Outcome switching

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Outcome switching is when authors of a clinical trial "move the goal posts" during a trial to achieve the desired results.

The PACE trial authors, in a clinical trial of ME/CFS patients undergoing GET/CBT, employed this tactic.

Articles on Outcome switching in clinical trials[edit | edit source]

Tracking outcome switching

PACE trial[edit | edit source]

  • David Tuller spoke about and answered questions on the PACE trial and its flaws.
  • Feb 28, 2016, David Tuller gave a speech with Q&As. That speech can be viewed here.[7]

Learn more[edit | edit source]

See also[edit | edit source]

  • Alem Matthees won the Freedom of Information Act request for PACE trial data.

References[edit | edit source]

  1. Lane, Christopher (Apr 30, 2016). "How Outcome Switching is Corrupting Medical Research". Psychology Today. Retrieved 2018-08-11. 
  2. "For my next trick..." The Economist. Mar 26, 2016. Retrieved 2018-08-11. 
  3. Miseta, Ed (Mar 7, 2016). "Is Outcome Switching Still A Problem In Clinical Trials". www.clinicalleader.com. Retrieved 2018-08-11. 
  4. Belluz, Julia (Dec 29, 2015). "How researchers dupe the public with a sneaky practice called "outcome switching"". Vox. Retrieved 2018-08-11. 
  5. "Tracking switched outcomes in clinical trials". COMPare. Retrieved 2018-08-11. 
  6. Rehmeyer, Julie (Aug 1, 2016). "Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of t…". www.slideshare.net. Retrieved 2018-08-11 – via SlideShare. 
  7. Tuller, David (Mar 28, 2016). "Lezing dr David Tuller met Nederlandse ondertiteling". YouTube. ME/cvs Vereniging. 
  8. Tuller, David (Mar 4, 2016). "Interview with David Tuller (Amsterdam, 27th February 2016)". YouTube. Frank Twisk. 
  9. "PACE trial - MEpedia". me-pedia.org. Retrieved 2018-08-11. 


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history