Carl-Gerhard Gottfries
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Carl-Gerhard Gottfries, MD, PhD, is a Swedish professor, ME/CFS doctor, and founder of the Gottfries Clinic, Mölndal, Sweden. After developing chronic fatigue syndrome following a case of the flu, he discovered that monthly injections of a staphylococcus aureus vaccine boosted his immune system, successfully allowing him to return to work. He has continued using a staphylococcus vaccine injection every month for over fifty years.[1]
Clinic[edit | edit source]
Gottfries Clinic AB (Gottfriesmottagningen), was previously financed through the health-care system, but now is privately operated. It is a specialty clinic for the 1) evaluation, diagnosis and treatment of patients with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), chronic fatigue and widespread muscular pain, and 2) research for developing and treatment for such patients. Located at Krokslätts Torg 5, Mölndal, Sweden.[2]
2017 Ramsay Award[edit | edit source]
A team comprised of Dr. Jonas Bergquist and Dr. Jonas Blomberg of Uppsala University and Dr. Carl-Gerhard Gottfries and Dr. Olof Zachrisson of the Gottfries Clinic were awarded a 2017 Ramsay Award grant from the Solve ME/CFS Initiative for research into biomarkers for initiation (infection) and metabolic derangement in ME/CFS.[3]
Talks and interviews[edit | edit source]
- Sept 2014, Interview with Professor Carl-Gerhard Gottfries, Part 1: Background and Vaccine
- Sept 2014, Interview with Professor Carl-Gerhard Gottfries, Part 2: Experience and The Clinic
- Sept 2014, Interview with Professor Carl-Gerhard Gottfries, Part 3: The Clinic and Urgent Needs
- Sept 2014, Interview with Professor Carl-Gerhard Gottfries, Part 4: Continued Research
Notable studies[edit | edit source]
- 1997, Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome[4] (Abstract)
- 1998, Effects of staphylococcus toxoid vaccine on pain and fatigue in patients with fibromyalgia/chronic fatigue syndrome[5] (Abstract)
- 2000, Nickel Allergy is Found in a Majority of Women with Chronic Fatigue Syndrome and Muscle Pain - and may be Triggered by Cigarette Smoke and Dietary Nickel Intake [6](Abstract)
- 2002, A rating scale for fibromyalgia and chronic fatigue syndrome (the FibroFatigue scale)[7] (Abstract)
- 2004, Immune modulation with a staphylococcal preparation in fibromyalgia/chronic fatigue syndrome: relation between antibody levels and clinical improvement[8] (Abstract)
- 2006, Long-Term Treatment with a Staphylococcus Toxoid Vaccine in Patients with Fibromyalgia and Chronic Fatigue Syndrome[9] (Abstract)
- 2011, Murine gammaretrovirus group G3 was not found in Swedish patients with myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia[10] (Full Text)
- 2012, No evidence for xenotropic murine leukemia-related virus infection in Sweden using internally controlled multiepitope suspension array serology[11] (Full Text)
- 2013, Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis[12] (Full Text)
- 2015, Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia[13](Full Text)
- 2018, Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model[14] (Full Text)
- 2018, A randomised controlled trial of the monoaminergic stabiliser (-)-OSU6162 in treatment of myalgic encephalomyelitis/chronic fatigue syndrome[15] (Abstract)
- 2019, Antibodies to Human Herpesviruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients[16] - (Abstract)
- 2020, Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients – A validation study in plasma and cerebrospinal fluid from two Swedish cohorts[17] - (Full text)
See also[edit | edit source]
- Staphylococcus aureus
- Staphylococcus vaccine
- Sweden
- Dr Markov's chronic bacterial intoxication syndrome (CBIS) theory of ME/CFS (Dr Markov has evidence that ME/CFS is caused by a dysbiosis in the kidneys)
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "Carl-Gerhard Gottfries: A Swedish Chronic Fatigue Syndrome Story".
- ↑ http://www.gottfriesclinic.se/in-english/gottfries-clinic/
- ↑ http://solvecfs.org/2017-ramsay-award-program-results/
- ↑ Regland, B; Andersson, M; Abrahamsson, L; Bagby, J; Dyrehag, LE; Gottfries, CG (1997). "Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome". Scandinavian Journal of Rheumatology. 26 (4): 301–7. PMID 9310111.
- ↑ Andersson, M; Bagby, JR; Dyrehag, L; Gottfries, C (1998). "Effects of staphylococcus toxoid vaccine on pain and fatigue in patients with fibromyalgia/chronic fatigue syndrome". European Journal of Pain. 2 (2): 133–142. PMID 10700309.
