Migraine
Migraine headaches commonly occur in people with ME/CFS. In a 2011 study by Ravindran, et al, migraine headaches were found in 84%, and tension-type headaches in 81% of a cohort of CFS patients.[1] This compared to 5% and 45%, respectively, in a cohort of healthy controls.[1]
Symptoms[edit | edit source]
Migraine without aura is defined by the following diagnostic criteria outlined inThe International Classification Of Headache Disorders, 3rd edition:
at least 5 episodes lasting 4 to 72 hr (untreated or unsuccessfully treated) with at least 2 of the following criteria:
(i) unilateral location;
(ii) pulsating quality;
(iii) moderate to severe pain intensity; and
(iv) aggravation by or causing avoidance of routine physical activity.
During the headache either nausea with or without vomiting, or photophobia and phonophobia must occur.[2][3]
Migraines in ME/CFS[edit | edit source]
Migraines is one of several illnesses or conditions experienced alongside of ME/CFS.[4]
The Canadian Consensus Criteria recognizes migraines in the possible neurological symptoms of ME/CFS.
Possible causes[edit | edit source]
Potential treatments[edit | edit source]
- Triptans, e.g. Sumatriptan, brand name Imitrex (13 out of 14 newly diagnosed migraine subjects responded to sumatriptan in one CFS patient cohort)[1] or Zomitriptan, brand name Zomig[5]
- Avoiding consumption of nitrates and tyramine
- Daith piercing[6]
- CGRP antagonists including gepants and CGRP monoclonal antibodies[7]
Notable studies[edit | edit source]
- 2011, Migraine headaches in chronic fatigue syndrome (CFS): comparison of two prospective cross-sectional studies.[1]
- 2013, Migraine in gulf war illness and chronic fatigue syndrome: Prevalence, potential mechanisms, and evaluation.[8] (Full Text)
- 2016, Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort (Full Text)[9]
See also[edit | edit source]
Learn more[edit | edit source]
- Oct 18, 2016, Migraines could be caused by gut bacteria, study suggests[10]
- May 19, 2018, The Migraine Drug Explosion Begins: Could Fibromyalgia and ME/CFS Benefit?[11]
References[edit | edit source]
- ↑ 1.0 1.1 1.2 1.3 Ravindran, Murugan K; Zheng, Yin; Timbol, Christian; Merck, Samantha J; Baraniuk, James N (March 5, 2011). "Migraine headaches in Chronic Fatigue Syndrome (CFS): Comparison of two prospective cross-sectional studies". BMC Neurology. 11 (1). doi:10.1186/1471-2377-11-30. ISSN 1471-2377. PMID 21375763.
- ↑ Headache Classification Subcommittee of the International Headache Society (2004). "The International Classification of Headache Disorders: 2nd edition". Cephalalgia: An International Journal of Headache. 24 (Suppl 1): 9–160. ISSN 0333-1024. PMID 14979299.
- ↑ "Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition". Cephalalgia. 38 (1): 1–211. January 1, 2018. doi:10.1177/0333102417738202. ISSN 0333-1024.
- ↑ "Overlapping Conditions – American ME and CFS Society". ammes.org. Retrieved August 12, 2018.
- ↑ "Migraine Guide: Causes, Symptoms and Treatment Options". Drugs.com. Retrieved October 12, 2021.
- ↑ Cascio Rizzo, Angelo; Paolucci, Matteo; Altavilla, Riccardo; Brunelli, Nicoletta; Assenza, Federica; Altamura, Claudia; Vernieri, Fabrizio (2017). "Daith Piercing in a Case of Chronic Migraine: A Possible Vagal Modulation". Frontiers in Neurology. 8. doi:10.3389/fneur.2017.00624. ISSN 1664-2295. PMC 5711775. PMID 29230190.
- ↑ Negro, Andrea; Martelletti, Paolo (June 2019). "Gepants for the treatment of migraine". Expert Opinion on Investigational Drugs. 28 (6): 555–567. doi:10.1080/13543784.2019.1618830. ISSN 1744-7658. PMID 31081399.
- ↑ Rayhan, Rakib U.; Ravindran, Murugan K.; Baraniuk, James N. (2013). "Migraine in gulf war illness and chronic fatigue syndrome: prevalence, potential mechanisms, and evaluation". Frontiers in Physiology. 4: 181. doi:10.3389/fphys.2013.00181. ISSN 1664-042X. PMID 23898301.
- ↑ Gonzalez, Antonio; Hyde, Embriette; Sangwan, Naseer; Gilbert, Jack A.; Virre, Erik; Knight, Rob (October 18, 2016). "Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort" (PDF). American Society for Microbiology. 1 (5).
- ↑ Devlin, Hannah (October 18, 2016). "Migraines could be caused by gut bacteria, study suggests". the Guardian. Retrieved August 11, 2018.
- ↑ Johnson, Cort (May 19, 2018). "The Migraine Drug Explosion Begins: Could Fibromyalgia and ME/CFS Benefit? - Health Rising". Health Rising. Retrieved August 11, 2018.
