Antiviral: Difference between revisions

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==Studies==
==Studies==
*2006, Use of [[valganciclovir]] in patients with elevated antibody titers against [[Human herpesvirus 6|Human Herpesvirus-6]] (HHV-6) and [[Epstein-Barr virus|Epstein-Barr Virus]] (EBV) who were experiencing [[central nervous system]] dysfunction including long-standing [[fatigue]].<ref>{{Cite journal | last = Kogelnik | first = AM |  authorlink = Andreas Kogelnik | last2 = Loomis | first2 = K | last3 = Hoegh-Petersen | first3 = M | last4 = Rosso | first4 = F | last5 = Hischier | first5 = C | last6 = Montoya | first6 = JG |  authorlink6 = Jose Montoya | date = | title = Use of valganciclovir in patients with elevated antibody titers against Human Herpesvirus-6 (HHV-6) and Epstein-Barr Virus (EBV) who were experiencing central nervous system dysfunction including long-standing fatigue | url =https://www.ncbi.nlm.nih.gov/pubmed/17276366|journal=Journal of Clinical Virology|volume=37| pages=Suppl 1:S33-8|doi=10.1016/S1386-6532(06)70009-9|pmid=17276366|via=}}</ref> [https://www.ncbi.nlm.nih.gov/pubmed/17276366 (Abstract)]
*2006, Use of [[valganciclovir]] in patients with elevated antibody titers against [[Human herpesvirus 6|Human Herpesvirus-6]] (HHV-6) and [[Epstein-Barr virus|Epstein-Barr Virus]] (EBV) who were experiencing [[central nervous system]] dysfunction including long-standing [[fatigue]].<ref>{{Cite journal | last = Kogelnik | first = AM |  authorlink = Andreas Kogelnik | last2 = Loomis | first2 = K | last3 = Hoegh-Petersen | first3 = M | last4 = Rosso | first4 = F | last5 = Hischier | first5 = C | last6 = Montoya | first6 = JG |  authorlink6 = Jose Montoya | date = | title = Use of valganciclovir in patients with elevated antibody titers against Human Herpesvirus-6 (HHV-6) and Epstein-Barr Virus (EBV) who were experiencing central nervous system dysfunction including long-standing fatigue | url =https://www.ncbi.nlm.nih.gov/pubmed/17276366|journal=Journal of Clinical Virology|volume=37| pages=Suppl 1:S33-8|doi=10.1016/S1386-6532(06)70009-9|pmid=17276366|via=}}</ref> [https://www.ncbi.nlm.nih.gov/pubmed/17276366 (Abstract)]
* 2012, Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers<ref name="Watt, 2012">{{Cite journal | last1 = Watt | first1 = T | authorlink1 = | last2 = Oberfoell | first2 = S| authorlink2 = | last3 = Balise | first3 = R | authorlink3 = | last4 = Lunn | first4 = MR | authorlink4 = | last5 = Kar | first5 = AK | authorlink5 = | last6 = Merrihew| first6 = LE | authorlink6 = | last7 = Bhangoo | first7 = MS | authorlink7 = | last8 =Montoya | first8 = JG | authorlink8 = Jose Montoya | title = Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers | journal = Journal of Medical Virology | volume = 84 |  issue = 12 | page = 1967-1974 | date = 2012 | pmid = 23080504 | doi = 10.1002/jmv.23411 | url = https://doi.org/10.1002%2Fjmv.23411 }}</ref> ([https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.23411 Abstract])
* 2012, Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers<ref name="Watt, 2012">{{Cite journal | last1 = Watt | first1 = T | authorlink1 = | last2 = Oberfoell | first2 = S | authorlink2 = | last3 = Balise | first3 = R | authorlink3 = | last4 = Lunn | first4 = MR | authorlink4 = | last5 = Kar | first5 = AK | authorlink5 = | last6 = Merrihew| first6 = LE | authorlink6 = | last7 = Bhangoo | first7 = MS | authorlink7 = | last8 =Montoya | first8 = JG | authorlink8 = Jose Montoya | title = Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers | journal = Journal of Medical Virology | volume = 84 |  issue = 12 | page = 1967-1974 | date = 2012 | pmid = 23080504 | doi = 10.1002/jmv.23411 | url = https://doi.org/10.1002%2Fjmv.23411 }}</ref> ([https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.23411 Abstract])
