Indoleamine-2,3-dioxygenase 1 or IDO or IDO-1 is more commonly known as IDO1 is an enzyme in the kynurenine pathway involved in the metabolism of the essential amino acid tryptophan to N-formyl kynurenine. The gene encoding IDO1 is also sometimes referred to as IDO1.
Function[edit | edit source]
ME/CFS[edit | edit source]
Notable studies and publications[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
- IDO1 - National Center for Biotechnology Information
References[edit | edit source]
- National Center for Biotechnology Information (Mar 22, 2020). "IDO1 indoleamine 2,3-dioxygenase 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved May 1, 2020.
- Ball, Helen J.; Yuasa, Hajime J.; Austin, Christopher J. D.; Weiser, Silvia; Hunt, Nicholas H. (Mar 1, 2009). "Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway". The International Journal of Biochemistry & Cell Biology. 41 (3): 467–471. doi:10.1016/j.biocel.2008.01.005. ISSN 1357-2725.
- Phair, Robert D.; Davis, Ronald W.; Kashi, Alex A. (2019). "The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS". Diagnostics. 9 (3): 82. doi:10.3390/diagnostics9030082.
metabolic trap hypothesis - An hypothesis which proposes that the normal metabolic functioning of the cell has become "trapped" in an abnormal state, which may lead to body-wide symptoms.