Zofran

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Zofran or ondansetron (generic name, oral) is drug used to treat nausea and vomiting.[1] It is a 5-HT3 receptor antagonist.[2] Zofran is also sold under the brand names Zofran ODT and Zuplenz.[1]

Theory[edit | edit source]

Evidence[edit | edit source]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Serious side effects may occur with zofran including:

  • blurred vision or vision loss (lasting from a few minutes to several hours)
  • Slowed heart rate
  • Difficultty breathing
  • Anxiety
  • Agitation
  • Shivering
  • feeling like you might pass out
  • Urinating less than usual or not urinating at all

Zofran may impair your thinking or reactions, which may make driving unsafe.[1]

Costs and availability[edit | edit source]

Notable studies[edit | edit source]

  • 2009, Treatment of chronic fatigue syndrome with 5-HT3 receptor antagonists - preliminary results[2] (Abstract)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 "Zofran Uses, Dosage & Side Effects". Drugs.com. Retrieved November 29, 2020.
  2. 2.0 2.1 Späth, M.; Färber, D., L.; Welzel, D. (January 1, 2000). "Treatment of chronic fatigue syndrome with 5-HT3 receptor antagonists - preliminary results". Scandinavian Journal of Rheumatology. 29 (113): 72–77. doi:10.1080/030097400750001851-1. ISSN 0300-9742.