.1371/journal.pone.0122982 
  17. Jason, LA; Kot, B; Sunnquist, M; Brown, A; Reed, J; Furst, J; Newton, JL; Strand, EB; Vernon, SD (2015), "Comparing and Contrasting Consensus versus Empirical Domains", Fatigue: biomedicine, health & behavior, 3 (2): 63-74, doi:10.1080/21641846.2015.1017344, PMID 26977374 
  18. Rutherford, Gina; Manning, Philip; Newton, Julia L. (2016), "Understanding Muscle Dysfunction in Chronic Fatigue Syndrome", Journal of Aging Research, doi:10.1155/2016/2497348 
  19. Gotts, Zoe; Deary, Vincent; Newton, Julia; Ellis, Jason (2016), "Treatment of insomnia reduces fatigue in chronic fatigue syndrome in those able to comply with the intervention", Fatigue: Biomedicine, Health & Behavior, 4 (4): 208-216, doi:10.1080/21641846.2016.1222699 
  20. Pendergrast, Tricia; Brown, Abigail; Sunnquist, Madison; Jantke, Rachel L.; Newton, Julia L.; Strand, Elin Bolle; Jason, Leonard A. (2016), "Housebound versus nonhousebound patients with myalgic encephalomyelitis and chronic fatigue syndrome", Chronic Illness, doi:10.1177/1742395316644770 
  21. Thorpe, Taylor; McManimen, Stephanie; Gleason, Kristen; Stoothoff, Jamie; Newton, Julia L.; Strand, Elin Bolle; Jason, Leonard A. (2016), "Assessing current functioning as a measure of significant reduction in activity level", Fatigue: Biomedicine, Health & Behavior, 4 (3): 175-188, doi:10.1080/21641846.2016.1206176 
  22. Kidd, Elizabeth; Brown, Abigail; McManimen, Stephanie; Jason, Leonard A.; Newton, Julia L.; Strand, Elin B. (2016), "The Relationship between Age and Illness Duration in Chronic Fatigue Syndrome", Diagnostics, 6 (2): 16, doi:10.3390/diagnostics6020016 
  23. Newton, Julia L.; Finkelmeyer, Andreas; Petrides, George; Frith, James; Hodgson, Tim; Maclachlan, Laura; MacGowan, Guy; Blamire, Andrew M. (2016), "Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study", Open Heart, 3 (1), doi:10.1136/openhrt-2015-000381 
  24. Clark, James E.; Ng, W. Fai; Watson, Stuart; Newton, Julia L. (2016), "The aetiopathogenesis of fatigue: unpredictable, complex and persistent", British Medical Bulletin, 2016 (117): 139–148, doi:10.1093/bmb/ldv057 
  25. Gotts, Z.M.; Deary, V.; Newton, Julia L.; Ellis, J. G. (2016), "A comparative polysomnography analysis of sleep in healthy controls and patients with chronic fatigue syndrome.", Fatigue: Biomedicine, Health & Behavior, 4 (2): 80-93, doi:10.1080/21641846.2016.1167470 
  26. Jason, L. A.; McManimen, S.; Sunnquist, Madison; Brown, A.; Furst, J.; Newton, J. L.; Strand, E. B. (2016), "Case definitions integrating empiric and consensus perspectives", Fatigue: Biomedicine, Health & Behavior, 4 (1): 1-23, doi:10.1080/21641846.2015.1124520 
  27. Jason, Leonard A; Sunnquist, Madison; Brown, Abigail; Evans, Meredyth; Newton, Julia L (2016), "Are Myalgic Encephalomyelitis and chronic fatigue syndrome different illnesses? A preliminary analysis", Journal of Health Psychology, 21 (1): 3-15, doi:10.1177/1359105313520335 
  28. Jason, Leonard A; McManimen, Stephanie; Sunnquist, Madison; Newton, Julia L; Strand, Elin Bolle (2017), "Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia", ECronicon, 5 (1): 19-28, PMID 28713879 
  29. Maclachlan, Laura; Watson, Stuart; Gallagher, Peter; Finkelmeyer, Andreas; Jason, Leonard A.; Sunnquist, Madison; Newton, Julia L. (2017), "Are current chronic fatigue syndrome criteria diagnosing different disease phenotypes?", PLOS One, doi:10.1371/journal.pone.0186885 
  30. Tomas, Cara; Finkelmeyer, Andreas; Hodgson, Tim; MacLachlan, Laura; MacGowan, Guy A; Blamire, Andrew M; Newton, Julia L (2017), "Elevated brain natriuretic peptide levels in chronic fatigue syndrome associate with cardiac dysfunction: a case control study", Open Heart, doi:10.1136/openhrt-2017-000697 
  31. Strassheim, Victoria; Lambson, Rebecca; Hackett, Katie L.; Newton, Julia L. (Jul 3, 2017). "What is known about severe and very severe chronic fatigue syndrome? A scoping review". Fatigue: Biomedicine, Health & Behavior. 5 (3): 167–183. doi:10.1080/21641846.2017.1333185. ISSN 2164-1846. 
