Matthew Sorenson

Source: DePaul University

Matthew Sorenson, PhD, APN, ANP-C​​​, Director at School of Nursing, Associate Professor in Nursing, and a Consultant for the Myalgic Encephalomyelitis & Chronic Fatigue Syndrome Research Team at the Center for Community Research, College of Science and Health, DePaul University, Chicago, Illinois, US. His research interests include immunological changes in individuals with multiple sclerosis and chronic fatigue illnesses.

Book chapter

• 2013, The implications of sensitization and kindling for chronic fatigue syndrome

Notable studies

• 2007, Baseline Cortisol Levels Predict Treatment Outcomes in Chronic Fatigue Syndrome Nonpharmacologic Clinical Trial (Abstract)
• 2008, Evidence for T-helper 2 shift and association with illness parameters in chronic fatigue syndrome (CFS) (Full Text)
• 2009, Kindling and oxidative stress as contributors to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Full Text)
• 2010, Possible Genetic Dysregulation in Pediatric CFS (Full Text)
• 2010, A Comparison of Immune Functionality in Viral versus Non-Viral CFS Subtypes (Full Text)
• 2011, An Etiological Model for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Full Text)
• 2012, The Production of Interleukin-8 Is Increased in Plasma and Peripheral Blood Mononuclear Cells of Patients with Fatigue (Full Text)
• 2013, The implications of sensitization and kindling for chronic fatigue syndrome (Abstract with full text available upon request)
• 2014, Brain Derived Neurotrophic Factor is Decreased in Chronic Fatigue Syndrome and Multiple Sclerosis (Full Text)
• 2015, Novel Associations of F2-Isoprostanes, F3- Isoprostanes and Isofurans in Older Adults with Chronic Fatigue Syndrome: An Exploratory Study (Full Text)
• 2017, Differentiating Multiple Sclerosis from Myalgic Encephalomyelitis and Chronic Fatigue Syndrome (Full Text)
• 2017, Dysregulation of cytokine pathways in chronic fatigue syndrome and multiple sclerosis (Abstract) (Corrigendum)

Online presence

• PubMed
• ResearchGate

Learn more

• The Myalgic Encephalomyelitis & Chronic Fatigue Syndrome Research Team, DePaul University

etiology The cause of origin, especially of a disease.

plasma The liquid part of blood, lymph, or milk after removing any suspended material. Most of the time, "plasma" simply refers to blood, after all the blood cells have been removed. If you also remove the clotting factors, then the plasma is referred to as "serum".

See myalgic encephalomyelitis.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

See chronic fatigue syndrome.

cytokine any class of immunoregulatory proteins secreted by cells, especially immune cells. Cytokines are small proteins important in cell signaling that modulate the immune system. (Learn more: me-pedia.org)