Skeletal muscle

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Skeletal muscle are muscles that move bones and other structures in response to voluntary messages from the nervous system. They are one of the three classifications of muscle. The other two categories are cardiac muscle and smooth muscle. Each category of muscle has a different appearance and different role.

Skeletal muscle tissue is composed of long cells called muscle fibers that have a striated appearance and respond the voluntary commands. They connect to bones via connective tissue called tendons. Movement occurs when nerve cells stimulate the muscle to contract.[1]

Studies[edit | edit source]

  • 1992, Skeletal muscle metabolism in the chronic fatigue syndrome. In vivo assessment by 31P nuclear magnetic resonance spectroscopy.[2](Abstract)
  • 1995, Unusual pattern of mitochondrial DNA deletions in skeletal muscle of an adult human with chronic fatigue syndrome[3] (No abstract available)
  • 1997, Chronic fatigue syndrome and skeletal muscle mitochondrial function [1]
  • 2013, Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation[4](Full Text)
  • 2015, Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome[5]
  • 2018, Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS[6](Full Text)
  • 2018, Old muscle in young body: an aphorism describing the Chronic Fatigue Syndrome[7](Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. https://www.visiblebody.com/learn/muscular/muscle-types
  2. Wong, R; Lopaschuk, G; Zhu, G; Walker, D; Catellier, D; Burton, D; Teo, K; Collins-Nakai, R; Montague, T (Dec 1992), "Skeletal muscle metabolism in the chronic fatigue syndrome. In vivo assessment by 31P nuclear magnetic resonance spectroscopy", Chest, 102 (6): 1716–22, PMID 1446478 
  3. Zhang, C; Baumer, A; Mackay, IR; Linnane, AW; Nagley, P (Apr 1995), "Unusual pattern of mitochondrial DNA deletions in skeletal muscle of an adult human with chronic fatigue syndrome", Human Molecular Genetics, 4 (4): 751–754, PMID 7633428 
  4. He, Jiabao; Hollingsworth, Kieren G.; Newton, Julia L.; Blamire, Andrew M. (2013), "Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation", NeuroImage: Clinical, 2: 168-173, doi:10.1016/j.nicl.2012.12.006 
  5. Brown, Audrey E.; Jones, David E.; Walker, Mark; Newton, Julia L. (2015), "Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome", PLoS One, 10 (4), doi:10.1371/journal.pone.0122982 
  6. Brown, Audrey E; Dibnah, Beth; Fisher, Emily; Newton, Julia L; Walker, Mark (2018), "Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS", Bioscience Reports, doi:10.1042/BSR20180242 
  7. Pietrangelo, Tiziana; Fulle, Stefania; Coscia, Francesco; Gigliotti, Paola Virginia; Fanò-Illic, Giorgio (Sep 7, 2018). "Old muscle in young body: an aphorism describing the Chronic Fatigue Syndrome". European Journal of Translational Myology. 28 (3). doi:10.4081/ejtm.2018.7688. ISSN 2037-7460. PMID 30344981. 

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

mitochondria - Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.