SEPTAD
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The SEPTAD is a name given by some clinicians treating Myalgic encephalomyelitis and Mast cell activation syndrome to a constellation of comorbidities and pathophysiological or pathogenic processes that tend to make up these patients’ clinical presentations.
The SEPTAD include:
- Ehlers-Danlos Syndrome / Hypermobility
- Dysautonomia and Postural orthostatic tachycardia syndrome
- Mast cell activation syndrome
- Chronic infections (for example, COVID-19, Lyme, Coxsackie B4, Epstein-Barr Virus)
- Gastroparesis and Small intestine bacterial overgrowth
- Autommunity
- Neurosurgical conditions (e.g., craniocervical instability, atlantoaxial instability, tethered cord syndrome, Eagle’s syndrome)
The name was originally coined by clinicians who are members of the MASTerminds listserv.[citation needed]