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Small heart syndrome

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Small heart syndrome is associated with a small heart shadow on a chest X-ray or magnetic resonance imaging. It was first proposed in 1944 as "neurocirculatory asthenia." Current studies show that small heart syndrome is associated with a smaller left ventricular chamber size and diminished cardiac stroke volume.[1]

Small heart syndrome is characterized with weakness or fatigue even after ordinary exertion, heart palpitation, dyspnea, and fainting. Miwa and Fujita have shown that it is significantly more prevalent in ME/CFS patient (61%) compared to a control group (24%).[2]

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