Talk:Differential diagnosis

== Would a table organized by category of illness be more readable / more usable? ~Njt (talk) 00:08, January 10, 2022 (UTC) ==

Common comorbidities

Possibly add in a table or add to column below?

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Category Potential comorbidities Autonomic dysfunction postural orthostatic tachycardia syndrome (POTS), neurally mediated hypotension (NMH), orthostatic hypotension Rheumatological disorders Fibromyalgia, Ehlers-Danlos syndrome, temporomandibular joint disorder, Sicca syndrome (dry eyes/mouth) Neurological disorders sensory hypersensitivities - light sensitivity, hyperacusis, touch sensitivity, odor sensitivities or chemical sensitivities), poor balance, migraine, headache, peripheral neuropathy, small fiber neuropathy Immunological disorders new allergies and intolerances or worsened allergies, mast cell activation syndrome, multiple chemical sensitivity, chronic infections and immunodeficiencies Gastrointestinal disorders food allergy, food intolerance, milk protein allergy / intolerance, gut motility issues, celiac disease, irritable bowel syndrome, small intestinal bacterial overgrowth Endocrine/metabolic disorders hypothyroidism, hypothalamus-pituitary-adrenal axis dysregulation (capitals? or hypothalamic-pituitary-adrenal axis dysregulation?) (low normal or flattened cortisol curve), metabolic syndrome Sleep disorders sleep apnea, restless leg syndrome, periodic limb movement disorder Psychiatric disorders secondary anxiety, secondary depression Gynecological disorders endometriosis, Premenstrual syndrome (PMS), vulvodynia MISC interstitial cystitis, overactive bladder, nutritional deficiencies (malnutrition), Vitamin B12 deficiency, Vitamin D deficiency, obesity

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Unable to find references for these statements:

There are however some diseases, which can mimic ME/CFS. Some presentations of these illnesses could meet even the most strict ME/CFS diagnostic criteria (CCC and ICC), resulting in patients being wrongly diagnosed with ME/CFS, whilst suffering from something else. These will be discussed in detail below.

No References but surely other diagnoses are more commonly misdiagnosed then structural issues? ~Njt (talk) 22:23, April 20, 2022 (UTC)

Chiari Malformation

Chiari malformation, is a structural deformity, where a part of the brain stem is out of its normal position. This disease can present with many neurologic symptoms that very similar to ME/CFS and should be excluded. Usually this is done via MRI scan. There was one report however of a missed Chiari problem, that was only visible in a MRI scan in the standing position.

Craniocervical Instability

Craniocervical instability is another structural problem, where the tendons that connect the base of the skull with the spinal cord are loose, causing brain stem compression, which in turn causes many neurologic symptoms similar to ME/CFS. Several anecdotal reports of complete recovery following CCI surgery have been posted on ME/CFS support forums. However it is yet to be determined how common this issue is with ME/CFS patients.

See postural orthostatic tachycardia syndrome.

postural orthostatic tachycardia syndrome (POTS) - A form of orthostatic intolerance where the cardinal symptom is excessive tachycardia due to changing position (e.g. from lying down to sitting up).

See myalgic encephalomyelitis.

See chronic fatigue syndrome.

See Canadian consensus criteria.

Canadian Consensus Criteria (CCC) - A set of diagnostic criteria used to diagnose ME/CFS, developed by a group of practicing ME/CFS clinicians in 2003. The CCC is often considered to be the most complex criteria, but possibly the most accurate, with the lowest number of patients meeting the criteria. Led to the development of the International Consensus Criteria (ICC) in 2011.

International Consensus Criteria (ICC) - A set of diagnostic criteria, based on the Canadian Consensus Criteria, that argued for the abandonment of the term "chronic fatigue syndrome" and encouraged the sole use of the term "myalgic encephalomyelitis".

See International Consensus Criteria.

brainstem Region of the midbrain in adults, includes midbrain, pons, and medulla oblongata and develops.

tendon a fibrous cord of tissue that connects muscle to bone.