Muscle spasm: Difference between revisions

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m (Text replacement - "<ref name="CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 =...)
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| isbn = 978-0-9739335-3-6
| isbn = 978-0-9739335-3-6
| url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf
| url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf
}}</ref><ref name="CCC">{{Citation
}}</ref><ref name="CCC">{{Cite journal | last1  = Carruthers    | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2  = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain| last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir| last4  = Peterson      | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5  = Klimas        | first5 = Nancy G. | authorlink5 = Nancy Klimas| last6  = Lerner        | first6 = A. Martin | authorlink6 = Martin Lerner | last7  = Bested        | first7 = Alison C. | authorlink7 = Alison Bested| last8  = Flor-Henry    | first8 = Pierre | authorlink8 = Pierre Flor-Henry | last9  = Joshi        | first9 = Pradip | authorlink9 = Pradip Joshi | last10  = Powles | first10 = A C Peter    | authorlink10 = A C Peter Powles | last11  = Sherkey     | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey| last12  = van de Sande  | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande| title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 |issue = 2 | pages = 7-115| date=2003| pmid = | doi = 10.1300/J092v11n01_02 |url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref><ref name="fukuda1994">{{Cite journal|last=Fukuda|first=K.|author-link=Keiji Fukuda|last2=Straus|first2=S. E.|author-link2=Stephen Straus|last3=Hickie|first3=I.|author-link3=Ian Hickie|last4=Sharpe|first4=M. C.|author-link4=Michael Sharpe|last5=Dobbins|first5=J. G.|author-link5=James Dobbins|last6=Komaroff|first6=A.|author-link6=Anthony Komaroff|date=1994-12-15|title=The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group|url=https://www.researchgate.net/profile/Michael_Sharpe2/publication/247808895_The_Chronic_Fatigue_Syndrome_A_Comprehensive_Approach_to_Its_Definition_and_Study/links/0c96053201643bfc4b000000/The-Chronic-Fatigue-Syndrome-A-Comprehensive-Approach-to-Its-Definition-and-Study.pdf|journal=Annals of Internal Medicine|volume=121|issue=12|pages=953–959|issn=0003-4819|pmid=7978722|via=|publisher=American College of Physicians}}</ref>
| last1  = Carruthers    | first1 = Bruce M.     | authorlink1 = Bruce Carruthers  
| last2  = Jain         | first2 = Anil Kumar   | authorlink2 = Anil Kumar Jain
| last3   = De Meirleir   | first3 = Kenny L.     | authorlink3 = Kenny De Meirleir
| last4  = Peterson      | first4 = Daniel L.     | authorlink4 = Daniel Peterson
| last5  = Klimas        | first5 = Nancy G.     | authorlink5 = Nancy Klimas
| last6  = Lerner        | first6 = A. Martin     | authorlink6 = Martin Lerner
| last7  = Bested        | first7 = Alison C.     | authorlink7 = Alison Bested
| last8  = Flor-Henry    | first8 = Pierre       | authorlink8 = Pierre Flor-Henry  
| last9  = Joshi        | first9 = Pradip       | authorlink9 = Pradip Joshi
| last10  = Powles       | first10 = A C Peter    | authorlink10 = A C Peter Powles
| last11  = Sherkey       | first11 = Jeffrey A.   | authorlink11 = Jeffrey Sherkey
| last12  = van de Sande  | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande
| title   = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols
| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | page = 7-115
| date   = 2003
| pmid   =  
| doi     = 10.1300/J092v11n01_02
| url     = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf
}}</ref><ref name="fukuda1994">{{Cite journal|last=Fukuda|first=K.|author-link=Keiji Fukuda|last2=Straus|first2=S. E.|author-link2=Stephen Straus|last3=Hickie|first3=I.|author-link3=Ian Hickie|last4=Sharpe|first4=M. C.|author-link4=Michael Sharpe|last5=Dobbins|first5=J. G.|author-link5=James Dobbins|last6=Komaroff|first6=A.|author-link6=Anthony Komaroff|date=1994-12-15|title=The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group|url=https://www.researchgate.net/profile/Michael_Sharpe2/publication/247808895_The_Chronic_Fatigue_Syndrome_A_Comprehensive_Approach_to_Its_Definition_and_Study/links/0c96053201643bfc4b000000/The-Chronic-Fatigue-Syndrome-A-Comprehensive-Approach-to-Its-Definition-and-Study.pdf|journal=Annals of Internal Medicine|volume=121|issue=12|pages=953–959|issn=0003-4819|pmid=7978722|via=|publisher=American College of Physicians}}</ref>


