Lysozyme
Lysozyme or muramidase is a protein and enzyme present in tears, saliva and other bodily fluids.[1]
Lysozyme is found in certain types of white blood cells (neutrophils and macrophages.[2]
Function[edit | edit source]
Lysozyme helps block or restrict the growth of bacteria by damaging their cell walls.[2]
ME/CFS[edit | edit source]
Maes et al. (2012) found that levels of lysozyme and neopterin were significantly higher in patients with ME/CFS compared to patients with chronic fatigue and healthy controls.[3]
Notable studies[edit | edit source]
- 2012, Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin.[3] - (Abstract)
- 2021, The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups[4] - (Full text)
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "Definition of LYSOZYME". Merriam-Webster Medical Dictionary. Retrieved February 12, 2021.
- ↑ 2.02.1 "lysozyme". Taber's Medical Dictionary. Retrieved February 12, 2021.
- ↑ 3.03.1 Maes, Michael; Twisk, Frank N.M.; Kubera, Marta; Ringel, Karl (February 2012). "Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin". Journal of Affective Disorders. 136 (3): 933–939. doi:10.1016/j.jad.2011.09.004. ISSN 0165-0327.
- ↑ Maes, Michael; Kubera, Marta; Stoyanova, Kristina; Leunis, Jean-Claude (January 29, 2021). "The Reification of the Clinical Diagnosis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups". Preprints. doi:10.20944/preprints202101.0623.v1. Retrieved February 12, 2021.
enzyme a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.
myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.
The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.
