Nitrogen hypothesis
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The nitrogen hypothesis or nitrogen metabolism hypothesis of ME/CFS was first proposed by Christopher Armstrong in 2018.[1]
Theory[edit | edit source]
According to the Open Medicine Foundation, the nitrogen hypothesis states that: "nitrogen-containing by-products of energy production accumulate more readily in the cells of people with ME / CFS, these nitrogen-containing by-products can be damaging to the cells and their process of producing energy".[1]
Evidence[edit | edit source]
In 2020, the Open Medicine Foundation announced that Christopher Armstrong had been awarded a grant to investigate the nitrogen hypothesis at the Open Medicine Foundation's ME/CFS Collaborative Research Center at Stanford University, run by the Dr. Ron Davis.[1]
In Aug 2020, the Open Medicine Foundation stated "Armstrong first noted increased usage of amino acids, which contains nitrogen, in the metabolism of people with ME/CFS while working at the University of Melbourne. He was the first to apply metabolomics to the field of ME/CFS, publishing his results in 2015. Metabolomics is the study of small molecules (metabolites) using common standards of detection that enable different studies to be comparative and additive."[1]
Treatment[edit | edit source]
None has been proposed yet.
Articles and blogs[edit | edit source]
- Aug 29, 2020, Grant Awarded to Nitrogen Hypothesis Study: OMF Scientist Receives Grant Funding for ME/CFS Study
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ 1.0 1.1 1.2 1.3 "Grant Awarded to Nitrogen Hypothesis Study". Open Medicine Foundation. August 29, 2020. Retrieved August 29, 2020.
