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Prostaglandin
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
 | This article is a stub. |
 | This article needs cleanup to meet MEpedia's guidelines. The reason given is: This page needs additional references or sources for verification - multiple references need to be added. (Oct 10, 2019) |
Prostaglandins are a subclass of eicosanoids derived from long chain fatty acids.
Prostaglandins are involved in a diverse range of functions including vasodilation, uterus contraction, pain, gastric acid secretion, and autonomic neurotransmitters.
Prostaglandins can also by pyrogenic.
Synthesis[edit | edit source]
They are found in almost all cells with a nucleus. They are produced by the oxidation of arachidonic acid, DGLA or EPA from the cell membrane by phospholipase A2.
Exercise[edit | edit source]
In healthy people, Prostaglandin E2 levels are raised significantly for days after exercise.[1]
References[edit | edit source]
- ↑ Gray, J. B; Martinovic, A. M (July 1, 1994). "Eicosanoids and essential fatty acid modulation in chronic disease and the chronic fatigue syndrome". Medical Hypotheses. 43 (1): 31–42. doi:10.1016/0306-9877(94)90046-9. ISSN 0306-9877.
