José Alegre

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José Alegre, also known as José Alegre-Martin, MD, PhD, works in the Internal Medicine Division, CFS/ME Clinical Unit, Vall d ́Hebron University Hospital, Research Institute Vall d’Hebron Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.[1]

Education[edit | edit source]

  • 1982 - B.S. in Medicine, School of Medicine, Autonoma University of Barcelona, Spain[1]
  • 1990 - PhD, in Medicine, School of Medicine, Autonoma University of Barcelona, Spain[1]

EUROMENE[edit | edit source]

Dr. Alegre is a Member of the Clinical Research Enablers And Diagnostic Criteria Working Group for EUROMENE, a European Union not-for-profit research organization committed to tackling the cause and treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[2]

Patents[edit | edit source]

  • June 2010, Patent No 10380071.0 – 2107: Use of alpha-1-antitrypsin for the preparation of medicaments for the treatment of chronic fatigue syndrome. Inventors: Dr. Ana Maria Garcia Quintana and Dr. José Alegre Martin, Propietor Grifols, SA.[1]
  • Dec 2010, Patent No US 2010/0331261: Use of alpha-1-antitrypsin for the preparation of drugs for the treatment of chronic fatigue syndrome. Inventors: Ana Garcia Quintana, José Alegre Martin.[1]

Notable studies[edit | edit source]


Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 1.2 1.3 1.4 "CURRICULUM VITAE - Jose Alegre, MD; PhD" (PDF). euromene.eu. Retrieved February 5, 2020.
  2. ↑ Euromene: Clinical Research Enablers and Diagnostic Criteria Working Group
  3. ↑ Suárez, Andrea; Guillamó, Elisabet; Roig, Teresa; Blázquez, Alicia; Alegre, José; Bermúdez, Jordi; Ventura, José Luis; García-Quintana, Ana María; Comella, Agustí (June 2010). "Nitric Oxide Metabolite Production During Exercise in Chronic Fatigue Syndrome: A Case-Control Study". Journal of Women's Health. 19 (6): 1073–1077. doi:10.1089/jwh.2008.1255. ISSN 1540-9996.
  4. ↑ Curriu, Marta; Carrillo, Jorge; Massanella, Marta; Rigau, Josepa; Alegre, José; Puig, Jordi; Garcia-Quintana, Ana M; Castro-Marrero, Jesús; Negredo, Eugènia; Clotet, Bonaventura; Cabrera, Cecilia; Blanco, Julià (2013), "Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome", Journal of Translational Medicine, 11 (68), doi:10.1186/1479-5876-11-68
  5. ↑ Castro-Marrero, J.; Cordero, M.D.; Sáez-Francas, N.; Jimenez-Gutierrez, C.; Aguilar-Montilla, F.J.; Aliste, L.; Alegre-Martin, J. (2013), "Could mitochondrial dysfunction be a differentiating marker between chronic fatigue syndrome and fibromyalgia?", Antioxidants & Redox Signaling, 19 (15): 1855-1860, doi:10.1089/ars.2013.5346, PMID 23600892
  6. ↑ Faro, M.; Sáez-Francàs, N.; Castro-Marrero, J.; Aliste, L.; Collado, A.; Alegre, J. (2014), "Impact of the fibromyalgia in the chronic fatigue syndrome", Medicina Clinica (Barc), 142 (12): 519-525, doi:10.1016/j.medcli.2013.06.030, PMID 24387955
  7. ↑ Santamarina-Perez, Pilar; Eiroa-Orosa, Francisco Jose; Rodriguez-Urrutia, Amanda; Qureshi, Adil; Alegre, Jose (August 13, 2013). "Neuropsychological Impairment in Female Patients with Chronic Fatigue Syndrome: A Preliminary Study". Applied Neuropsychology: Adult. 21 (2): 120–127. doi:10.1080/09084282.2013.771264. ISSN 2327-9095.
  8. ↑ Castro-Marrero, J.; Cordero, M.D.; Segundo, M.J.; Sáez-Francàs, N.; Calvo, N.; Román-Malo, L.; Aliste, L.; Fernández de Sevilla, T.; Alegre, J. (2015), "Does Oral Coenzyme Q10 Plus NADH Supplementation Improve Fatigue and Biochemical Parameters in Chronic Fatigue Syndrome?", Antioxidants & Redox Signaling, 22 (8): 679–685, doi:10.1089/ars.2014.6181, PMID 25386668
  9. ↑ Sáez-Francàs, Naia; Calvo, Natalia; Alegre, José; Castro-Marrero, Jesús; Casas, Miguel (2015), "Childhood trauma in Chronic Fatigue Syndrome: focus on personality disorders and psychopathology", Comprehensive Psychiatry, 62: 13-19, doi:10.1016/j.comppsych.2015.06.010
  10. ↑ Faro, Mónica; Sáez-Francàs, Naia; Castro-Marrero, Jesús; Aliste, Luisa; Fernández de Sevilla, Tomás; Alegre, Jose (2015), "Gender Differences in Chronic Fatigue Syndrome", Reumatologia clinica, 12 (2), doi:10.1016/j.reuma.2015.05.007
  11. ↑ Calvo, Natalia; Sáez-Francàs, Naia; Valero, Sergi; Castro-Marrero, Jesús; Alegre Martín, José; Casas, Miquel (July 2017). "Diagnostic Concordance Between Categorical and Dimensional Instruments to Assess Personality Disorder in Chronic Fatigue Syndrome: PDQ-4+ and TCI-R". European Journal of Psychological Assessment. 33 (3): 158–165. doi:10.1027/1015-5759/a000281. ISSN 1015-5759.
  12. ↑ Castro-Marrero, Jesus; Sáez-Francàs, Naia; Santillo, Dafna; Alegre, Jose (March 2017). "Treatment and management of chronic fatigue syndrome/myalgic encephalomyelitis: all roads lead to Rome: Therapy and management in CFS/ME". British Journal of Pharmacology. 174 (5): 345–369. doi:10.1111/bph.13702. PMC 5301046. PMID 28052319.
  13. ↑ Castro-Marrero, J.; Faro, M.; Aliste, L.; Sáez-Francàs, N.; Calvo, N.; Martínez-Martínez, A.; de Sevilla, T.F.; Alegre, J. (2017), "Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study", Psychosomatics, 58 (5): 533 - 543, doi:10.1016/j.psym.2017.04.010
  14. ↑ Cambras, T.; Castro-Marrero, J.; Zaragoza, MC.; Díez-Noguera, A.; Alegre, J. (2018), "Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis", PLoS ONE, 13 (6): e0198106, doi:10.1371/journal.pone.0198106
  15. ↑ Castro-Marrero, Jesús; Zaragozá, Maria Cleofé; González-Garcia, Sergio; Aliste, Luisa; Sáez-Francàs, Naia; Romero, Odile; Ferré, Alex; Fernández de Sevilla, Tomás; Alegre, José (2018), "Poor self-reported sleep quality and health-related quality of life in patients with chronic fatigue syndrome/myalgic encephalomyelitis", J Sleep Res: e12703, doi:10.1111/jsr.12703, PMID 29770505
  16. ↑ Castro-Marrero, Jesús; Serrano-Pertierra, Esther; Oliveira-Rodríguez, Myriam; Zaragozá, Maria Cleofé; Martínez-Martínez, Alba; Blanco-López, María del Carmen; Alegre, José (2018), "Circulating extracellular vesicles as potential biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis: an exploratory pilot study", Journal of Extracellular Vesicles, 7 (1), doi:10.1080/20013078.2018.1453730
  17. ↑ Calvo, Natalia; Pueyo, Natalia; Gutiérrez, Fernando; Ferrer, Marc; Castro-Marrero, Jesús; Alegre, José; Casas, Miquel; Ramos Quiroga, Josep-Antoni; Sáez-Francàs, Naia (July 2018). "Dimensional Personality Assessment among a Chronic Fatigue Syndrome (CFS) sample with Personality Inventory for DSM-5 (PID-5)". Actas Espanolas De Psiquiatria. 46 (4): 125–132. ISSN 1578-2735. PMID 30079926.
  18. ↑ Estévez-López, Fernando; Castro-Marrero, Jesus; Wang, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Nacul, Luis; Sepúlveda, Nuno; Strand, Elin B.; Pheby, Derek; Alegre, José; Scheibenbogen, Carmen; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Lacerda, Eliana; Murovska, Modra (September 1, 2018). "Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review". BMJ Open. 8 (9): e020817. doi:10.1136/bmjopen-2017-020817. ISSN 2044-6055. PMID 30181183.
  19. ↑ Castro-Marrero, Jesús; Zaragozá, Maria Cleofé; Domingo, Joan Carles; Martinez-Martinez, Alba; Alegre, José; von Schacky, Clemens (December 2018). "Low omega-3 index and polyunsaturated fatty acid status in patients with chronic fatigue syndrome/myalgic encephalomyelitis". Prostaglandins, Leukotrienes and Essential Fatty Acids. 139: 20–24. doi:10.1016/j.plefa.2018.11.006. ISSN 0952-3278.
  20. ↑ Castro-Marrero, Jesús; Faro, Mónica; Zaragozá, María Cleofé; Aliste, Luisa; de Sevilla, Tomás Fernández; Alegre, José (December 2019). "Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain". BMC Public Health. 19 (1). doi:10.1186/s12889-019-7225-z. ISSN 1471-2458. PMC 6599355. PMID 31253111.
  21. ↑ Escorihuela, Rosa María; Capdevila, Lluís; Castro, Juan Ramos; Zaragozà, María Cleofé; Maurel, Sara; Alegre, José; Castro-Marrero, Jesús (December 2020). "Reduced heart rate variability predicts fatigue severity in individuals with chronic fatigue syndrome/myalgic encephalomyelitis". Journal of Translational Medicine. 18 (1): 4. doi:10.1186/s12967-019-02184-z. ISSN 1479-5876. PMC 6943898. PMID 31906988.
  22. ↑ Cheema, Amanpreet K.; Sarria, Leonor; Bekheit, Mina; Collado, Fanny; Almenar‐Pérez, Eloy; Martín‐Martínez, Eva; Alegre, Jose; Castro‐Marrero, Jesus; Fletcher, Mary A.; Klimas, Nancy; Oltra, Elisa; Nathanson, Lubov (April 14, 2020). "Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender-specific changes in the microRNA expression profiling in ME/CFS". Journal of Cellular and Molecular Medicine. 00: 1–13. doi:10.1111/jcmm.15260. ISSN 1582-4934. PMID 32291908.
  23. ↑ Estévez-López, Fernando; Mudie, Kathleen; Wang-Steverding, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Castro-Marrero, Jesús; Nacul, Luis; Alegre, Jose; Zalewski, Paweł; Słomko, Joanna; Bolle Strand, Elin; Pheby, Derek; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Scheibenbogen, Carmen; Sepúlveda, Nuno; Murovska, Modra; Lacerda, Eliana (May 2020). "Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology". Journal of Clinical Medicine. 9 (5): 1557. doi:10.3390/jcm9051557.
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