Theory[edit | edit source]
Evidence[edit | edit source]
No clinical trials have been conducted for hydrocodone in ME/CFS patients.
ME/CFS[edit | edit source]
The International Consensus Criteria Primer for physicians and Canadian Consensus Criteria both state that opioids like codeine should only be used for severe pain, and with a management plan in place. No particular opioids are suggested.
Clinicians[edit | edit source]
Risks and safety[edit | edit source]
The Royal College of Anaesthetists states that opioids, including codeine, rarely result in addiction when taken by people in pain, but they can become less effective over time (opioid tolerance), dependency may develop, and withdrawal effects can occur when opiods are stopped or doses are decreased.
Cost and availability[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- "Hydrocodone-Acetaminophen Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing". WebMD. Retrieved January 6, 2023.
- The Royal College of Anaesthetists (2016). "Taking Opioids for Pain | Information for Patients". rcoa.ac.uk. Retrieved October 3, 2018.
- Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
- Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02