Christopher Snell

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Jump to: navigation, search
Source:Workwell

Christopher Ronald Snell, PhD, is the Scientific Director of Workwell Foundation, Ripon, California. He directs the Pacific Fatigue Lab at the Department of Health, Exercise, and Sport Sciences, at the University of the Pacific, Stockton, California, US.[1]

IOM Committee on Diagnostic Criteria for ME/CFS[edit | edit source]

Dr Snell was a reviewer for the 2015 report produced by the Institute of Medicine's (IOM) Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).[2]

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

Dr. Snell was Chair of the Health and Human Services's (HHS) Chronic Fatigue Syndrome Advisory Committee (CFSAC) committee from 04/01/07-04/01/11.[3]

Open letter to The Lancet[edit | edit source]

Three open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Snell, along with 42 colleagues in the ME/CFS field, signed the second letter.[4] In 2018, Dr. Snell, with more than 100 colleagues in the ME/CFS field, signed the third letter.[5]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Member of the Quality of Life/Functional Status (CPET)/Activity Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke (NINDS) and the Centers for Disease Control and Prevention (CDC).[6]

Notable studies[edit | edit source]

  • 2001, Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome[7]ABSTRACT
  • 2001, Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective[8]ABSTRACT
  • 2002, Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome[9]ABSTRACT
  • 2003, Subclassifying chronic fatigue syndrome through exercise testing[10]ABSTRACT
  • 2004, Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health[11]ABSTRACT
  • 2005, Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)[12]FULL TEXT
  • 2007, Legal and Scientific Considerations of the Exercise Stress Test[13]ABSTRACT
  • 2007, Diminished Cardiopulmonary Capacity During Post-Exertional Malaise[14]ABSTRACT
  • 2010, Post-exertional malaise in women with chronic fatigue syndrome[15]ABSTRACT
  • 2010, Conceptual model for physical therapist management of chronic fatigue syndrome/myalgic encephalomyelitis[16]ABSTRACTFULL TEXT
  • 2011, Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue[17]ABSTRACT
  • 2011, Diagnostic accuracy of symptoms characterising chronic fatigue syndrome[18]ABSTRACT
  • 2012, Minimum data elements for research reports on CFS[19]FULL TEXT
  • 2013, Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome[20]FULL TEXT
  • 2018, Editorial - Checking our blind spots: current status of research evidence summaries in ME/CFS.[21](Introduction)
  • 2018, Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[22]Abstract
  • 2019, Chronotropic Intolerance: An Overlooked Determinant of Symptoms and Activity Limitation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?[23](Full text)
  • 2019, Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing[24](Full text)

Talks and interviews[edit | edit source]

