Small heart syndrome

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Small heart syndrome is associated with a small heart shadow on a chest X-ray or magnetic resonance imaging. It was first proposed in 1944 as "neurocirculatory asthenia." Current studies show that small heart syndrome is associated with a smaller left ventricular chamber size and diminished cardiac stroke volume.[1]

Small heart syndrome is characterized with weakness or fatigue even after ordinary exertion, heart palpitation, dyspnea, and fainting. Miwa and Fujita have shown that it is significantly more prevalent in ME/CFS patient (61%) compared to a control group (24%).[2]

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  1. 1.01.1 Miwa, Kunihisa; Fujita, Masatoshi (2011), "Small Heart With Low Cardiac Output for Orthostatic Intolerance in Patients With Chronic Fatigue Syndrome", Clinical Cardiology, 34 (12): 782–786, doi:10.1002/clc.20962 
  2. 2.02.1 Miwa, Kunihisa; Fujita, Masatoshi (2008), "Small Heart Syndrome in Patients with Chronic Fatigue Syndrome", Clinical Cardiology, 31 (7): 328–333, doi:10.1002/clc.20227, PMID 18636530 

orthostatic intolerance (OI) - The development of symptoms when standing upright, where symptoms are relieved upon reclining. Patients with orthostatic intolerance have trouble remaining upright for more than a few seconds or a few minutes, depending upon severity. In severe orthostatic intolerance, patients may not be able to sit upright in bed. Orthostatic intolerance is often a sign of dysautonomia. There are different types of orthostatic intolerance, including postural orthostatic tachycardia syndrome (POTS).

chronic fatigue syndrome (CFS) - A controversial term, invented by the U.S. Centers for Disease Control, that generally refers to a collection of symptoms as “fatigue”. There have been multiple attempts to come up with a set of diagnostic criteria to define this term, but few of those diagnostic criteria are currently in use. Previous attempts to define this term include the Fukuda criteria and the Oxford criteria. Some view the term as a useful diagnostic category for people with long-term fatigue of unexplained origin. Others view the term as a derogatory term borne out of animus towards patients. Some view the term as a synonym of myalgic encephalomyelitis, while others view myalgic encephalomyelitis as a distinct disease.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.