GABA
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Gamma aminobutyric acid (GABA), is a neurotransmitter made from the amino acid glutamate. GABA is the chief inhibiting, or calming neurotransmitter in the brain, functioning as a brake on the neural circuitry during stress. Low GABA levels are associated with restlessness, anxiety, insomnia and a low mood/depression. GABA works to balance glutamate (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.[citation needed]
Supplements to support GABA and glutamate are:
- amino acids GABA
- L-theanine
- N-acetyl-cysteine (NAC)
- vitamin B6
- vitamin D
- magnesium
- zinc
- Omega 3 fatty acid, and
- inositol[citation needed]
Notable studies[edit | edit source]
- 2005, GABA and glutamate systems as therapeutic targets in depression and mood disorders[1]
- 2005, Beyond monoamines: glutamatergic function in mood disorders[2]
- 2006, Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans[3]
- 2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3)
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ Kendell, Steven F.; Krystal, John H.; Sanacora, Gerrard (February 2005). "GABA and glutamate systems as therapeutic targets in depression and mood disorders". Expert Opinion on Therapeutic Targets. 9 (1): 153–168. doi:10.1517/14728222.9.1.153. ISSN 1744-7631. PMID 15757488.
- ↑ Kugaya, Akira; Sanacora, Gerard (October 2005). "Beyond monoamines: glutamatergic function in mood disorders". CNS spectrums. 10 (10): 808–819. doi:10.1017/s1092852900010403. ISSN 1092-8529. PMID 16400244.
- ↑ Abdou, Adham M.; Higashiguchi, S.; Horie, K.; Kim, Mujo; Hatta, H.; Yokogoshi, H. (2006). "Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans". BioFactors (Oxford, England). 26 (3): 201–208. doi:10.1002/biof.5520260305. ISSN 0951-6433. PMID 16971751.
