Kindling hypothesis

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

The Kindling hypothesis attempts to explain the hypersensitivities to pain, sensory input, and the immune system responses found in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[1] Kindling "occurs when an organism is exposed repeatedly to an initially sub-threshold stimulus resulting in hypersensitivity and spontaneous seizure-like activity."

Theory

Evidence

Treatment

See also

Learn more

  • An Etiological Model for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[1] (Full text)

References

  1. ↑ 1.0 1.1 Jason, Leonard A.; Sorenson, Matthew; Porter, Nicole; Belkairous, Natalie (March 1, 2011). "An Etiological Model for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Neuroscience and medicine. 2 (1): 14–27. doi:10.4236/nm.2011.21003. ISSN 2158-2912. PMC 3166239. PMID 21892413.
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