ME/CFS[edit | edit source]
The Open Medicine Foundation's ME/CFS Severely Ill Big Data Study found that patients in the study group with severe ME had one of several defects involving the IDO2 gene, which affected tryptophan - kynurenine metabolism. This lead to the Metabolic Trap theory.
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- "Medical Definition of KYNURENINE". www.merriam-webster.com. Retrieved Nov 30, 2019.
- National Center for Biotechnology Information. "Kynurenine". PubChem Database. Retrieved Jan 19, 2020.
- Phair, Robert D.; Davis, Ronald W.; Kashi, Alex A. (2019). "The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS". Diagnostics. 9 (3): 82. doi:10.3390/diagnostics9030082.