  32. Jason, LA; McManimen, S; Sunnquist, M; Newton, JL; Strand, EB (2017), "Clinical criteria versus a possible research case definition in chronic fatigue syndrome/myalgic encephalomyelitis", Fatigue: biomedicine, health & behavior, doi:10.1080/21641846.2017.1299077 
  33. Davidson, Sean L.; Gotts, Zoe M.; Ellis, Jason G.; Newton, Julia L. (Mar 2017), "Two year follow-up of sleep diaries and polysomnography in chronic fatigue syndrome: a cohort study", Fatigue: Biomedicine, Health & Behavior, doi:10.1080/21641846.2017.1297280 
  34. O’connor, Kelly; Sunnquist, Madison; Nicholson, Laura; Jason, Leonard A; Newton, Julia L; Strand, Elin B (Dec 12, 2017). "Energy envelope maintenance among patients with myalgic encephalomyelitis and chronic fatigue syndrome: Implications of limited energy reserves". Chronic Illness: 174239531774647. doi:10.1177/1742395317746470. ISSN 1742-3953. PMID 29231037. 
  35. Tomas, Cara; Brown, Audrey; Strassheim, Victoria; Elson, Joanna; Newton, Julia; Manning, Philip (Oct 24, 2017). "Cellular bioenergetics is impaired in patients with chronic fatigue syndrome". PLOS ONE. 12 (10): e0186802. doi:10.1371/journal.pone.0186802. ISSN 1932-6203. PMID 29065167. 
  36. Schoeman, Elizna M.; Van Der Westhuizen, Francois H.; Erasmus, Elardus; van Dyk, Etresia; Knowles, Charlotte V. Y.; Al-Ali, Shereen; Ng, Wan-Fai; Taylor, Robert W.; Newton, Julia L. (Mar 16, 2017). "Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome". BMC Medical Genetics. 18 (1). doi:10.1186/s12881-017-0387-6. ISSN 1471-2350. PMID 28302057. 
  37. Zalewski, Pawel; Finkelmeyer, Andreas; Frith, James; Maclachlan, Laura; Blamire, Andrew; Newton, Julia L. (2018), "Liver volume is lower and associates with resting and dynamic blood pressure variability in chronic fatigue syndrome", Fatigue: Biomedicine, Health & Behavior, doi:10.1080/21641846.2018.1488525 
  38. Tomas, Cara; Newton, Julia L (2018), "Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review", Biochemical Society Transactions, doi:10.1042/BST20170503, PMID 29666214 
  39. Brown, Audrey E; Dibnah, Beth; Fisher, Emily; Newton, Julia L; Walker, Mark (2018), "Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS", Bioscience Reports, doi:10.1042/BSR20180242 
  40. Strassheim, Victoria; Welford, Jenny; Ballantine, Rob; Newton, Julia L. (Dec 2018). "Managing fatigue in postural tachycardia syndrome (PoTS): The Newcastle approach". Autonomic Neuroscience. 215: 56–61. doi:10.1016/j.autneu.2018.02.003. 