Muscle spasm is a potential symptom of [[Long COVID]] in the [[World Health Organization Long COVID diagnostic criteria|World Health Organization]]'s definition.<ref name="WHO-longcovid-criteria">{{citation|title =A clinical case definition of post COVID-19 condition by a Delphi consensus
Muscle spasm is a potential symptom of [[Long COVID]] in the [[World Health Organization Long COVID diagnostic criteria|World Health Organization]]'s definition.<ref name="WHO-longcovid-criteria">{{citation|title =A clinical case definition of post COVID-19 condition by a Delphi consensus

Revision as of 02:35, May 11, 2022

Muscle spasms or cramp, also known as involuntary hypertonicity, are unintentional and painful muscle contractions.[1] The pain from spasms is very sharp and intense, for example waking someone suddenly in the night, and the muscle may sometimes look hard under the skin.[2] Spasms can make it impossible to use the muscle temporarily.[2]

Prevalence[edit | edit source]

Symptom recognition[edit | edit source]

Muscle spasms are not considered a diagnostic criteria for ME/CFS, but have been found to occur in people with ME/CFS.[3][4][5]

Muscle spasm is a potential symptom of Long COVID in the World Health Organization's definition.[6]

Notable studies[edit | edit source]

Possible causes[edit | edit source]

Muscle spasms can occur as a result of many different illnesses including:

Spasms can also be caused by

  • injury
  • dehydration
  • prolonged exercise, especially in hot weather
  • low levels of potassium, magnesium or calcium, which can result from using diuretics
  • pregnancy
  • nerve compression, particularly in the spine.[1][2]

Treatments[edit | edit source]

Drugs that treat spams are known as muscle relaxants or antispasmodics.[1]

The Canadian Consensus Criteria suggests treating muscle spasms in ME/CFS with:

  • Heat, both general and local heat
  • Baclofen (used off-label)[4]

The International Consensus Criteria primer for clinicians suggests using magnesium sulphate.[3]

Muscle spasms can also be treated with skeletal and muscle relaxants such as carisoprodol, metaxalone, methocarbamol, tizanidine, orphenadrine and cyclobenzapine.[1]

Alternative drugs for muscle spasms include diazepam (Valium), and medical marijuana (cannabis), although this has less scientific evidence.[1]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 1.4 1.5 "Muscle spasm (Involuntary Hypertonicity)". drugs.com. Retrieved February 20, 2021.
  2. 2.0 2.1 2.2 2.3 2.4 "Muscle cramp". drugs.com. Retrieved February 20, 2021.
  3. 3.0 3.1 Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
  4. 4.0 4.1 4.2 4.3 Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF). Journal of Chronic Fatigue Syndrome. 11 (2): 7–115. doi:10.1300/J092v11n01_02.
  5. Fukuda, K.; Straus, S. E.; Hickie, I.; Sharpe, M. C.; Dobbins, J. G.; Komaroff, A. (December 15, 1994). "The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group" (PDF). Annals of Internal Medicine. American College of Physicians. 121 (12): 953–959. ISSN 0003-4819. PMID 7978722.
  6. Soriano, Joan B.; Allan, Maya; Alsokhn, Carine; Alwan, Nisreen A.; Askie, Lisa; Davis, Hannah E.; Diaz, Janet V.; Dua, Tarun; de Groote, Wouter; Jakob, Robert; Lado, Marta; Marshall, John; Murthy, Srin; Preller, Jacobus; Relan, Pryanka; Schiess, Nicoline; Seahwag, Archana (October 6, 2021), A clinical case definition of post COVID-19 condition by a Delphi consensus, World Health Organization (WHO) clinical case definition working group on post COVID-19 condition, World Health Organization