From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Leukotrienes are a family of eicosanoids produced by the oxidation of arachidonic acid by the enzyme arachidonate 5-lipoxygenase (ALOX5).

Leukotriene production is usually accompanied by the production of histamine and prostaglandins. Leukotrienes are important in asthma.

Leukotriene inhibitors[edit | edit source]

Leukotriene inhibitors are a potential treatment for mast cell diseases including mast cell activation syndrome.

Leukotriene inhibitors include Montelukast (Singulair), Zafirlukast (Accolate) and Zileuton (Zyflo/Zyflo CR).[1]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "Medications to Treat Mast Cell Diseases". The Mast Cell Disease Society. Retrieved February 16, 2021.