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Serotonin norepinephrine reuptake inhibitor
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Serotonin Norepinephrine Reuptake Inhibitors or Selective Serotonin-Norepinephrine Reuptake Inhibitors or SNRIs are a class of antidepressant medication used for depression, anxiety and sometimes other uses. Some SNRIs also licensed for chronic pain including nerve pain, e.g. cymbalta (duloxetine), fibromyalgia, or used off-label for other non-psychiatric conditions.[1][2]
SNRIs include:
- Duloxetine (brand name Cymbalta)
- Milnacipran (Savella)
- Venlafaxine (Effexor)
ME/CFS[edit | edit source]
SNRIs are ineffective as a primary treatment for ME/CFS, but may be used to treat some symptoms such as pain, or for co-existing conditions like reactive depression.[3][4]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "List of SNRIs + Uses, Types & Side Effects". Drugs.com. Retrieved November 20, 2021.
- ↑ "List of 30 Fibromyalgia Medications Compared". Drugs.com. Retrieved November 20, 2021.
- ↑ Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
- ↑ Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02
