Outcome switching
Outcome switching is when authors of a clinical trial "move the goal posts" during a trial to achieve the desired results.
The PACE trial authors, in a clinical trial of ME/CFS patients undergoing GET/CBT, employed this tactic.
Contents
Articles on Outcome switching in clinical trials[edit | edit source]
- How Outcome Switching is Corrupting Medical Research[1]
- For my next trick... [2]
- Is Outcome Switching Still A Problem In Clinical Trials?[3]
- How researchers dupe the public with a sneaky practice called "outcome switching"[4]
Tracking outcome switching
PACE trial[edit | edit source]
- In 2016, Julie Rehmeyer gave the talk Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of the PACE Trial Slideshow given at the 2016 Joint Statistics Meetings[6] (Notes may be be viewed by clicking the “Notes” icon just above the comments section in the slideshow link.)
- David Tuller spoke about and answered questions on the PACE trial and its flaws.
- Feb 27, 2016, While in Amsterdam at The Forgotten Plague Conference, David Tuller gave an interview with Frank Twisk discussing the flaws of the Pace trial. That interview can be viewed here.[8]
Learn more[edit | edit source]
See also[edit | edit source]
- Alem Matthees won the Freedom of Information Act request for PACE trial data.
References[edit | edit source]
- ↑ Lane, Christopher (Apr 30, 2016). "How Outcome Switching is Corrupting Medical Research". Psychology Today. Retrieved 2018-08-11.
- ↑ "For my next trick..." The Economist. Mar 26, 2016. Retrieved 2018-08-11.
- ↑ Miseta, Ed (Mar 7, 2016). "Is Outcome Switching Still A Problem In Clinical Trials". www.clinicalleader.com. Retrieved 2018-08-11.
- ↑ Belluz, Julia (Dec 29, 2015). "How researchers dupe the public with a sneaky practice called "outcome switching"". Vox. Retrieved 2018-08-11.
- ↑ "Tracking switched outcomes in clinical trials". COMPare. Retrieved 2018-08-11.
- ↑ Rehmeyer, Julie (Aug 1, 2016). "Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of t…". www.slideshare.net. Retrieved 2018-08-11 – via SlideShare.
- ↑ Tuller, David (Mar 28, 2016). "Lezing dr David Tuller met Nederlandse ondertiteling". YouTube. ME/cvs Vereniging.
- ↑ Tuller, David (Mar 4, 2016). "Interview with David Tuller (Amsterdam, 27th February 2016)". YouTube. Frank Twisk.
- ↑ "PACE trial - MEpedia". me-pedia.org. Retrieved 2018-08-11.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history