- ↑ Regland, Bjorn; Zachrisson, Olof; Stejskal, Vera; Gottfries, Carl Gerhard (2000). "Immunotherapy of Chronic Fatigue Syndrome: Therapeutic Interventions Aimed at Modulating the Th1/Th2 Cytokine Expression Balance". Journal of Chronic Fatigue Syndrome. 8 (1): 57–65. doi:10.1300/J092v08n01_04.
- ↑ Zachrisson, O; Regland, B; Jahreskog, M; Kron, M; Gottfries, CG (June 2002). "A rating scale for fibromyalgia and chronic fatigue syndrome (the FibroFatigue scale)". J Psychosomatic Research. 52 (6): 501–9. PMID 12069875.
- ↑ Zachrisson, O; Colque-Navarro, P; Gottfries, CG; Regland, B; Möllby, R (February 2004). "Immune modulation with a staphylococcal preparation in fibromyalgia/chronic fatigue syndrome: relation between antibody levels and clinical improvement". European Journal of Clinical Microbiology & Infectious Disease. 23 (2): 98–105. doi:10.1007/s10096-003-1062-8.
- ↑ Carl-Gerhard Gottfries, Ove Häger, Björn Regland & Olof Zachrisson. (2006). Long-Term Treatment with a Staphylococcus Toxoid Vaccine in Patients with Fibromyalgia and Chronic Fatigue Syndrome. Journal of Chronic Fatigue Syndrome, Vol. 13, Iss. 4, pp. 29-40. DOI:10.1300/J092v13n04_04
- ↑ Elfaitouri, A; Shao, X; Mattsson Ulfstedt, J; Muradrasoli, S; Bölin Wiener, A; Golbob, S; Ohrmalm, C; Matousek, M; Zachrisson, O; Gottfries, C-G; Blomberg, J (2011), "Murine gammaretrovirus group G3 was not found in Swedish patients with myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia.", PLoS One, 6 (10), doi:10.1371/journal.pone.0024602
- ↑ Blomberg, Jonas; Blomberg, Fredrik; Sjösten, Anna; Sheikholvaezin, Ali; Bölin-Wiener, Agnes; Elfaitouri, Amal; Hessel, Sanna; Gottfries, Carl-Gerhard; Zachrisson, Olof; Öhrmalma, Christina; Jobs, Magnus; Pipkorn, Rüdiger (2012), "No Evidence for Xenotropic Murine Leukemia-Related Virus Infection in Sweden Using Internally Controlled Multiepitope Suspension Array Serology", Clinical and Vaccine Immunology, 19 (9): 1399-1410, doi:10.1128/CVI.00391-12
- ↑ Elfaitouri, A; Herrmann, B; Bölin-Wiener, A; Wang, Y; Gottfries, C-G; Zachrisson, O; Pipkorn, R; Rönnblom, L; Blomberg, J (2013), "Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis", PLoS One, 8 (11), doi:10.1371/journal.pone.0081155
- ↑ Regland, Björn; Forsmark, Sara; Halaouate, Lena; Matousek, Michael; Peilot, Birgitta; Zachrisson, Olof; Gottfries, Carl-Gerhard (2015), "Response to Vitamin B12 and Folic Acid in Myalgic Encephalomyelitis and Fibromyalgia.", PLoS ONE, 10 (4), doi:10.1371/journal.pone.0124648
- ↑ Blomberg, Jonas; Gottfries, Carl-Gerhard; Elfaitouri, Amal; Rizwan, Muhammad; Rosén, Anders (2018), "Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model", Frontiers in Immunology, 2018 (9): 229, doi:10.3389/fimmu.2018.00229
- ↑ Nilsson, MKL; Zachrisson, O; Gottfries, C; Matousek, M; Peilot, B; Forsmark, S; Schuit, RC; Carlsson, ML; Kloberg, A; Carlsson, A (June 2018). "A randomised controlled trial of the monoaminergic stabiliser (-)-OSU6162 in treatment of myalgic encephalomyelitis/chronic fatigue syndrome". Acta Neuropsychiatrica. 30 (3): 148–157. doi:10.1017/neu.2017.35. PMID 29212562.
- ↑ Blomberg, Jonas; Rizwan, Muhammad; Böhlin-Wiener, Agnes; Elfaitouri, Amal; Julin, Per; Zachrisson, Olof; Rosén, Anders; Gottfries, Carl-Gerhard. "Antibodies to Human Herpesviruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients". Frontiers in Immunology. doi:10.3389/fimmu.2019.01946.
- ↑ Bynke, Annie; Julin, Per; Gottfries, Carl-Gerhard; Heidecke, Harald; Scheibenbogen, Carmen; Bergquist, Jonas (August 1, 2020). "Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients – A validation study in plasma and cerebrospinal fluid from two Swedish cohorts". Brain, Behavior, & Immunity - Health. 7: 100107. doi:10.1016/j.bbih.2020.100107. ISSN 2666-3546.
