Malcolm Hooper is Professor Emeritus of Medicine Chemistry at the University of Sunderland in the UK and an advocate for people living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). He chaired the Invest in ME International ME Conference in London in 2008, 2010 and 2011.
His numerous articles on ME, many of which were in collaboration with Margaret Williams, were mostly published on MEActionUK but can now be found on Margaret William's website.. A passionate critic of psychological theories and treatments for ME, his articles illustrate how the Wessely school have ignored the biomedical science on ME/CFS for almost 30 years.
Professor Hooper is also the President and Chief Scientific Adviser to the UK National Gulf Veterans and Families Association.
PACE trial criticism[edit | edit source]
Professor Hooper was the principal author of the 442 page report Magical Medicine: How to Make a Disease Disappear, a scathing criticism of the PACE trial released a year before the first results of the trial were published in the Lancet in 2011. This was followed up by numerous other articles listed below, including a formal Complaint to The Lancet, letters to the Medical Research Council, politicians, and others.
Prof. Hooper wrote an open letter to Dr. Richard Horton, editor of The Lancet on April 15, 2016, regarding the PACE trial and stating "Although not within your personal remit, subsequent papers flowing from it and purporting to validate the initial findings of the PACE study also need to be retracted...".
NICE guidelines criticism[edit | edit source]
Professor Hooper has written a number of articles critical of the NICE guidelines review process which resulted in the controversial 2007 NICE guidelines used by the UK's NHS. Hooper and Reid (2006) documented the issues with the expert evidence used in the NICE guidelines, which was produced by the University of York Centre for Reviews and Dissemination (CRD).
Major articles[edit | edit source]
- 2001, What is ME? What is CFS? Information for Clinicians and Lawyers
- 2001, Composite Response on the Final Version of the CMO’s Report of 31st August 2001 on CFS/ME
- 2001, Concepts of Accountability?
- 2001, Submission to Chief Medical Officer’s Working Group on CFS/ME
- 2003, The Mental Health Movement: Persecution of Patients?
- 2003, Ignoring the Evidence? A response to the final version of the MRCCFS/ME Research Advisory Group Strategy of 1st May 2003
- 2005, Gibson Inquiry: Illustrations of Clinical Observations and International Research Findings from 1955 to 2005 that demonstrate the organic aetiology of ME/CFS
- 2005, Gibson Inquiry: Concerns about Conflict of Interest
- 2005, ME - Why no Accountability? A synopsis for the Gibson Inquiry
- 2006, Inadequacy of the 2005 York Evidence Review for NICE - with Horace Reid
- 2006, A Response and Appreciation of the Gibson Inquiry Report
- 2007, Failure of Nice to Address its Remit
- 2007, Corporate Collusion? An overview of the misinformation about ME/CFS arising from vested interests that pervades some UK Departments of State and other Agencies
- 2007, Defiance of Science
- 2007, Memorandum to Health Select Committee re NICE
- 2010, Submission re: DSM-V and ME/CFS
- 2010, Magical Medicine: How to Make a Disease DisappearPress release
- 2011, Statistics and ME
- 2011, Further Concerns about the PACE Trial
- 2011, Detailed Response to Prof Peter White’s letter to The Lancet
- 2011, Complaint to The Lancet re PACE Trial
- 2012, Prof Wessely's Award of the Inaugural John Maddox Prize for his Courage in the Field of ME and Gulf War Syndrome
- 2013, Key concerns about the PACE Trial - for Lawyers
- 2013, The Role of the Science Media Centre and the Insurance Industry in ME/CFS
Journal articles[edit | edit source]
- 2007, Myalgic encephalomyelitis: a review with emphasis on key findings in biomedical research
Talks and interviews[edit | edit source]
- 2006, Speaker at the 1st Invest in ME International ME Conference - Summary of “Key Findings” of past bio‑medical research - (Video)
- 01May 2007, Day 1, Speaker at the 2nd Invest in ME International ME Conference - Summary of “Key Findings” of past bio‑medical research - (Video)
- 02 May 2007, Day 2, Speaker at the 2nd Invest in ME International ME Conference - Summary - Future Strategy for ME Research, Diagnosis and Treatment - (Video)
- 2008, Speaker at the 3rd Invest in ME International ME Conference - Opening Remarks as the Chair - DVD available
- 2010, Speaker at the 5th Invest in ME International ME Conference - Opening Remarks as the Chair - DVD available
- 2011, Speaker at the 6th Invest in ME International ME Conference - Opening Remarks as the Chair- DVD available
Online presence[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- "Invest in ME Research - UK Charity for Myalgic Encephalomyelitis Homepage". Invest in ME Research. Retrieved February 12, 2019.
- "Margaret Williams' website", margaretwilliams.me
- Hooper, Malcolm; Williams, Margaret (2003), Magical Medicine: How to Make a Disease Disappear
- "PACE Trial Key Dates and Chronology of Complaint" (PDF).
- "Open Letter to Richard Horton, Lancet, 4/15/16" (PDF). April 15, 2016.
- Hooper, Malcolm (November 19, 2017). "OFF THE PACE CMIs, BPS, PACE, GUIDELINES and CONSEQUENCES (PowerPoint)" (PDF). aonm.org.
- Hooper, Malcolm (November 2017). "OFF THE PACE: CMIs, BPS, PACE, GUIDELINES and CONSEQUENCES (Notes)" (PDF). aonm.org.
- Hooper, Malcolm; Reid, Horace (January 2006). "Inadequacy of the York (2005) Systematic Review of the CFS/ME Medical Evidence Base" (PDF). Retrieved February 14, 2019.
- Hooper, Malcolm (February 12, 2020). "Magical Medicine: How to Make a Disease Disappear" (PDF). Contributions from members of the ME community. Researched by Margaret Williams.
- Hooper, Malcolm (May 2007), "Myalgic encephalomyelitis: a review with emphasis on key findings in biomedical research", Journal of Clinical Pathology, 60 (5): 466–471, doi:10.1136/jcp.2006.042408
- "Invest in ME Research - IIMEC1". Invest in ME Research. Retrieved February 17, 2020.
- "Invest in ME Research - IIMEC3". Invest in ME Research. Retrieved February 17, 2020.
- "Invest in ME Research - IIMEC5 International ME Conference 2010". Invest in ME Research. Retrieved February 17, 2020.
- "Invest in ME Research - IIMEC6 International ME Conference 2011". Invest in ME Research. Retrieved February 17, 2020.
myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.