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Opioid-induced hyperalgesia

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Opioid-Induced Hyperalgesia or OIH is defined as "is a state of enhanced pain sensitization in patients who are on chronic opioid therapy".[1]

Opioid-induced hyperalgesia causes a much lower pain threshold, which means that pain is greater when opiods are taken compared to when they are not used - which is the opposite of a normal response.

Signs and symptoms[edit | edit source]

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ME/CFS[edit | edit source]

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References[edit | edit source]

  1. Yi, Peter; Pryzbylkowski, Peter (October 2015). "Opioid Induced Hyperalgesia". Pain Medicine. 16 (suppl 1): S32–S36. doi:10.1111/pme.12914. ISSN 1526-2375.