* 2017, A [[famciclovir]] + [[celecoxib]] combination treatment is safe and efficacious in the treatment of fibromyalgia.<ref>{{Cite journal | last = Pridgen | first = William L | authorlink = William Pridgen | last2 = Duffy | first2 = Carol | authorlink2 = Carol Duffy | last3 = Gendreau| first3 = Judy F | authorlink3 = Judy Gendreau | last4 = Gendreau| first4 = R Michael | authorlink4 = Michael Gendreau | authorlink5 = | date = 2017-02-22 | title = A famciclovir + celecoxib combination treatment is safe and efficacious in the treatment of fibromyalgia | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328426/|journal=Journal of Pain Research|volume=10|issue= | pages = 451–460|doi=10.2147/JPR.S127288|issn=1178-7090|pmc=5328426|pmid=28260944|quote=|via=}}</ref> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328426/ Full text])
* 2017, A [[famciclovir]] + [[celecoxib]] combination treatment is safe and efficacious in the treatment of fibromyalgia.<ref>{{Cite journal | last = Pridgen | first = William L | authorlink = William Pridgen | last2 = Duffy | first2 = Carol | authorlink2 = Carol Duffy | last3 = Gendreau| first3 = Judy F | authorlink3 = Judy Gendreau | last4 = Gendreau| first4 = R Michael | authorlink4 = Michael Gendreau | authorlink5 = | date = 2017-02-22 | title = A famciclovir + celecoxib combination treatment is safe and efficacious in the treatment of fibromyalgia | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328426/|journal=Journal of Pain Research|volume=10|issue= | pages = 451–460|doi=10.2147/JPR.S127288|issn=1178-7090|pmc=5328426|pmid=28260944|quote=|via=}}</ref> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328426/ Full text])
* 2018, [[Migraine]] Headache Treated with [[Famciclovir]] and [[Celecoxib]]: A Case Report.<ref>{{Cite journal | last = NaPier | first = Bradford Lee | authorlink = | last2 = Morimoto | first2 = Maki | authorlink2 = | last3 = NaPier | first3 = Erin | date = 2017-11-29 | title = Migraine Headache Treated with Famciclovir and Celecoxib: A Case Report | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737915/|journal=The Permanente Journal|volume=22|issue=| pages=|doi=10.7812/TPP/17-020|issn=1552-5767|pmc=5737915|pmid=29236660|quote=|via=}}</ref> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737915/ Full text])
* 2018, [[Migraine]] Headache Treated with [[Famciclovir]] and [[Celecoxib]]: A Case Report.<ref>{{Cite journal | last = NaPier | first = Bradford Lee | authorlink = | last2 = Morimoto | first2 = Maki | authorlink2 = | last3 = NaPier | first3 = Erin | date = 2017-11-29 | title = Migraine Headache Treated with Famciclovir and Celecoxib: A Case Report | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737915/|journal=The Permanente Journal|volume=22|issue=| pages=|doi=10.7812/TPP/17-020|issn=1552-5767|pmc=5737915|pmid=29236660|quote=|via=}}</ref> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737915/ Full text])

Revision as of 15:37, March 30, 2023

Antiviral drugs are a class of medication used specifically for treating viral infections, rather than bacterial, fungal or other infections. Most antivirals are used for a specific type of virus, while a broad-spectrum antiviral is effective against a wider range of viruses. Although there are a number of broad-spectrum antibiotics, there are very few broad-spectrum antiviral drugs, and the few in existence are generally only effective against a specific family of viruses.[citation needed]

Tenofovir and lamivudine are antiviral drugs which are designed for HIV, but may be effective against other retroviruses. Valacyclovir is often used for Herpes Simplex Virus (HSV) I and II, as well as for Varicella Zoster Virus (VZV), another herpesviruses. Valganciclovir is used for a broader spectrum of herpesviruses, including HSV I and II, VZV, cytomegalovirus (CMV), Epstein-Barr virus (EBV), and is somewhat effective against Human Herpesvirus 6 (HHV6). Ribavirin is the only antiviral drug effective against RNA viruses, although it is rarely used due to its toxic side-effects.

Evidence[edit | edit source]

Importance to ME/CFS[edit | edit source]

Studies[edit | edit source]

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Learn more[edit | edit source]

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