  41. Clark, James E.; Davidson, Sean L.; Maclachlan, Laura; Newton, Julia L.; Watson, Stuart (2017), "Rethinking childhood adversity in chronic fatigue syndrome", Fatigue: Biomedicine, Health & Behavior, doi:10.1080/21641846.2018.1384095 
  42. Finkelmeyer, Andreas; He, Jiabao; Maclachlan, Laura; Watson, Stuart; Gallagher, Peter; Newton, Julia L.; Blamire, Andrew M. (2018), "Grey and white matter differences in Chronic Fatigue Syndrome – A voxel-based morphometry study", NeuroImage: Clinical, 17: 24-30, doi:10.1016/j.nicl.2017.09.024, PMID 29021956 
  43. Lynn, Megan; Maclachlan, Laura; Finkelmeyer, Andreas; Clark, James; Locke, James; Todryk, Stephen; Ng, Wan-Fai; Newton, Julia L.; Watson, Stuart (2018). "Reduction of glucocorticoid receptor function in Chronic Fatigue Syndrome". Mediators of Inflammation. doi:10.1155/2018/3972104. 
  44. Strassheim, Victoria Jane; Sunnquist, Madison; Jason, Leonard A.; Newton, Julia L. (Sep 1, 2018). "Defining the prevalence and symptom burden of those with self-reported severe chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a two-phase community pilot study in the North East of England". BMJ Open. 8 (9): e020775. doi:10.1136/bmjopen-2017-020775. ISSN 2044-6055. PMID 30232103. 
  45. Venter, Marianne; Tomas, Cara; Pienaar, Ilse S; Strassheim, Victoria; Erasmus, Elardus; Ng, Wan-Fai; Howell, Neil; Newton, Julia L; van der Westhuizen, Francois H; Elson, Joanna L. "MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants". Scientific Reports. ISSN 2045-2322. 
  46. Robinson, Lucy J.; Gallagher, Peter; Watson, Stuart; Pearce, Ruth; Finkelmeyer, Andreas; Maclachlan, Laura; Newton, Julia L. (Feb 5, 2019). "Impairments in cognitive performance in chronic fatigue syndrome are common, not related to co-morbid depression but do associate with autonomic dysfunction". PLOS ONE. 14 (2): e0210394. doi:10.1371/journal.pone.0210394. ISSN 1932-6203. 
  47. Słomko, Joanna; Newton, Julia L; Kujawski, Sławomir; Tafil-Klawe, Małgorzata; Klawe, Jacek; Staines, Donald; Marshall-Gradisnik, Sonya; Zalewski, Pawel (Mar 2019). "Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study". BMJ Open. 9 (3): e023955. doi:10.1136/bmjopen-2018-023955. ISSN 2044-6055. PMID 30850404. 
  48. Tomas, Cara; Brown, Audrey E.; Newton, Julia L.; Elson, Joanna L. (Mar 1, 2019). "Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types". PeerJ. 7: e6500. doi:10.7717/peerj.6500. ISSN 2167-8359. PMID 30847260. 
  49. Strassheim, Victoria; Deary, Vincent; Webster, Deborah A.; Douglas, Jane; Newton, Julia L.; Hackett, Katie L. (Jul 9, 2019). "Conceptualizing the benefits of a group exercise program developed for those with chronic fatigue: a mixed methods clinical evaluation". Disability and Rehabilitation: 1–11. doi:10.1080/09638288.2019.1636315. ISSN 0963-8288. 
  50. Morten, Karl J.; Newton, Julia L.; Joanna L. Elson; Potter, Michelle; Lodge, Tiffany A.; Tomas, Cara (Aug 7, 2019). "Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test". Scientific Reports. 9 (1): 1–9. doi:10.1038/s41598-019-47966-z. ISSN 2045-2322. 
  51. "Standing up for Fatigue - Professor Julia Newton and Professor Jason Ellis". Retrieved Aug 10, 2018. 
  52. Research, Invest in ME. "Invest in ME Research - IIMEC3". www.investinme.eu. Retrieved Aug 10, 2018. 
  53. Research, Invest in ME. "Invest in ME Research - IIMEC9 International ME Conference 2014". www.investinme.eu. Retrieved Aug 10, 2018. 

Myalgic encephalomyelitis or M.E. has different diagnostic criteria to chronic fatigue syndrome; neurological symptoms are required but fatigue is an optional symptom.<ref name="ICP2011primer">{{Citation

Myalgic encephalomyelitis or chronic fatigue syndrome


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