Metabolic syndrome

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Metabolic syndrome or dysmetabolic syndrome or insulin resistance syndrome or Syndrome X is an endocrine disorder that affects approximately 1 in 4 people worldwide, although rates vary considerably between countries.[1][2][3]

Signs and symptoms[edit | edit source]

Metabolic syndrome requires a minimum of 3 of 5 metabolic risk factor criteria to be met:

  • a large waistline (abdominal obesity)
  • a high triglyceride level, or you need medication to control your triglycerides
  • Low HDL cholesterol level, or you need medication to treat low HDL cholesterol
  • High blood pressure, or you need medication to lower your blood pressure
  • High fasting blood sugar, or blood sugar controlled by medication[2]

These often occur together, and are commonly caused by:

Treatment[edit | edit source]

ME/CFS[edit | edit source]

Very little research has been done about metabolic syndrome in people with ME/CFS;[4] the US Clinician Coalition states that it is a possible comorbidity but the International Consensus Criteria and Canadian Consensus Criteria do not.[5][6]

Notable articles[edit | edit source]

  • 2009, Chronic fatigue syndrome is associated with metabolic syndrome: results from a case-control study in Georgia[4] (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. "ICD-11 for Mortality and Morbidity Statistics". World Health Organization. Retrieved January 12, 2022.
  2. 2.0 2.1 2.2 "Metabolic syndrome". National Heart, Lung and Blood Institute. Retrieved January 12, 2022.
  3. Macías, Nayeli (2021). "Screen-Based Sedentary Behaviors and Their Association With Metabolic Syndrome Components Among Adults in Mexico". Preventing Chronic Disease. 18. doi:10.5888/pcd18.210041. ISSN 1545-1151.
  4. 4.0 4.1 Maloney, Elizabeth M.; Boneva, Roumiana S.; Lin, Jin-Mann S.; Reeves, William C. (September 1, 2010). "Chronic fatigue syndrome is associated with metabolic syndrome: results from a case-control study in Georgia". Metabolism - Clinical and Experimental. 59 (9): 1351–1357. doi:10.1016/j.metabol.2009.12.019. ISSN 0026-0495. PMID 20102774.
  5. Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
  6. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02