Interstitial cystitis or IC is a bladder condition that usually consists of multiple symptoms such as recurring pelvic pain, pressure, or discomfort in the bladder and pelvic region, and an urgent and frequent need to urinate.
Other names for interstitial cystitis include: painful bladder syndrome (PBS), bladder pain syndrome (BPS), and chronic pelvic pain.
Prevalence[edit | edit source]
Although no numbers are given, the Interstitial Cystitis Association states on their website that a "small subset of interstitial cystitis (IC) patients" also have chronic fatigue syndrome (CFS).
Individuals with ME/CFS had a worse prognosis for their IC symptoms, according to a 2013 study of patients with IC.
The International Consensus Criteria for myalgic encephalomyelitis list interstitial cystitis as a comorbidity often found in people with ME, and list cystitis as a potential trigger of ME. The Canadian Consensus Criteria for ME/CFS also lists IC as a comorbidity.
Possible causes[edit | edit source]
No one knows the exact cause of IC. Bladder wall abnormalities exist in people with IC, but it's not clear whether these are the cause of the condition or the result of some other underlying process.
Notable studies[edit | edit source]
- 2013, Prognostic factors for recent-onset interstitial cystitis/painful bladder syndrome
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), pp. 8, 12, ISBN 978-0-9739335-3-6
- Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 13, doi:10.1300/J092v11n01_02
myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.