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Metabolic syndrome

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Metabolic syndrome or dysmetabolic syndrome or insulin resistance syndrome or Syndrome X is an endocrine disorder that affects approximately 1 in 4 people worldwide, although rates vary considerably between countries.[1][2][3]

Signs and symptoms[edit | edit source]

Metabolic syndrome requires a minimum of 3 of 5 metabolic risk factor criteria to be met:

  • a large waistline (abdominal obesity)
  • a high triglyceride level, or you need medication to control your triglycerides
  • Low HDL cholesterol level, or you need medication to treat low HDL cholesterol
  • High blood pressure, or you need medication to lower your blood pressure
  • High fasting blood sugar, or blood sugar controlled by medication[2]

These often occur together, and are commonly caused by:

Treatment[edit | edit source]

ME/CFS[edit | edit source]

Very little research has been done about metabolic syndrome in people with ME/CFS;[4] the US Clinician Coalition states that it is a possible comorbidity but the International Consensus Criteria and Canadian Consensus Criteria do not.[5][6]

Notable articles[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "ICD-11 for Mortality and Morbidity Statistics". World Health Organization. Retrieved January 12, 2022.
  2. Jump up to: 2.0 2.1 2.2 "Metabolic syndrome". National Heart, Lung and Blood Institute. Retrieved January 12, 2022.
  3. Macías, Nayeli (2021). "Screen-Based Sedentary Behaviors and Their Association With Metabolic Syndrome Components Among Adults in Mexico". Preventing Chronic Disease. 18. doi:10.5888/pcd18.210041. ISSN 1545-1151.
  4. Jump up to: 4.0 4.1 Maloney, Elizabeth M.; Boneva, Roumiana S.; Lin, Jin-Mann S.; Reeves, William C. (September 1, 2010). "Chronic fatigue syndrome is associated with metabolic syndrome: results from a case-control study in Georgia". Metabolism - Clinical and Experimental. 59 (9): 1351–1357. doi:10.1016/j.metabol.2009.12.019. ISSN 0026-0495. PMID 20102774.
  5. Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
  6. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02