Mark VanNess

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Dr J. Mark VanNess, PhD, is a member of the scientific advisory committee of the Workwell Foundation which specializes in two-day cardiopulmonary exercise testing (2-day CPET) for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fibromyalgia and other fatiguing conditions. He has been working on ME/CFS since 1999, and is particularly interested in issues of autonomic dysfunction and mechanisms that produce post-exertional malaise.

Dr VanNess serves as department chair and Full Professor of Health, Exercise & Sport Sciences, Department of Sport Sciences, and an Adjunct Instructor at the College of Engineering, both at the University of the Pacific, Stockton, California.[1]

Education[edit | edit source]

  • 1990 - BS, Wheaton College, Illinois - Major: Exercise Physiology Minor: Biology[2]
  • 1993 - MS, California State University Sacramento - Thesis Title: "Lactate and Metabolic Responses to Controlled Frequency Breathing During Graded Tethered Swimming"[2]
  • 1997 - PhD, Florida State University - Dissertation Title: "Role of the Paraventricular Hypothalamic Nuclei and Neuropeptide Y in the Antihypertensive Effect of Food Restriction in Aortic Coarctation Hypertension"[2]
  • 1997-1999 - Post-Doctoral Training, Depts. of Pharmacology and Physiology, Univ. Texas Health Science Center. Gender differences in sodium-dependent hypertension[2]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Member of the Quality of Life/Functional Status (CPET)/Activity Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[3]

Notable studies[edit | edit source]

  • 2020, Cardiopulmonary responses to exercise in an individual with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome during long-term treatment with intravenous saline: A case study[4] - (Full text)
  • 2020, Properties of measurements obtained during cardiopulmonary exercise testing in individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[5] - (Full text)
  • 2020, Post-exertional symptoms distinguish Myalgic Encephalomyelitis/Chronic Fatigue Syndrome subjects from healthy controls[6] - (Full text)
  • 2019, Reproducibility of Measurements Obtained During Cardiopulmonary Exercise Testing in Individuals With Fatiguing Health Conditions: A Case Series[7] - (Abstract)
  • 2019, Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing[8] - (Full text)
  • 2019, Chronotropic Intolerance: An Overlooked Determinant of Symptoms and Activity Limitation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?[9] - (Full text)
  • 2018, Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[10] - (Abstract)
  • 2018, Editorial - Checking our blind spots: current status of research evidence summaries in ME/CFS[11] - (Introduction)
  • 2013, Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome[12] - (Full text)
  • 2013, Post-exertion malaise in chronic fatigue syndrome: symptoms and gene expression[13] - (Full text)
  • 2011, Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue[14] - (Full text)
  • 2011, Diagnostic accuracy of symptoms characterising chronic fatigue syndrome[15] - (Abstract)
  • 2011, Psychomotor Function and Response Inhibition in Chronic Fatigue Syndrome[16] - (Full text)
  • 2010, Post-exertional malaise in women with chronic fatigue syndrome[17] - (Abstract)
  • 2007, Diminished Cardiopulmonary Capacity During Post-Exertional Malaise[18] - (Full text)
  • 2007, Legal and Scientific Considerations of the Exercise Stress Test[19] - (Abstract)
  • 2005, Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)[20] - (Full text)
  • 2003, Subclassifying chronic fatigue syndrome through exercise testing[21] - (Abstract)
  • 2002, Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome[22] - (Abstract)
  • 2001, Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective[23] - (Abstract)
  • 2001, Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome[24] - (Abstract)

Other publications[edit | edit source]

Clinic location[edit | edit source]

The Workwell Foundation is based in Ripon, California.

