GABA

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Gamma aminobutyric acid (GABA), is a neurotransmitter made from the amino acid glutamate. GABA is the chief inhibiting, or calming neurotransmitter in the brain, functioning as a brake on the neural circuitry during stress. Low GABA levels are associated with restlessness, anxiety, insomnia and a poor mood. GABA works to balance glutamate (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.[citation needed]

Supplements to support GABA & glutamate are: amino acids GABA, L-theanine, N-acetyl-cysteine (NAC), vitamin B6, vitamin D, magnesium, zinc, omega 3, and inositol.

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glutamate - a salt or ester of glutamic acid which functions as the principal excitatory neurotransmitter in brain

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.