From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Glucocorticoid is a corticosteroid, often simply referred to as a steroid.

ME/CFS[edit | edit source]

Studies published in 2017 and 2018 by de Vega et al. found dysregulated glucocorticoid receptor function in people with ME/CFS. While glucocorticoids are anti-inflammatory in the periphery, they can be inflammatory to the central nervous system; these findings suggest this effect may be amplified in people with ME/CFS due to increased sensitivity to glucocorticoids.[1]

Studies[edit | edit source]

  • 2000, Decreased bone mineral density during low dose glucocorticoid administration in a randomized, placebo controlled trial.[2] (Abstract)
  • 2017, Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[3] (Full text)

References[edit | edit source]