  • 2011, National Institutes of Health (NIH) State of the Knowledge Workshop regarding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Research presenter
Cardiopulmulmonary Exercise Testing to Assess fatigue in ME/CFS (presentation starts at the 8:02:00 time marker)[25]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. https://www.researchgate.net/profile/Christopher_Snell-UOP
  2. https://www.nap.edu/resource/19012/MECFS_Powerpoint.pdf
  3. http://nih.granicus.com/DocumentViewer.php?file=nih_e174f9bd-ae0f-4a45-9955-827cb608db2f.pdf
  4. "Open Letter Lancet Again". 
  5. "An Open Letter to The Lancet, Two Years On". 
  6. "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved Oct 11, 2019. 
  7. VanNess, J Mark; Snell, Christopher R; Fredrickson, Dean M.; Strayer, David R.; Stevens, Staci R (2001), "Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome", Journal of Chronic Fatigue Syndrome, 8 (3-4): 103-109, doi:10.1300/J092v08n03_09 
  8. Snell, Christopher R; Stevens, Staci R; VanNess, J Mark (2001), "Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective", Journal of Chronic Fatigue Syndrome, 8 (3-4): 117-121, doi:10.1300/J092v08n03_11 
  9. Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2002), "Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome", In Vivo, 16 (2): 107-9, PMID 12073768 
  10. VanNess, J Mark; Snell, Christopher R; Strayer, David R.; Dempsey, IV, Line; Stevens, Staci R (2003), "Subclassifying chronic fatigue syndrome through exercise testing", Med Sci Sports Exerc, 35 (6): 908-13, doi:10.1249/01.MSS.0000069510.58763.E8, PMID 12783037 
  11. Gerrity, T.R.; Papanicolaou, D.A.; Amsterdam, J.D.; Bingham, S.; Grossman, A.; Hedrick, T.; Herberman, R.B.; Krueger, G.; Levine, S.; Mohagheghpour, N.; Moore, R.C.; Oleske, J.M.; Snell, C.R.; CFIDS Association of America (2004), "Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health", Neuroimmunomodulation, 11: 351–357, doi:10.1159/000080144, PMID 15467349 
  12. Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2005), "Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)", In Vivo, 19 (2): 387-90, PMID 15796202 
  13. Ciccolella, Margaret; Stevens, Staci R.; Snell, Christopher R.; Vanness, J. Mark (2007), "Legal and Scientific Considerations of the Exercise Stress Test", Journal of Chronic Fatigue Syndrome, 14 (2): 61-75, doi:10.1300/J092v14n02_06 
  14. VanNess, J Mark; Snell, Christopher R; Stevens, Staci R (2007), "Diminished Cardiopulmonary Capacity During Post-Exertional Malaise", Journal of Chronic Fatigue Syndrome, 14 (2): 77-85, doi:10.1300/J092v14n02_07 
  15. VanNess, J Mark; Stevens, Staci R; Bateman, Lucinda; Stiles, Travis L; Snell, Christopher R (Jan 4, 2010), "Post-exertional malaise in women with chronic fatigue syndrome", J Womens Health (Larchmt), 2010 Feb;19 (2): 239-44, doi:10.1089/jwh.2009.1507, PMID 20095909 
  16. Davenport, Todd E.; Stevens, Staci R.; Snell, Christopher R.; Little, Tamara (2010), "Conceptual Model for Physical Therapist Management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", Physical Therapy, 90 (4): 602–614, doi:10.2522/ptj.20090047, PMID 20185614 
  17. Davenport, Todd E.; Stevens, Staci R.; Baroni, K; Vanness, J. Mark; Snell, Christopher R. (2011), "Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue", Disabil Rehabil, 33 (25-26): 2596-604, doi:10.3109/09638288.2011.582925, PMID 21682669 
  18. Davenport, Todd E.; Stevens, Staci R.; Baroni, Katie; Vanness, J. Mark; Snell, Christopher R. (2011), "Diagnostic accuracy of symptoms characterizing chronic fatigue syndrome", Disabil Rehabil, 33 (19-20): 1768-75, doi:10.3109/09638288.2010.546936, PMID 21208154 
  19. Jason, LA; Unger, ER; Dimitrakoff, JD; Fagin, AP; Houghton, M; Cook, DB; Marshall, GD, Jr; Klimas, N; Snell, C (2012), "Minimum data elements for research reports on CFS", Brain, Behavior, Immunology, 26 (3): 401-6, doi:10.1016/j.bbi.2012.01.014, PMID 22306456 
  20. Snell, Christopher R; Stevens, Staci R; Davenport, Todd E.; VanNess, J Mark (2013), "Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome", Physical Therapy, 93 (11): 1484–1492, doi:10.2522/ptj.20110368 
  21. Davenport, Todd E.; Stevens, Staci R.; VanNess, J. Mark; Stevens, Jared; Snell, Christopher R. (Jul 17, 2018). "Checking our blind spots: current status of research evidence summaries in ME/CFS". Br J Sports Med: bjsports–2018–099553. doi:10.1136/bjsports-2018-099553. ISSN 0306-3674. PMID 30018122. 
  22. Stevens, Staci; Snell, Chris; Stevens, Jared; Keller, Betsy; VanNess, J. Mark (2018). "Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Pediatrics. 6. doi:10.3389/fped.2018.00242. ISSN 2296-2360. 
  23. Davenport, Todd E.; Lehnen, Mary; Stevens, Staci R.; VanNess, J. Mark; Stevens, Jared; Snell, Christopher R. (Mar 22, 2019). "Chronotropic Intolerance: An Overlooked Determinant of Symptoms and Activity Limitation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?". Frontiers in Pediatrics. 7. doi:10.3389/fped.2019.00082. ISSN 2296-2360. 
  24. Bouquet, Jerome; Li, Tony; Gardy, Jennifer L.; Kang, Xiaoying; Stevens, Staci; Stevens, Jared; VanNess, Mark; Snell, Christopher; Potts, James; Miller, Ruth R.; Morshed, Muhammad; McCabe, Mark; Parker, Shoshana; Uyaguari, Miguel; Tang, Patrick; Steiner, Theodore; Chan, Wee-Shian; De Souza, Astrid-Marie; Mattman, Andre; Patrick, David M.; Chiu, Charles Y. (Mar 21, 2019). "Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing". PLOS ONE. 14 (3): e0212193. doi:10.1371/journal.pone.0212193. ISSN 1932-6203. PMID 30897114. 
  25. http://www.pacific.edu/Academics/Schools-and-Colleges/College-of-the-Pacific/Academics/Departments-and-Programs/Archives.html

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

Chronic fatigue syndrome advisory committee (CFSAC) - (sometimes pronounced SIF-SACK) A US government advisory council that met twice per year, covering current topics related to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Meetings usually lasted for two days and the results were presented to the Secretary of Health and Human Services (HHS). After 15 years, on September 5, 2018, CFSAC's charter was not renewed by the Department of HHS, effectively dissolving the committee without notice or warning.

Chronic fatigue syndrome advisory committee (CFSAC) - (sometimes pronounced SIF-SACK) A US government advisory council that met twice per year, covering current topics related to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Meetings usually lasted for two days and the results were presented to the Secretary of Health and Human Services (HHS). After 15 years, on September 5, 2018, CFSAC's charter was not renewed by the Department of HHS, effectively dissolving the committee without notice or warning.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

Accuracy - The "closeness of an observation to the true clinical state". With respect to diagnostic tests, "accuracy" means how specific and sensitive the test is.

Virome - The human virome is the collection of all viruses that are found in or on humans

Post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.