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Paroxetine
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Paroxetine is an antidepressant sold under the brand names Brisdelle, Paxil and Seroxat. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) and is used for depression, anxiety, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder.[1]
Theory[edit | edit source]
Evidence[edit | edit source]
The Canadian Consensus criteria for ME/CFS states that paroxetine may be useful for depression in people with ME/CFS.[2]
Risks and safety[edit | edit source]
Side effects include:
- Sweating
- Dizziness
- Nausea
- Asthenia
- Drowsiness
- Dry mouth
- Constipation
- Diarrhea
- anorexia
- Insomnia
- male sexual dysfunction
- Tremors[1][2]
Paroxetine has more anticholinergic side effects than fluoxetine (Prozac) or sertraline (Zoloft).
Costs and availability[edit | edit source]
Perscription only. Widely available.[1]
See also[edit | edit source]
Learn more[edit | edit source]
- Paroxetine - drugs.com
References[edit | edit source]
- ↑ Jump up to: 1.0 1.1 1.2 "Paroxetine". drugs.com. Retrieved February 20, 2021.
- ↑ Jump up to: 2.0 2.1 Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02
