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Allodynia refers to pain caused by what would normally be non-painful stimulation, for example brushing the skin.[1] Temperature change, light touching, and clothing can trigger the pain response resulting in a burning sensation often occurring after an injury to a site.[2]

Presentation[edit | edit source]

There are three types of allodynia. Tactile, where pain is caused by touches such as clothing touching the skin or someone lightly touching the arm; Mechanical, caused by movement across the skin when drying with a towel or sheets brushing against the skin; and Thermal, which is caused by heat or cold that is not extreme enough to cause damage to skin tissues.[3]

Allodynia in ME/CFS and Fibromyalgia[edit | edit source]

Allodynia is not a diagnostic symptom of ME or CFS, and is not even referred to in the International Consensus Criteria Primer for ME although over forms of pain are.[4]

Prevalence[edit | edit source]

A study of over 3,000 patients with fibromyalgia found that allodynia was "surprisingly common."[5]

Notable studies[edit | edit source]

  • 2009, Models and Mechanisms of Hyperalgesia and Allodynia[1](Full text)
  • 2010, A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles[5](Full text)

Possible causes[edit | edit source]

Central pain sensitization (increased response of neurons) has been proposed as a possible cause, but this term has conflicting definitions and scientific evidence is unclear.[1][2]

Potential treatments[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

International Consensus Criteria (ICC) - A set of diagnostic criteria, based on the Canadian Consensus Criteria, that argued for the abandonment of the term "chronic fatigue syndrome" and encouraged the sole use of the term "myalgic encephalomyelitis".

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.