ME/CFS Severely Ill, Big Data Study

The ME/CFS Severely Ill, Big Data Study, led by Ronald Davis, will conduct a comprehensive, “Big Data” analysis on severely ill ME/CFS patients with the goal of finding sensitive and distinctive molecular biomarker(s).

Phase One - comprehensive testing

The first phase of the trial includes a very wide array of biological tests which have been defined and published.

...comprehensive/extensive testing of severely ill patients. By thoroughly checking blood, urine, and other body products, we expect to find biological abnormalities that could explain the debilitating symptoms. We don’t want to miss anything. So we’re doing it completely the first time.

In July 2016 it was announced that sample collection was complete.

Preliminary results

In March 2016, it was announced that the study had a significant result in the area of mitochondria. This resulted in the addition of Robert Naviaux (a mitochondrial expert) to the research team.

Results: Chemical signatures in blood

Metabolic features of chronic fatigue syndrome

Learn more

• Community Support Moves Severely Ill Chronic Fatigue Syndrome (ME/CFS) Study Forward Rapidly

See also

• Naviaux Lab
• Open Medicine Foundation
• End ME/CFS Project

See myalgic encephalomyelitis.

See chronic fatigue syndrome.

mitochondria Important parts of the biological cell, with each mitochondrion encased within a mitochondrial membrane. Mitochondria are best known for their role in energy production, earning them the nickname "the powerhouse of the cell". Mitochondria also participate in the detection of threats and the response to these threats. One of the responses to threats orchestrated by mitochondria is apoptosis, a cell suicide program used by cells when the threat can not be eliminated.