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ http://www.pacific.edu/Academics/Schools-and-Colleges/College-of-the-Pacific/Academics/Departments-and-Programs/Health-Exercise-and-Sport-Sciences/Our-Faculty/Mark-VanNess.html
  2. ↑ 2.0 2.1 2.2 2.3 J. Mark VanNess (July 2015), Curriculum Vitae (PDF) (curriculum vitae)
  3. ↑ "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
  4. ↑ Davenport, Todd E.; Ward, Michael K.; Stevens, Staci R.; Stevens, Jared; Snell, Christopher R.; VanNess, J. Mark (July 20, 2020). "Cardiopulmonary responses to exercise in an individual with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome during long-term treatment with intravenous saline: A case study". Work. 66 (2): 353–359. doi:10.3233/WOR-203214. PMID 32623426.
  5. ↑ Davenport, Todd E.; Stevens, Staci R.; Stevens, Jared; Snell, Christopher R.; Van Ness, J. Mark (July 20, 2020). "Properties of measurements obtained during cardiopulmonary exercise testing in individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Work. 66 (2): 247–256. doi:10.3233/WOR-203170. PMID 32568145.
  6. ↑ Mateo, Lariel J.; Chu, Lily; Stevens, Staci; Stevens, Jared; Snell, Christopher R.; Davenport, Todd; VanNess, J. Mark; Mark VanNess (July 20, 2020). "Post-exertional symptoms distinguish Myalgic Encephalomyelitis/Chronic Fatigue Syndrome subjects from healthy controls". Work. 66 (2): 265–275. doi:10.3233/WOR-203168. PMID 32568143.
  7. ↑ Larson, Benjamin; Davenport, Todd E.; Stevens, Staci R.; Stevens, Jared; Van Ness, J. Mark; Snell, Christopher R. (October 2019). "Reproducibility of Measurements Obtained During Cardiopulmonary Exercise Testing in Individuals With Fatiguing Health Conditions: A Case Series". Cardiopulmonary Physical Therapy Journal. 30 (4): 145–152. doi:10.1097/CPT.0000000000000100. ISSN 1541-7891.
  8. ↑ Bouquet, Jerome; Li, Tony; Gardy, Jennifer L.; Kang, Xiaoying; Stevens, Staci; Stevens, Jared; VanNess, Mark; Snell, Christopher; Potts, James; Miller, Ruth R.; Morshed, Muhammad; McCabe, Mark; Parker, Shoshana; Uyaguari, Miguel; Tang, Patrick; Steiner, Theodore; Chan, Wee-Shian; De Souza, Astrid-Marie; Mattman, Andre; Patrick, David M.; Chiu, Charles Y. (March 21, 2019). "Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing". PLOS ONE. 14 (3): e0212193. doi:10.1371/journal.pone.0212193. ISSN 1932-6203. PMID 30897114.
  9. ↑ Davenport, Todd E.; Lehnen, Mary; Stevens, Staci R.; VanNess, J. Mark; Stevens, Jared; Snell, Christopher R. (March 22, 2019). "Chronotropic Intolerance: An Overlooked Determinant of Symptoms and Activity Limitation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?". Frontiers in Pediatrics. 7. doi:10.3389/fped.2019.00082. ISSN 2296-2360.
  10. ↑ Stevens, Staci; Snell, Chris; Stevens, Jared; Keller, Betsy; VanNess, J. Mark (2018). "Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Pediatrics. 6. doi:10.3389/fped.2018.00242. ISSN 2296-2360.
  11. ↑ Davenport, Todd E.; Stevens, Staci R.; VanNess, J. Mark; Stevens, Jared; Snell, Christopher R. (July 17, 2018). "Checking our blind spots: current status of research evidence summaries in ME/CFS". Br J Sports Med: bjsports–2018–099553. doi:10.1136/bjsports-2018-099553. ISSN 0306-3674. PMID 30018122.
  12. ↑ Snell, Christopher R; Stevens, Staci R; Davenport, Todd E.; VanNess, J Mark (2013). "Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome". Physical Therapy. 93 (11): 1484–1492. doi:10.2522/ptj.20110368.
  13. ↑ Meyer, Jacob D.; Light, Alan R.; Shukla, Sanjay K.; Clevidence, Derek; Yale, Steven; Stegner, Aaron J.; Cook, Dane B. (October 2013). "Post-exertion malaise in chronic fatigue syndrome: symptoms and gene expression". Fatigue: Biomedicine, Health & Behavior. 1 (4): 190–209. doi:10.1080/21641846.2013.838444. ISSN 2164-1846.
  14. ↑ Davenport, Todd E.; Stevens, Staci R.; Baroni, K; Vanness, J. Mark; Snell, Christopher R. (2011), "Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue", Disabil Rehabil, 33 (25–26): 2596–2604, doi:10.3109/09638288.2011.582925, PMID 21682669
  15. ↑ Davenport, Todd E.; Stevens, Staci R.; Baroni, K; Vanness, J. Mark; Snell, Christopher R. (2011), "Diagnostic accuracy of symptoms characterizing chronic fatigue syndrome", Disabil Rehabil, 33 (19–20): 1768–75, doi:10.3109/09638288.2010.546936, PMID 21208154
  16. ↑ https://www.sciencedirect.com/science/article/abs/pii/S0165178110004543
  17. ↑ VanNess, J Mark; Stevens, Staci R; Bateman, Lucinda; Stiles, Travis L; Snell, Christopher R (January 4, 2010). "Post-exertional malaise in women with chronic fatigue syndrome". J Womens Health (Larchmt). 19 (2): 239–244. doi:10.1089/jwh.2009.1507. PMID 20095909.
  18. ↑ VanNess, J Mark; Snell, Christopher R; Stevens, Staci R (2007). "Diminished Cardiopulmonary Capacity During Post-Exertional Malaise". Journal of Chronic Fatigue Syndrome. 14 (2): 77–85. doi:10.1300/J092v14n02_07.
  19. ↑ Ciccolella, Margaret; Stevens, Staci R.; Snell, Christopher R.; Vanness, J. Mark (2007), "Legal and Scientific Considerations of the Exercise Stress Test", Journal of Chronic Fatigue Syndrome, 14 (2): 61–75, doi:10.1300/J092v14n02_06
  20. ↑ Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2005), "Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS)", In Vivo, 19 (2): 387–90, PMID 15796202
  21. ↑ VanNess, J Mark; Snell, Christopher R; Strayer, David R.; Dempsey, IV, Line; Stevens, Staci R (2003), "Subclassifying chronic fatigue syndrome through exercise testing", Med Sci Sports Exerc, 35 (6): 908–913, doi:10.1249/01.MSS.0000069510.58763.E8, PMID 12783037
  22. ↑ Snell, Christopher R; VanNess, J Mark; Strayer, David R.; Stevens, Staci R (2002), "Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome", In Vivo, 16 (2): 107–9, PMID 12073768
  23. ↑ Snell, Christopher R; Stevens, Staci R; VanNess, J Mark (2001), "Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective", Journal of Chronic Fatigue Syndrome, 8 (3–4): 117–121, doi:10.1300/J092v08n03_11
  24. ↑ VanNess, J Mark; Snell, Christopher R; Fredrickson, Dean M.; Strayer, David R.; Stevens, Staci R (2001). "Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 8 (3–4): 103–109. doi:10.1300/J092v08n03_09.
  25. ↑ Snell, C. R., Van Ness, J. M., & Stevens, S. R. (2004). When Working Out Doesn’t Work Out. CFIDS Chronicle, 17(3), 6–9. https://scholarlycommons.pacific.edu/cop-facarticles/456
  26. ↑ Van Ness, J. M. (2014). An Exercise in Objectivity: A realistic approach to exercise in ME/CFS. Paper presented at Watershed Conference in Bristol, England
  27. ↑ "Meeting at Stormont Parliament". ME Research UK. February 12, 2014.
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