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Gamma aminobutyric acid (GABA), is a neurotransmitter made from the amino acid glutamate. GABA is the chief inhibiting, or calming neurotransmitter in the brain, functioning as a brake on the neural circuitry during stress. Low GABA levels are associated with restlessness, anxiety, insomnia and a poor mood. GABA works to balance glutamate (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.
Notable studies[edit | edit source]
- 2005, GABA and glutamate systems as therapeutic targets in depression and mood disorders
- 2005, Beyond monoamines: glutamatergic function in mood disorders
- 2006, Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans
- 2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3)
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
glutamate (Glu) - Glutamate is one of the amino acids used by the body to make proteins. It is a salt or ester of glutamic acid, and the terms glutamate and glutamic acid are often used interchangeably. It also functions as the principal excitatory neurotransmitter in the brain.