Lysozyme
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Lysozyme or muramidase is a protein and enzyme present in tears, saliva and other bodily fluids.[1]
Lysozyme is found in certain types of white blood cells (neutrophils and macrophages.[2]
Function
Lysozyme helps block or restrict the growth of bacteria by damaging their cell walls.[2]
ME/CFS
Maes et al. (2012) found that levels of lysozyme and neopterin were significantly higher in patients with ME/CFS compared to patients with chronic fatigue and healthy controls.[3]
Notable studies
- 2012, Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin.[3] - (Abstract)
- 2021, The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups[4] - (Full text)
See also
Learn more
References
- ↑ "Definition of LYSOZYME". Merriam-Webster Medical Dictionary. Retrieved February 12, 2021.
- ↑ 2.0 2.1 "lysozyme". Taber's Medical Dictionary. Retrieved February 12, 2021.
- ↑ 3.0 3.1 Maes, Michael; Twisk, Frank N.M.; Kubera, Marta; Ringel, Karl (February 2012). "Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin". Journal of Affective Disorders. 136 (3): 933–939. doi:10.1016/j.jad.2011.09.004. ISSN 0165-0327.
- ↑ Maes, Michael; Kubera, Marta; Stoyanova, Kristina; Leunis, Jean-Claude (January 29, 2021). "The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups". Preprints. doi:10.20944/preprints202101.0623.v1. Retrieved February 12, 2021.
