Pyridoxal-5'-phosphate

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Vitamin B6 (pyridoxal-5'-phosphate, P5P, PLP, pyridoxine, pyridoxamine) is a co-factor in amino acid metabolism, the folate cycle, and the biosynthesis of neurotransmitters, including dopamine, GABA, melatonin, norepinephrine, and serotonin.

Role in the body[edit | edit source]

Vitamin B6 is a cofactor for diamine oxidase, the enzyme that breaks down histamine. It is also a cofactor of histidine decarboxylase, the enzyme that catalyzes the decarboxylation of histidine to form histamine.

Chronic fatigue syndrome[edit | edit source]

One very small study found decreased functional status of several B vitamins including pyridoxine, riboflavin and thiamine.[1]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Heap, L. C.; Peters, T. J.; Wessely, S. (Apr 1, 1999), "Vitamin B Status in Patients with Chronic Fatigue Syndrome", Journal of the Royal Society of Medicine, 92 (4): 183–185, doi:10.1177/014107689909200405, ISSN 0141-0768, PMID 10450194, retrieved Nov 9, 2016 

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.