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Vascular endothelial growth factor
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
 | This article is a stub. |
Vascular Endothelial Growth Factor (VEGF) or Vascular Endothelial Growth Factor A (VEGF-A) is a signal protein produced by cells that stimulates blood vessel formation (vasculogenesis and angiogenesis).[1] Vascular Endothelial Growth Factor was originally known as vascular permeability factor (VPF).
The VEGF family help maintain blood vessel and lymphatic systems.[1]
ME/CFS[edit | edit source]
Landi et al. (2016) found lower levels of VEGF, IL-7 and IL-16 in 100 long-term ME/CFS patients compared to controls but studies by Horning et al. (2015) and Montoya et al. (2017) did not find this statistically significant.[2][3]
Notable studies[edit | edit source]
- 2016, Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ Jump up to: 1.0 1.1 Maniscalco, W. M.; D’Angio, C.T. (January 1, 2006). Laurent, Geoffrey J.; Shapiro, Steven D. (eds.). VASCULAR ENDOTHELIAL GROWTH FACTOR. Oxford: Academic Press. pp. 413–418. ISBN 978-0-12-370879-3.
- ↑ Landi, Abdolamir; Broadhurst, David; Vernon, Suzanne D.; Tyrrell, D. Lorne J.; Houghton, Michael (February 2016). "Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome". Cytokine. 78: 27–36. doi:10.1016/j.cyto.2015.11.018. ISSN 1096-0023. PMID 26615570.
- ↑ Giloteaux, Ludovic; O'Neal, Adam; Castro-Marrero, Jesús; Levine, Susan M.; Hanson, Maureen R. (October 12, 2020). "Cytokine profiling of extracellular vesicles isolated from plasma in myalgic encephalomyelitis/chronic fatigue syndrome: a pilot study". Journal of Translational Medicine. 18 (1): 387. doi:10.1186/s12967-020-02560-0. ISSN 1479-5876.
